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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Blocking the production of CHD4 protein may help increase effectiveness of AML treatments

Preclinical experiments led by a team of researchers at VCU Massey Cancer Center have shown that blocking the production of a protein known as chromodomain helicase DNA-binding protein 4 (CHD4) may help increase the effectiveness of first-line treatments for acute myeloid leukemia (AML), a particularly lethal blood cancer that is increasing in incidence among older adults.

14 Oct 2015

ASF launches Autism Sisters Project to accelerate research into 'Female Protective Effect'

The Autism Science Foundation, a not-for-profit organization dedicated to supporting and funding autism research, today announced the launch of the Autism Sisters Project, a new initiative that will give unaffected sisters of individuals with autism the opportunity to take an active role in accelerating research into the "Female Protective Effect."

14 Oct 2015

UCLA Health adopts GenomOncology's GO Clinical Workbench to accelerate analysis for tumor DNA profiling tests

GenomOncology today announced that UCLA Health has adopted the GO Clinical Workbench to accelerate analysis and reporting for its tumor DNA profiling tests.

13 Oct 2015

GENALICE’s Population Calling analysis module improves diagnosis, treatment of complex DNA diseases

Today, GENALICE is setting a new standard for ultra-fast and highly reliable detection of all DNA changes in large patient cohorts. In a one-hour online event, the complete genomes of 800 Alzheimer Disease (AD) patients were processed, and by ingeniously using the aggregate information from the complete group, detection of DNA changes, or variants, in individual patients was enhanced.

13 Oct 2015

Quest Diagnostics scientists demonstrate new molecular combing technique that predicts cystic fibrosis, muscular dystrophy

Genetic testing for mutations beyond those currently recommended in medical guidelines may aid the identification of more couples at risk of having a child with cystic fibrosis, according to a study presented today at the 2015 American Society of Human Genetics Annual Meeting, which runs through October 10 in Baltimore, Maryland.

From Quest Diagnostics 13 Oct 2015

GENALICE’s Population Calling analysis module improves diagnosis, treatment of complex DNA diseases

13 Oct 2015

ATA announces research grants to support projects proposed by young researchers

The American Thyroid Association is pleased to announce that grants have been awarded to support projects proposed by leading young researchers. Three of these projects involve the genetic analysis of thyroid tumors carrying the BRAFV600E mutation, which is associated with the development of some forms of thyroid cancer and increased risk for distant metastases, more advanced disease, and higher mortality.

13 Oct 2015

Tamoxifen drug clears MRSA, reduces mortality

Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have found that the breast cancer drug tamoxifen gives white blood cells a boost, better enabling them to respond to, ensnare and kill bacteria in laboratory experiments. Tamoxifen treatment in mice also enhances clearance of the antibiotic-resistant bacterial pathogen MRSA and reduces mortality.

13 Oct 2015

Penn researchers lay groundwork for developing lncRNA-based tools for new cancer treatment

Growing insights about a significant, yet poorly understood, part of the genome - the "dark matter of DNA" -- have fundamentally changed the way scientists approach the study of diseases.

13 Oct 2015

Prostate Cells Undergo 'Reprogramming' To Form Tumors, Study Finds

Scientists have gained a key insight into how prostate tumors get their start - not by rewriting the normal DNA code, but by reprogramming the master regulator of genes in prostate cells to drive malignant growth.

12 Oct 2015

Study identifies four distinct types of bowel cancer

Bowel cancer can be divided up into four distinct diseases, each with its own set of biological characteristics, a major new study reports.

12 Oct 2015

Researchers reveal that supercoiled DNA's shape more dynamic than well-known double helix

Researchers have imaged in unprecedented detail the three-dimensional structure of supercoiled DNA, revealing that its shape is much more dynamic than the well-known double helix.

12 Oct 2015

Sequenom signs clinical collaboration with University Medical Center Hamburg-Eppendorf

Sequenom, Inc., a life sciences company committed to enabling healthier lives through the development of innovative products and services, today announced that it has entered into a clinical collaboration with University Medical Center Hamburg-Eppendorf (UKE) in Germany.

