Immune System News and Research

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Findings suggest potential metabolic pathway against cancer

When cancer cells compete with immune cells for glucose, the cancer wins. As a result, the immune T cells are not healthy and don't have the weapons to kill the cancer.

3 Nov 2015

Study highlights importance of sex-specific differences in complex biological processes

New research published in the Journal of Leukocyte Biology shows that male and female mice respond differently to inflammation at the cellular level. Specifically, in male mice the spleen acts as a source of white blood cells, while in females this is not the case. This discovery suggests that human studies are necessary to determine if current medical practices, which treat men and women generally the same, should be altered to reflect sex-specific differences.

3 Nov 2015

Small subtype of immune cells appears to prevent obesity

We tend to think of the immune system as guarding us against bacteria, viruses and assorted foreign invaders, but this system has some other surprising roles. Weizmann Institute researchers have now identified a small subtype of immune cells that appears to prevent metabolic syndrome: obesity, high blood pressure, and high levels of blood sugar and cholesterol.

3 Nov 2015

United Cannabis files utility and PCT patent applications related to unique specifications of cannabinoids

United Cannabis Corporation today announced that it moved its provisional patent application to the next phase by filing a utility patent application related to the unique combinations of pharmaceutically active cannabinoids used to treat disorders of the nervous system, immune system and cancer with the U.S. Patent and Trademark Office.

3 Nov 2015

New initiative launched to accelerate search for effective HIV vaccine

A new 23 million euro initiative to accelerate the search for an effective HIV vaccine begins today. Financed by the European Commission, the European AIDS Vaccine Initiative (EAVI2020) brings together leading HIV researchers from public organisations and biotech companies from across Europe, Australia, Canada and the USA in a focused effort to develop protective and therapeutic HIV vaccines.

2 Nov 2015

Unique funding opportunity seeks countermeasures to protect healthy tissue from radiation exposure

Small U.S.-based companies developing countermeasures to protect healthy tissue from the effects of radiation exposures may be eligible for a unique funding opportunity offered through the National Space Biomedical Research Institute. NSBRI's Industry Forum is soliciting applications for its Space Medical and Related Technologies Commercialization Assistance Program (SMARTCAP).

31 Oct 2015

Resistance to CD19 CAR T-cell therapy can be caused by CD19 splicing alterations

Resistance to CD19 CAR T-cell therapy, a type of immunotherapy that yields long-lasting remissions in many patients with B-cell leukemia, can be caused by CD19 splicing alterations, leading to loss of certain parts of the CD19 protein that are recognized by the CAR T cells.

31 Oct 2015

New research may offer strategies for developing toxoplasma-inactivated vaccine

Toxoplasma gondii is a common parasite which causes the development of fatal encephalosis or pneumonia in immunodeficient patients under treatment of AIDS or cancer.

31 Oct 2015

Blocking calcium-signaling pathway could inhibit Ebola virus and other sources of deadly infections

The Ebola virus acts fast. The course of infection, from exposure to recovery, or death, can take as little as two weeks. That may not leave enough time for the immune system to mount an effective response.

31 Oct 2015

Researchers discover key regulator that impacts survival of lymphoma patients

An important regulator that controls the ability of tumour cells to hide from the immune system in lymphoma patients, making them unlikely to respond to standard treatment, has been discovered by scientists at the University of Oxford.

31 Oct 2015

ISCT launches publication and reference guide on Use of Unproven Cellular Therapies

The International Society for Cellular Therapy, the global society of clinicians, researchers, regulators, technologists, and industry partners dedicated to the translation of cellular therapy into safe and effective therapies to improve patients’ lives, today announces the launch of its publication and reference guide on the Use of Unproven Cellular Therapies.

31 Oct 2015

Stem cell transplantation may offer viable treatment for Alzheimer's disease patients

Alzheimer's disease (AD), affecting millions worldwide, is the leading cause of dementia. The prevalence of AD is rapidly increasing, and will possibly affect over 100 million people by 2050, yet there are no effective therapies for the disease.

