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HU3DINKS project to develop human tissue-based bioinks for 3D bioprinting

Biofabrication or 3D bioprinting aims to create tissue constructs for numerous applications including animal free testing, drug screening and regenerative medicine.

28 Jul 2023

New gene editing approach could revolutionize the treatment of blood disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

27 Jul 2023

Two infusions of IL-15-expressing CAR NK Cells boost survival in lymphoma mouse models

A new study led by researchers at The University of Texas MD Anderson Cancer Center discovered loss of metabolic fitness in chimeric antigen receptor (CAR) natural killer (NK) cells is a critical mechanism of resistance, with infused cells gradually losing the ability to compete with tumor cells for nutrients, leading to tumor relapse.

26 Jul 2023

MD Anderson and Nexo Therapeutics partner to advance new cancer therapies against previously undruggable targets

The University of Texas MD Anderson Cancer Center and Nexo Therapeutics today announced a multi-year strategic collaboration that aligns the innovative technology and capabilities of each organization at the earliest stages of drug discovery and development to rapidly advance impactful new cancer therapies against previously undruggable targets.

26 Jul 2023

Can epigenetic changes explain the strong link between age and cancer?

Researchers reported the link between aging, cancer, and epigenomic changes.

26 Jul 2023

Tumor-derived GDF-15 suppresses immunotherapy response

Researchers evaluate the impact of tumor-derived GDF-15 on responses to anti-PD-1 immunotherapy.

26 Jul 2023

Biomimetic materials pulsed with low-energy blue light can reshape damaged corneas

An injectable biomaterial activated by pulses of low-energy blue light has tremendous potential for on-the-spot repair to the domed outer layer of the eye, a team of University of Ottawa researchers and their collaborators have revealed.

26 Jul 2023

New technique could improve early detection of cancer metastasis

Metastasis occurs when cancer cells acquire the ability to spread and form new tumors in different places in the body, usually by traveling within blood or lymph vessels.

24 Jul 2023

Discovery redefines current understanding of immune cell landscape in the human cornea

University of Melbourne researchers have discovered that the sentinels guarding the healthy human cornea from pathogens and inflammation are T cells, and not another type of immune cells called dendritic cells, as previously thought.

24 Jul 2023

Generating functional parathyroid glands from mouse embryonic stem cells

Regenerative medicine has opened up exciting possibilities in the world of medicine. Now, researchers in Japan are searching for ways to recreate and rebuild body tissues and organs, which may be an alternative cure for diseases.

24 Jul 2023

Improving gut health may be key to slowing HIV progression to AIDS

Restoring and improving gut health may be key to slowing HIV progression to AIDS, according to a new study by University of Pittsburgh infectious diseases scientists published today in the journal JCI Insight.

24 Jul 2023

Research reveals therapeutic potential of novel compound in inhibiting oncogene translation

Cutting-edge research at the Luxembourg Institute of Health reveals the ground-breaking therapeutic potential of the compound FL3 in inhibiting oncogene translation and rewiring cancer cell metabolism, opening up new therapeutic opportunities for leukemia patients.

24 Jul 2023

Fly-to-bedside resource offers new hope for COVID-19 treatments

Millions of deaths and ongoing illnesses caused by the COVID-19 pandemic have prompted scientists to seek new ways of understanding how viruses so skillfully enter and reprogram human cells.

21 Jul 2023

New ultra-flexible neural implant records single-neuron activity in deep-brain regions

A new ultra-small and ultra-flexible electronic neural implant, delivered via blood vessels, can record single-neuron activity deep within the brains of rats, according to new study.

20 Jul 2023

Study examines the antibacterial properties of cinnamon and eucalyptus essential oils compared with their isolated major compounds

A comparison of the antibacterial properties of Cinnamonum cassia and Eucalyptus globulus to their most abundant bioactives metabolites.

20 Jul 2023

New brain-penetrant agonist shows promise in protecting dopamine neurons for Parkinson's disease treatment

Researchers reported on Nurr1 as a promising therapeutic target for managing Parkinson's disease (PD).

20 Jul 2023

Advanced scans can detect hypertrophic cardiomyopathy before symptoms appear

The research, funded by the British Heart Foundation and published in the journal Circulation, opens the prospect of treating the condition at the earliest stages.

19 Jul 2023

SARS-CoV-2 spike protein's role in lung injury unraveled: promising new approach uncovered

Researchers investigated the effect of SARS-CoV-2 spike (S) protein subunit 1 (S1) on the pulmonary endothelium.

19 Jul 2023

Fentanyl overdose reversal: New hope on the horizon

According to the Centers for Disease Control, 100,000 Americans die each year from an overdose, most due to the use of synthetic opiates like fentanyl. While naloxone, currently the only an antidote for opiate overdose, has become more common, it is less effective against fentanyl-class synthetic opioids.

18 Jul 2023

An evaluation of the main nanotechnology approaches to improve the therapeutic potential of polyphenols against cancer

Researchers comprehensively evaluated all nanotechnology-based approaches.

18 Jul 2023

in vivo News and Research

HU3DINKS project to develop human tissue-based bioinks for 3D bioprinting

New gene editing approach could revolutionize the treatment of blood disorders

Two infusions of IL-15-expressing CAR NK Cells boost survival in lymphoma mouse models

MD Anderson and Nexo Therapeutics partner to advance new cancer therapies against previously undruggable targets

Can epigenetic changes explain the strong link between age and cancer?

Tumor-derived GDF-15 suppresses immunotherapy response

Biomimetic materials pulsed with low-energy blue light can reshape damaged corneas

New technique could improve early detection of cancer metastasis

Discovery redefines current understanding of immune cell landscape in the human cornea

Generating functional parathyroid glands from mouse embryonic stem cells

Improving gut health may be key to slowing HIV progression to AIDS

Research reveals therapeutic potential of novel compound in inhibiting oncogene translation

Fly-to-bedside resource offers new hope for COVID-19 treatments

New ultra-flexible neural implant records single-neuron activity in deep-brain regions

Study examines the antibacterial properties of cinnamon and eucalyptus essential oils compared with their isolated major compounds

New brain-penetrant agonist shows promise in protecting dopamine neurons for Parkinson's disease treatment

Advanced scans can detect hypertrophic cardiomyopathy before symptoms appear

SARS-CoV-2 spike protein's role in lung injury unraveled: promising new approach uncovered

Fentanyl overdose reversal: New hope on the horizon

An evaluation of the main nanotechnology approaches to improve the therapeutic potential of polyphenols against cancer

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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