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PTC299 inhibits SARS-CoV-2 replication and suppresses production of inflammatory cytokines

In an article published in the journal Virus Research, a team of researchers from various US institutions discussed their study that evaluated the antiviral activity of PTC299 against a group of RNA viruses in vitro.

1 Dec 2020

More than 40 Dana-Farber studies to be presented at the virtual 62nd ASH Annual Meeting

Dana-Farber Cancer Institute researchers will present more than 40 research studies at the virtual 62nd American Society of Hematology Annual Meeting on December 5-8, including two studies that were selected for inclusion in the official press program.

1 Dec 2020

Nanomedicine's giant step into the fight against the COVID-19

A recent editorial in Nature Nanotechnology discusses the enormous feat of scientific innovation, with messenger RNA (mRNA)-based vaccines developed to deliver the gene sequence of specific SARS-CoV-2 viral proteins into host cells using nanotechnology platforms.

1 Dec 2020

First PSMA-targeted PET imaging drug approved for men with prostate cancer

Today, the U.S. Food and Drug Administration approved Gallium 68 PSMA-11 (Ga 68 PSMA-11) - the first drug for positron emission tomography (PET) imaging of prostate-specific membrane antigen (PSMA) positive lesions in men with prostate cancer.

1 Dec 2020

Study uncovers a promising therapeutic target for retinal dystrophies

A team of LSU Health New Orleans researchers reports for the first time that deleting one of the inhibitors of the RPE65 gene in a mouse model that carries a human disease mutation prevents degeneration of cone photoreceptors that are used for daytime high-resolution color vision.

1 Dec 2020

Mayo Clinic study identifies trends in statin use across the U.S.

People who have coronary artery disease, stroke or peripheral artery disease often are prescribed a statin, a cholesterol-lowering drug that reduces the risk of heart attack or stroke.

1 Dec 2020

HIV 'wonder drug' may not be as effective as hoped in sub-Saharan Africa, study suggests

Dolutegravir, the current first-line treatment for HIV, may not be as effective as hoped in sub-Saharan Africa, suggests new research published on World AIDS Day. The study finds that this so-called 'wonder drug' may be less effective in patients resistant to older drugs.

1 Dec 2020

Experimental drug can reverse age-related memory decline in mice

Just a few doses of an experimental drug can reverse age-related declines in memory and mental flexibility in mice, according to a new study by UC San Francisco scientists.

1 Dec 2020

Amid COVID and racial unrest, Black churches put faith in mental health care

Wilma Mayfield used to visit a senior center in Durham, North Carolina, four days a week and attend Lincoln Memorial Baptist Church on Sundays, a ritual she's maintained for nearly half a century. But over the past 10 months, she's seen only the inside of her home, the grocery store and the pharmacy.

1 Dec 2020

Researchers show strong link between Takotsubo syndrome and impaired thyroid function

Researchers have found a new hypothesis for explaining Takotsubo cardiomyopathy, also known as broken heart syndrome.

1 Dec 2020

Machine learning model identifies which drug combinations kill tumor cells

When healthcare professionals treat patients suffering from advanced cancers, they usually need to use a combination of different therapies. In addition to cancer surgery, the patients are often treated with radiation therapy, medication, or both.

1 Dec 2020

Chinese woman still sheds SARS-CoV-2 over four months post-infection

A new study by Chinese scientists explore an unusual case of extended viral shedding in a 68-year-old woman up to four months post-infection.

1 Dec 2020

Experimental stem cell gene therapy may give a new lease of life for patient with sickle cell disease

"But it's a marathon whereas you keep going, the trail gets rockier and then you lose your shoes," the 27-year-old said. "It gets harder as you get older. Things start to fail and all you can think about is how much worse it's going to get down the road."

1 Dec 2020

Gut microbiota directly shapes the makeup of human immune system, shows study

MSK researchers have uncovered an important finding about the relationship between the microbiota and the immune system, showing for the first time that the concentration of different types of immune cells in the blood changes in relation to the presence of different bacterial strains in the gut.

1 Dec 2020

Chloroquine/hydroxychloroquine could treat COVID-19 infection

The recent serious outbreak of Covid19 has affected (November 13, 2020) 53,796,098 people worldwide, resulting in 37,555,669 recovered, 1,310,250 deaths, and a large number of open cases.

1 Dec 2020

SEAR implemented measures for successful continuation of essential HIV services during COVID 19

The COVID-19 pandemic was predicted to and has had a major impact on the essential HIV health services in the South East Asia Region (SEAR), putting at risk the benefits accrued over the last two decades. Apart from the risks posed by the virus to the individual health of people living with HIV (PLHIV), COVID-19 has disrupted essential services causing considerable delays in the delivery of medicines and other health commodities.

1 Dec 2020

Researchers successfully edit SIV virus from genomes of non-human primates

Taking a major step forward in HIV research, scientists at the Lewis Katz School of Medicine at Temple University have successfully edited SIV - a virus closely related to HIV, the cause of AIDS - from the genomes of non-human primates.

1 Dec 2020

Study demonstrates safety of novel immuno-oncology therapy in patients with advanced solid tumors

A novel therapy designed to help stimulate the body's immune system response against cancer appears to be safe to use as alone or in combination with immune checkpoint inhibitors.

1 Dec 2020

Cost of prostate cancer treatment can be a major source of stress for men, their families

For men with early-stage prostate cancer, choices about initial treatment carry varying risks of "financial toxicity," reports a study in The Journal of Urology®, Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.

1 Dec 2020

Clonal hematopoiesis linked to severe COVID-19

Now, an international team of researchers from the USA, South Korea and Canada has found that clonal hematopoiesis is tied to the risk of severe COVID-19.

30 Nov 2020

Therapy News and Research

PTC299 inhibits SARS-CoV-2 replication and suppresses production of inflammatory cytokines

More than 40 Dana-Farber studies to be presented at the virtual 62nd ASH Annual Meeting

Nanomedicine's giant step into the fight against the COVID-19

First PSMA-targeted PET imaging drug approved for men with prostate cancer

Study uncovers a promising therapeutic target for retinal dystrophies

Mayo Clinic study identifies trends in statin use across the U.S.

HIV 'wonder drug' may not be as effective as hoped in sub-Saharan Africa, study suggests

Experimental drug can reverse age-related memory decline in mice

Amid COVID and racial unrest, Black churches put faith in mental health care

Researchers show strong link between Takotsubo syndrome and impaired thyroid function

Machine learning model identifies which drug combinations kill tumor cells

Chinese woman still sheds SARS-CoV-2 over four months post-infection

Experimental stem cell gene therapy may give a new lease of life for patient with sickle cell disease

Gut microbiota directly shapes the makeup of human immune system, shows study

Chloroquine/hydroxychloroquine could treat COVID-19 infection

SEAR implemented measures for successful continuation of essential HIV services during COVID 19

Researchers successfully edit SIV virus from genomes of non-human primates

Study demonstrates safety of novel immuno-oncology therapy in patients with advanced solid tumors

Cost of prostate cancer treatment can be a major source of stress for men, their families

Clonal hematopoiesis linked to severe COVID-19

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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