31 Oct 2015

UTMB scientists work with InBios International to develop novel diagnostic test for chikungunya

A novel and affordable diagnostic test for chikungunya will soon be available thanks to the work of researchers at the University of Texas Medical Branch at Galveston in partnership with a commercial lab.

30 Oct 2015

Physicians leave severe acne patients on ineffective antibiotics for too long before prescribing more potent drug

A medical records analysis by researchers at NYU Langone Medical Center concludes that physicians who treat severe acne leave too many patients on ineffective antibiotics for far too long before prescribing more potent needed therapy with the medication isotretinoin, sometimes known by its former brand name Accutane.

30 Oct 2015

Specialized type of immunotherapy can boost survival from pancreatic cancer

A new study in mice by researchers at Fred Hutchinson Cancer Research Center has found that a specialized type of immunotherapy — even when used without chemotherapy or radiation — can boost survival from pancreatic cancer, a nearly almost-lethal disease, by more than 75 percent. The findings are so promising, human clinical trials are planned within the next year.

30 Oct 2015

Gut bacteria may increase risk of metabolic syndrome

An excess of bacteria in the gut can change the way the liver processes fat and could lead to the development of metabolic syndrome, according to health researchers.

30 Oct 2015

Basic research for developing toxoplasma vaccine underway

Toxoplasma gondii is a common parasite which causes the development of fatal encephalosis or pneumonia in immunodeficient patients under treatment of AIDS or cancer. Pregnant women who are infected may suffer a miscarriage or the newborn child may suffer from a congenital disease. Currently, a toxoplasma vaccine for humans is not available. Using experimental animals such as mice, basic research for developing an inactivated vaccine is underway.

30 Oct 2015

Scientists one step closer to developing new treatment for inflammatory bowel disease

For patients with inflammatory bowel disease, the possibility of taking a single pill to bring long-lasting relief might seem too good to be true. Scientists at the Lewis Katz School of Medicine at Temple University are on the brink of making that happen, thanks to a recent proof-of-concept study, in which the severity of a form of inflammatory bowel disease in mice was dramatically reduced with one oral dose of a protein isolated from a bacterial biofilm.

30 Oct 2015

SLU VTEU awarded $5.8 million NIH contract to support 'omics' research initiative

Saint Louis University's Vaccine and Treatment Evaluation Unit has received a five-year, $5.8 million contract from the National Institutes of Health to support an "omics" research initiative to study the safety and effectiveness of vaccines and other ways to fight infectious diseases.

30 Oct 2015

Adelaide researchers identify key protein involved in 'super-inflammatory' immune response

Researchers have made another important step in the progress towards being able to block the development of multiple sclerosis (MS) and other autoimmune diseases.

29 Oct 2015

Immune System News and Research

Findings suggest potential metabolic pathway against cancer

Study highlights importance of sex-specific differences in complex biological processes

Small subtype of immune cells appears to prevent obesity

United Cannabis files utility and PCT patent applications related to unique specifications of cannabinoids

New initiative launched to accelerate search for effective HIV vaccine

Unique funding opportunity seeks countermeasures to protect healthy tissue from radiation exposure

Resistance to CD19 CAR T-cell therapy can be caused by CD19 splicing alterations

New research may offer strategies for developing toxoplasma-inactivated vaccine

Blocking calcium-signaling pathway could inhibit Ebola virus and other sources of deadly infections

Researchers discover key regulator that impacts survival of lymphoma patients

ISCT launches publication and reference guide on Use of Unproven Cellular Therapies

Stem cell transplantation may offer viable treatment for Alzheimer's disease patients

UTMB scientists work with InBios International to develop novel diagnostic test for chikungunya

Physicians leave severe acne patients on ineffective antibiotics for too long before prescribing more potent drug

Specialized type of immunotherapy can boost survival from pancreatic cancer

Gut bacteria may increase risk of metabolic syndrome

Basic research for developing toxoplasma vaccine underway

Scientists one step closer to developing new treatment for inflammatory bowel disease

SLU VTEU awarded $5.8 million NIH contract to support 'omics' research initiative

Adelaide researchers identify key protein involved in 'super-inflammatory' immune response

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