Tissue Engineering News and Research

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Dramatic advances in the fields of biochemistry, cell and molecular biology, genetics, biomedical engineering and materials science have given rise to the remarkable new cross-disciplinary field of tissue engineering. Tissue engineering uses synthetic or naturally derived, engineered biomaterials to replace damaged or defective tissues, such as bone, skin, and even organs.

Biologically engineered blood vessels now an option in cardiac bypass

The first-ever human use of completely biologically engineered blood vessels grown from a person's own cells could be an option for people who have vessels too damaged for heart bypass, researchers reported at the American Heart Association's Scientific Sessions 2005.

16 Nov 2005

Scientists use stem cells to grow cartilage

Scientists from Imperial College London have successfully converted human embryonic stem cells into cartilage cells, offering encouragement that replacement cartilage could one day be grown for transplantation.

16 Nov 2005

World first trial grows blood vessels from patient's own skin

A team of American scientists have successfully implanted blood vessels grown entirely from a patient's own cells.

16 Nov 2005

How cells use very slow biological flows to signal and organize

An EPFL (Ecole Polytechnique Federale de Lausanne) team led by professor Melody Swartz has demonstrated for the first time that the presence of very slow biological flows affects the extracellular environment in ways that are critical for tissue formation and cell migration.

25 Oct 2005

Tissue engineering used to reconstruct defective tracheas (windpipes) in fetal lambs

Researchers at Children's Hospital Boston report using tissue engineering to reconstruct defective tracheas (windpipes) in fetal lambs, first using cells from the amniotic fluid to grow sections of cartilage tube, and then implanting these living grafts into the lambs while still in the womb.

9 Oct 2005

Stem cells help regenerate cartilage and bone

UK scientists are working on new methods to regenerate cartilage and bone by delivering genes to stem cells within the body to instruct them to turn into bone cells.

28 Sep 2005

Delicate balance of induction and inhibition in determining tooth cusps

One of the remaining challenges for evolutionary developmental studies of mammals, whose evolution is best known from their teeth, is how their tooth shape is altered during development.

26 Sep 2005

Human tissue grown from stem cells, available for transplant in the next four years

A team of researchers from the University of Liverpool in the UK have embarked on an ambitious project which could see human tissue grown from stem cells, available for transplant in the next four years.

5 Sep 2005

Scientists convert human embryonic stem cells into lung cells

According to research to be published in the journal Tissue Engineering, the team from Imperial College London, took human embryonic stem cells and 'directed' them to convert into the type of cells needed for gas exchange in the lung, known as mature small airway epithelium.

24 Aug 2005

New skin from fetal cells great success in children with burns

Swiss researchers have used skin constructed from fetal skin cells to treat eight children with burns.

21 Aug 2005

Immune system more concerned with damage detected than foreign invaders, such as viruses

A well-respected researcher who is now a chief of an immunology laboratory of the National Institutes of Health (NIH) has rocked the boat in the past few years for the experts in the understanding of the autoimmune system.

15 Aug 2005

Even vegetarians can eat this meat!

New techniques proposed by an international research team, could mean the mass production of meat reared was not on the farm, but in the laboratory.

15 Aug 2005

In vivo engineering of organs: The bone bioreactor

An international team of biomedical engineers has demonstrated for the first time that it is possible to grow healthy new bone reliably in one part of the body and use it to repair damaged bone at a different location.

25 Jul 2005

Engineered tissue is more viable with blood of its own

By adding small blood vessels to artificially grown muscle tissue, the chances of succesful tissue 'repair' rise. Without nourishing blood, thicker tissue has limited viability.

21 Jul 2005

Scientists successfully isolate stem cells from human skin

Scientists at Wake Forest University School of Medicine have successfully isolated stem cells from human skin, expanded them in the laboratory and coaxed them into becoming fat, muscle and bone cells.

27 Jun 2005

Researchers use novel cocktail of cells to coax muscle tissue to develop its own vascular network

For years, a major obstacle has dashed the hopes of creating "replacement parts" for the human body: the lack of an internal, nourishing blood system in engineered tissues. Without it, thicker tissues can't thrive, which has confined tissue engineering's practical application to thin skin, which can recruit blood vessels from underlying tissue.

20 Jun 2005

New complete muscle grown in the lab

A multinational team of researchers has grown new muscle complete with its own network of blood vessels in the laboratory, and implanted the new muscle in a living mouse. The accomplishment is a first for tissue engineering, according to a report in the June 19 issue of Nature Biotechnology.

19 Jun 2005

U.S. scientists have successfully engineered blood vessels from human vascular cells in the lab

Tissue engineering has made considerable progress in the past decade, but advances have stopped short of clinical application for most tissues. For elderly patients tissue-engineered arteries could provide grafts for bypass surgery.

16 Jun 2005

Engineers have found a way to modify a plastic to anchor molecules that promote nerve regeneration, blood vessel growth or other biological processes

In the study led by Dr. Christine Schmidt, the researchers identified a piece of protein from among a billion candidates that could perform the unusual feat of attaching to polypyrrole, a synthetic polymer (plastic) that conducts electricity and has shown promise in biomedical applications.

17 May 2005

Tissue engineering to grow bone, ligaments and cartilage

A future in which laboratory-grown organs and stimulated growth of muscle, bones and nerves could play a major role in treating medical conditions was revealed at a recent Tissue Engineering Symposium at Wake Forest University Baptist Medical Center.

11 Apr 2005