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Study: ANGEL2 enzyme performs unique chemical reaction at the end of RNA molecules

Scientists led by Javier Martinez from the Max Perutz Labs, a joint venture of the Medical University of Vienna and the University of Vienna, have identified a unique chemical reaction at the end of RNA molecules for the first time in human cells.

31 Jul 2020

Researchers report a liquid biopsy for COVID-19

A new study published on the preprint server medRxiv in July 2020 reports the potential of cell-free DNA as a marker of the severity of disease in COVID-19. This could help triage patients as well as provide a prognostic marker.

30 Jul 2020

UOttawa's Faculty of Medicine awards 58 clinical research chairs to top clinician-scientists

The Faculty of Medicine has awarded 58 clinical research chairs to top clinician-scientists in a five-year, $40 million investment to drive clinical research excellence and enhance health and patient care.

30 Jul 2020

From swab to sequencing - scalable method for identifying SARS-CoV-2

A research group headed by Stanford University scientists has developed a scalable, high throughput method to generate high fidelity whole genome and HLA sequencing, viral genomes, and representation of human transcriptome from single nasopharyngeal swabs of coronavirus disease (COVID19) patients. Their results are published on the medRxiv preprint server.

30 Jul 2020

Study suggests new approach to make radiation therapy more effective for glioblastoma patients

Many modern cancer drugs target a specific genetic mutation that is driving a particular cancer's runaway growth and division -- such as the HER-2 protein in some breast cancers or EGFR in certain lung cancers.

30 Jul 2020

Mice born with Fragile X syndrome have fewer cell antennas

Structures called primary cilia - which act like TV antennas for cells to detect signals - are present in fewer numbers in mice born with Fragile X syndrome, according to researchers from The University of Texas Health Science Center at San Antonio.

30 Jul 2020

Researchers to investigate real-world effects of new cystic fibrosis medications

Researchers at RCSI University of Medicine and Health Sciences are leading a new €3m study to investigate the real-world effects of the newest cystic fibrosis medications as they become available for people with CF.

30 Jul 2020

Researchers identify targeted treatment strategy for malignant pleural mesothelioma

The reactivation of telomerase is a key mechanism in the unrestricted growth of cancer cells. Malignant pleural mesothelioma (MPM) is a form of cancer originating from the mesothelium, a cell layer covering the lungs and the inside of the chest wall.

30 Jul 2020

Researchers are developing comprehensive catalog of functional elements of human and mouse genomes

Scientists around the world have access to a rich trove of information through the Encyclopedia of DNA Elements (ENCODE)--annotated versions of the human and mouse genomes that are vital for interpreting their genetic codes.

30 Jul 2020

Partial loss of MYLPF gene can cause distal arthrogryposis, shows study

Jared Talbot is part of a 32-member international research team that identified a gene that, when altered, can cause bent fingers and toes, clubfoot, scoliosis, and short stature.

30 Jul 2020

Relatives of SARS-CoV-2 may pose a health threat for years to come

Coronaviruses are zoonotic viruses that jump from animals to humans and cause infection. There are many types of common human coronaviruses, which usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. Most people get infected with one or more of coronavirus types 229E, NL63, OC43, and HKU1 at some point in their lives.

29 Jul 2020

Antioxidant-rich foods may increase risk for bowel cancers, study finds

It is a fact that has long baffled doctors: Cancer in the small intestine is quite rare, whereas colorectal cancer, a neighboring though much smaller organ, is one of the leading causes of cancer death for men and women. What is it about the colon that seems to "attract" cancer?

29 Jul 2020

UC San Diego researchers part of special package of human genome studies

Researchers at University of California San Diego School of Medicine are among the contributors to a package of 10 studies, published July 29, 2020 in the journal Nature, describing the latest results from the ongoing Encyclopedia of DNA Elements (ENCODE) project, a worldwide effort led by the National Institutes of Health to understand how the human genome functions.

29 Jul 2020

Experts caution against routine use of current GEP tests for melanoma patients

A consensus statement published today in JAMA Dermatology by an international group of melanoma researchers evaluates the use of prognostic genetic expression profile (GEP) testing to guide clinical management of patients with melanoma.

29 Jul 2020

Study finds fungal isolates with high levels of virulence in different hospitals

A group of researchers from Brazil, Denmark, Italy and Spain analyzed 884 samples of fungi of the genus Candida collected from 16 hospitals and found a significant number of clusters in more than one hospital.

29 Jul 2020

New maps of chemical marks on DNA could help illuminate the causes of developmental disorders

In research that aims to illuminate the causes of human developmental disorders, Salk scientists have generated 168 new maps of chemical marks on strands of DNA--called methylation--in developing mice.

29 Jul 2020

Study reveals mechanisms of mechanical stretch induced skin expansion

The capacity of the skin to expand by mechanical stretching has been used for decades in plastic and reconstructive surgery to generate an excess of skin that can be used to repair birth defects, damaged tissues, and breast reconstruction after mastectomy.

29 Jul 2020

Study identifies novel function of SMS enzyme to facilitate colorectal cancer growth

A new study by researchers at the University of Kentucky identifies a novel function of the enzyme spermine synthase (SMS) to facilitate colorectal cancer growth.

29 Jul 2020

Deep learning algorithm can identify genetic alterations from routine histological images of tumors

Researchers at the University of Chicago Medicine Comprehensive Cancer Center, working with colleagues in Europe, created a deep learning algorithm that can infer molecular alterations directly from routine histology images across multiple common tumor types.

28 Jul 2020

'Synthetic lethality' could be exploited for cancer therapy

A Ludwig Cancer Research study has identified a new instance in which the simultaneous mutation of two nonessential genes--neither of which is on its own vital to cell survival--can cause cancer cell death.

28 Jul 2020

Genetic News and Research

Study: ANGEL2 enzyme performs unique chemical reaction at the end of RNA molecules

Researchers report a liquid biopsy for COVID-19

UOttawa's Faculty of Medicine awards 58 clinical research chairs to top clinician-scientists

From swab to sequencing - scalable method for identifying SARS-CoV-2

Study suggests new approach to make radiation therapy more effective for glioblastoma patients

Mice born with Fragile X syndrome have fewer cell antennas

Researchers to investigate real-world effects of new cystic fibrosis medications

Researchers identify targeted treatment strategy for malignant pleural mesothelioma

Researchers are developing comprehensive catalog of functional elements of human and mouse genomes

Partial loss of MYLPF gene can cause distal arthrogryposis, shows study

Relatives of SARS-CoV-2 may pose a health threat for years to come

Antioxidant-rich foods may increase risk for bowel cancers, study finds

UC San Diego researchers part of special package of human genome studies

Experts caution against routine use of current GEP tests for melanoma patients

Study finds fungal isolates with high levels of virulence in different hospitals

New maps of chemical marks on DNA could help illuminate the causes of developmental disorders

Study reveals mechanisms of mechanical stretch induced skin expansion

Study identifies novel function of SMS enzyme to facilitate colorectal cancer growth

Deep learning algorithm can identify genetic alterations from routine histological images of tumors

'Synthetic lethality' could be exploited for cancer therapy

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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