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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Magnets could be used for directing stem cells, may help treat heart and vascular diseases

Magnets could be a tool for directing stem cells' healing powers to treat conditions such as heart disease or vascular disease.

17 Jul 2013

Largest data set of cancer-specific genetic variations generated by NCI scientists

Scientists at the National Cancer Institute have generated a data set of cancer-specific genetic variations and are making these data available to the research community, according to a study published in Cancer Research, a journal of the American Association for Cancer Research.

16 Jul 2013

Discovery of hybrid cells in human melanoma

The University of Colorado Cancer Center along with Yale University and the Denver Crime Lab report in the journal PLOS ONE the first proof of cancer's ability to fuse with blood cells in a way that gives cancer the ability to travel, allowing previously stationary cancer cells to enter the bloodstream and seed sites of metastasis around the body.

16 Jul 2013

Law of physics can be demonstrated by collection of individual protein molecules

Experiments by biochemists at the University of California, Davis show for the first time that a law of physics, the ergodic theorem, can be demonstrated by a collection of individual protein molecules -- specifically, a protein that unwinds DNA. The work will be published online by the journal Nature on July 14.

16 Jul 2013

New application note describes ChIP assay technology for screening multiple epigenetic targets

Porvair Sciences has announced an application note describing the excellent results achievable from a new 96-well format version of its ChromaTrap chromatin immunoprecipitation assay technology.

From Chromatrap® - Porvair Sciences Ltd 16 Jul 2013

White blood cells and the spread of cancer: an interview with Drs. Lorenzo Ferri and Jonathan Cools-Lartigue, McGill University

As surgeons who take care of cancer patients, we have observed a troubling association between patients who suffer from infections after surgery and the rapid spread of their cancer. We have reported this in lung cancer patients, and others have made these observations in a variety of different cancers. However, the mechanisms responsible for this association are still poorly understood.

16 Jul 2013

CUMC researchers develop new approach to tailor cancer therapy for individual patient

Columbia University Medical Center (CUMC) researchers are developing a new approach to cancer clinical trials, in which therapies are designed and tested one patient at a time.

16 Jul 2013

Scientists discover how BRCA1 gene mutations predispose women to breast and ovarian cancers

Scientists led by Drs. Mona Gauthier and Tak Mak at The Campbell Family Institute for Breast Cancer Research at the Princess Margaret Cancer Centre have solved a key piece in the puzzle of how BRCA1 gene mutations specifically predispose women to breast and ovarian cancers.

16 Jul 2013

Proteins involved in immunity produce cancer-causing DNA mutations, study finds

A set of proteins involved in the body's natural defenses produces a large number of mutations in human DNA, according to a study led by researchers at the National Institutes of Health. The findings suggest that these naturally produced mutations are just as powerful as known cancer-causing agents in producing tumors.

15 Jul 2013

Cambridge Epigenetix introduces TrueMethyl kits for epigenetics industry

Cambridge Epigenetix Ltd., a spin out biosciences company, has announced the launch of its TrueMethyl kits.

15 Jul 2013

ADC Therapeutics, BZL Biologics sign licensing deal for antibody against PSMA-positive prostate cancers

ADC Therapeutics Sarl, a portfolio company of Auven Therapeutics and the oncology drug development company specializing in proprietary antibody drug conjugates, and BZL Biologics LLC, of New York, today announced an exclusive licensing and collaboration agreement for an antibody against PSMA-positive prostate cancers.

15 Jul 2013

FDA approves QIAGEN’s therascreen EGFR test as companion diagnostic for NSCLC patients

QIAGEN N.V. (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) today announced it has received approval by the U.S. Food and Drug Administration (FDA) to market the therascreen EGFR test as a companion diagnostic to guide the use of Boehringer Ingelheim's new targeted therapy, GILOTRIF™ (afatinib), for treatment of metastatic NSCLC in patients whose tumors have certain EGFR gene mutations.