12 Oct 2015

Researchers reveal 3-D structure of biologically active DNA

Using a multidisciplinary approach, researchers, led by those at Baylor College of Medicine, revealed in unprecedented detail the three-dimensional structure of biologically active DNA. A report on their work appears online in the journal Nature Communications.

12 Oct 2015

UV robots help reduce rates of C. diff transmission among cancer inpatients

Robots are capable of all sorts of tasks to help better treat cancer: They connect oncologists to patients remotely, make incisions, staple them shut, deliver "nano" therapies--and they clean rooms. New research from Penn Medicine infection control specialists found that ultraviolet (UV) robots helped reduce the rates transmission of the common bacterial infection known as Clostridium difficile among cancer inpatients - mostly blood cancer patients, a group more vulnerable to hospital-acquired infections - by 25 percent. The interventions also saved about $150,000 in annual direct medical costs.

12 Oct 2015

UConn researchers sequence RNA of most complicated gene

UConn researchers have sequenced the RNA of the most complicated gene known in nature, using a hand-held sequencer no bigger than a cell phone.

From Oxford Nanopore Technologies 12 Oct 2015

Role for endogenous retrovirus proposed in ALS pathogenesis

Expression of the human endogenous retrovirus-K is upregulated in some patients with sporadic amyotrophic lateral sclerosis and causes degeneration of motor neurons when overexpressed in mice, research shows.

9 Oct 2015

Scientists can now use skin samples from older patients to grow brain cells

For the first time, scientists can use skin samples from older patients to create brain cells without rolling back the youthfulness clock in the cells first. The new technique, which yields cells resembling those found in older people's brains, will be a boon to scientists studying age-related diseases like Alzheimer's and Parkinson's.

9 Oct 2015

Scientists engineer stem cells to better understand mechanisms behind leukemia

Scientists engineered stem cells to better understand the mechanisms behind a form of leukemia caused by changes in a key gene, according to a study led by Mount Sinai researchers and published online today in the journal Cell Reports.

9 Oct 2015

Proposed thin-plate model sheds light on structural basis of chromosomal aberrations in cancer cells

During cell division, each metaphase chromosome contains a single enormously long DNA molecule that is associated with histone proteins and forms a long chromatin filament with many nucleosomes.

9 Oct 2015

DNA News and Research

Further Reading

Blocking the production of CHD4 protein may help increase effectiveness of AML treatments

ASF launches Autism Sisters Project to accelerate research into 'Female Protective Effect'

UCLA Health adopts GenomOncology's GO Clinical Workbench to accelerate analysis for tumor DNA profiling tests

GENALICE’s Population Calling analysis module improves diagnosis, treatment of complex DNA diseases

Quest Diagnostics scientists demonstrate new molecular combing technique that predicts cystic fibrosis, muscular dystrophy

GENALICE’s Population Calling analysis module improves diagnosis, treatment of complex DNA diseases

ATA announces research grants to support projects proposed by young researchers

Tamoxifen drug clears MRSA, reduces mortality

Penn researchers lay groundwork for developing lncRNA-based tools for new cancer treatment

Prostate Cells Undergo 'Reprogramming' To Form Tumors, Study Finds

Study identifies four distinct types of bowel cancer

Researchers reveal that supercoiled DNA's shape more dynamic than well-known double helix

Sequenom signs clinical collaboration with University Medical Center Hamburg-Eppendorf

Researchers reveal 3-D structure of biologically active DNA

UV robots help reduce rates of C. diff transmission among cancer inpatients

UConn researchers sequence RNA of most complicated gene

Role for endogenous retrovirus proposed in ALS pathogenesis

Scientists can now use skin samples from older patients to grow brain cells

Scientists engineer stem cells to better understand mechanisms behind leukemia

Proposed thin-plate model sheds light on structural basis of chromosomal aberrations in cancer cells

Understanding the DNA Damage Response in Innate Immunity eBook

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