From QIAGEN Manchester Limited 15 Jul 2013

Scientists discover new details of biochemical interactions necessary for cell division

Building on earlier work exploring the complex choreography by which intricate cellular proteins interact with and copy DNA prior to cell division, scientists at the U.S. Department of Energy's Brookhaven National Laboratory and collaborators have captured a key step-molecular images showing how the enzyme that unwinds the DNA double helix gets drawn to and wrapped around its target.

15 Jul 2013

High folate intake during pregnancy may have undiscovered later-life effect in progeny

During pregnancy, women are normally advised to take high amounts of multivitamin supplements. In particular, folate is recommended to reduce the risk of neural tube defects in newborns. The problem is that, although vitamins are critical in fetal development, high vitamin doses during pregnancy may cause undesired effects on the offspring later in life.

15 Jul 2013

New discovery reveals how RNA moves genetic information from DNA to create proteins

The discovery cracks the "RNA control code," which dictates how RNA - a family of molecules that mediates DNA expression - moves genetic information from DNA to create proteins.

15 Jul 2013

Researchers discover that APOBEC3B is important cancer mutagen

Researchers at the University of Minnesota have discovered that a human antiviral enzyme causes DNA mutations that lead to several forms of cancer.

15 Jul 2013

Genetic abnormality linked to cancer four times more common in people with type 2 diabetes

A type of genetic abnormality linked to cancer is more common in people with type 2 diabetes than the rest of the population, a new study has found.

15 Jul 2013

Genome sequencing promises to identify rare mutations that give rise to autism

An international consortium, consisting of Autism Speaks, Duke University School of Medicine, The Hospital for Sick Children of Toronto, BGI and other institutes, has investigated the genetic variants in 32 families with Autism Spectrum Disorder (ASD).

12 Jul 2013

General DNA sequencing can reveal previously undetectable viruses

There are 170 established HPV types. Cancerous human papillomavirus (HPV) viruses are the main cause of cervical cancer, and are found in close to 100% of cervical tumors.

12 Jul 2013

Hydrogel method form synthetic scaffolds to support formation of blood vessels in engineered tissues

Next-generation hydrogels can form synthetic scaffolds to support the formation of replacement tissues and organs in the emerging area of regenerative medicine. Embedding peptides into the hydrogels stimulates the growth of essential microvascular networks to ensure a good blood supply.

12 Jul 2013

DNA News and Research

Further Reading

Magnets could be used for directing stem cells, may help treat heart and vascular diseases

Largest data set of cancer-specific genetic variations generated by NCI scientists

Discovery of hybrid cells in human melanoma

Law of physics can be demonstrated by collection of individual protein molecules

New application note describes ChIP assay technology for screening multiple epigenetic targets

White blood cells and the spread of cancer: an interview with Drs. Lorenzo Ferri and Jonathan Cools-Lartigue, McGill University

CUMC researchers develop new approach to tailor cancer therapy for individual patient

Scientists discover how BRCA1 gene mutations predispose women to breast and ovarian cancers

Proteins involved in immunity produce cancer-causing DNA mutations, study finds

Cambridge Epigenetix introduces TrueMethyl kits for epigenetics industry

ADC Therapeutics, BZL Biologics sign licensing deal for antibody against PSMA-positive prostate cancers

FDA approves QIAGEN’s therascreen EGFR test as companion diagnostic for NSCLC patients

Scientists discover new details of biochemical interactions necessary for cell division

High folate intake during pregnancy may have undiscovered later-life effect in progeny

New discovery reveals how RNA moves genetic information from DNA to create proteins

Researchers discover that APOBEC3B is important cancer mutagen

Genetic abnormality linked to cancer four times more common in people with type 2 diabetes

Genome sequencing promises to identify rare mutations that give rise to autism

General DNA sequencing can reveal previously undetectable viruses

Hydrogel method form synthetic scaffolds to support formation of blood vessels in engineered tissues

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