Research News and Research

RSS

Janssen submits sNDA to FDA for simeprevir in combination with sofosbuvir for treatment of HCV genotype 1 infection

Janssen Research & Development, LLC (Janssen) today announced it has submitted a Supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for simeprevir, an NS3/4A protease inhibitor marketed as OLYSIO™ in the United States, in combination with the nucleotide analog NS5B polymerase inhibitor sofosbuvir developed by Gilead Sciences, Inc.

8 May 2014

NIH-funded study in tanzanian infants tracked risk of severe malaria over time

Although malaria kills some 600,000 African children each year, most cases of the mosquito-borne parasitic disease in children are mild.

8 May 2014

Smartphone app shows promise for detecting early signs of mood changes in people with bipolar disorder

A smartphone app that monitors subtle qualities of a person's voice during everyday phone conversations shows promise for detecting early signs of mood changes in people with bipolar disorder, a University of Michigan team reports.

8 May 2014

TAG-1 induces apoptosis-related gene expression without triggering apoptosis in glioma cells

A recent study reported by Haigang Chang and co-workers from the First Affiliated Hospital of Xinxiang Medical University in China verified the effects of transient axonal glycoprotein-1 (TAG-1) on cell viability and p53, epidermal growth factor receptor (EGFR), and amyloid precursor protein (APP) intracellular C-terminal domain (AICD) expression in U251 glioma cells.

8 May 2014

Study encourages schools to be more aware of hand-washing

Dr. Michael Gabriel of GPM Pediatrics, a New York based Pediatric Center, comments on an article that says children are more likely to wash their hands when someone is around or watching. This new study could prove to be useful in reducing the amount of infectious diseases contracted by children.

8 May 2014

Leica and Affymetrix launch fully automated RNA in situ hybridization assays

Affymetrix, Inc. (NASDAQ:AFFX) and Leica Biosystems announce the launch of Affymetrix' fully automated RNA in situ hybridization assays ViewRNATM eZ Assays on the Leica BOND RX staining platform.

8 May 2014

Shuganjieyu capsule reverses depressive behaviors by increasing brain-derived neurotrophic factor

Shuganjieyu capsule has been approved for clinical treatment by the State Food and Drug Administration of China since 2008.

8 May 2014

RAAV/ABAD-DP-6His generates fusion peptide that protects PC12 cells from oxidative stress injury

The effects of Amyloid beta (Aβ)-Aβ-binding alcohol dehydrogenase (ABAD) may exacerbate Alzheimer's disease pathology.

8 May 2014

Johns Hopkins launches Global Health NOW news email for serving global health community

The Johns Hopkins Bloomberg School of Public Health is announcing the launch of Global Health NOW, an aggregated news email serving the global health community. Delivered every weekday morning, Global Health NOW summarizes the day's essential news articles and commentaries from around the world.

8 May 2014

Researchers to develop unique technology to help physicians perform ultrasound-guided procedures involving needle placement

Significant funding from NIBIB has enabled researchers to develop a unique technology to help physicians perform ultrasound-guided procedures involving needle placement such as needle biopsies, central line insertion, and local anesthesia.

8 May 2014

New device to monitor voice professionals and track vocal changes

A new device to monitor voice professionals as well as to track vocal changes that are due to chronic diseases and physical or psychological stress

8 May 2014

WHI: Combined hormone therapy clinical trial yields massive economic return

Economic findings were released today on the Women's Health Initiative (WHI), estrogen plus progestin (E+P) trial.

8 May 2014

First international molecular screening program at IMPAKT for metastatic breast cancer

While research has made great strides in recent decades to improve and significantly extend the lives of patients with early breast cancer, the needs of patients with advanced or metastatic disease have largely been ignored.

8 May 2014

State highlights: SEIU, hospital strike deal in Calif.; N.Y. Medicaid audit; dental therapists

A selection of health policy stories from California, New York, Connecticut, Georgia, Indiana and North Carolina.

8 May 2014

Commonly used drug restores blood flow to oxygen-starved muscles of boys with muscular dystrophy

Cedars-Sinai Heart Institute researchers have found that a commonly prescribed drug restores blood flow to oxygen-starved muscles of boys with Duchenne muscular dystrophy, a genetic muscle-wasting disease that rarely is seen in girls but affects one in 3,500 male babies, profoundly shortening life expectancy. It is the most common fatal disease that affects children.

8 May 2014

Children's Hospital Los Angeles receives $3M from Simms/Mann Family Foundation

The Simms/Mann Family Foundation has made a $3 million gift to Children's Hospital Los Angeles to fund an endowed chair for the director of the Developmental Neurogenetics program within CHLA's Institute for the Developing Mind.

8 May 2014

Study: Elevated levels of atmospheric CO2 threaten human nutrition

At the elevated levels of atmospheric CO2 anticipated by around 2050, crops that provide a large share of the global population with most of their dietary zinc and iron will have significantly reduced concentrations of those nutrients, according to a new study led by Harvard School of Public Health (HSPH).

8 May 2014

Viewpoints: Evidence for Obamacare saving lives; a continuing role for Minnesotacare

People asking the ultimate question about the Affordable Care Act--will it actually save lives?--now have an answer, and it's yes.

8 May 2014

Research may have "major implications" for treatment of urinary tract infections in children

A major new pediatric research study led by a Wayne State University researcher, funded by the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health (NIH) and published this week in the New England Journal of Medicine (NEJM), has "major implications" for the treatment of urinary tract infections (UTIs) in millions of American children.

8 May 2014

Dose-tracking software provides easy monitoring of radiation dose exposure in academic practice

Dose-tracking software provides effective and easy monitoring of radiation dose exposure in a busy academic practice, according to research conducted at Massachusetts General Hospital.

8 May 2014

Research News and Research

Janssen submits sNDA to FDA for simeprevir in combination with sofosbuvir for treatment of HCV genotype 1 infection

NIH-funded study in tanzanian infants tracked risk of severe malaria over time

Smartphone app shows promise for detecting early signs of mood changes in people with bipolar disorder

TAG-1 induces apoptosis-related gene expression without triggering apoptosis in glioma cells

Study encourages schools to be more aware of hand-washing

Leica and Affymetrix launch fully automated RNA in situ hybridization assays

Shuganjieyu capsule reverses depressive behaviors by increasing brain-derived neurotrophic factor

RAAV/ABAD-DP-6His generates fusion peptide that protects PC12 cells from oxidative stress injury

Johns Hopkins launches Global Health NOW news email for serving global health community

Researchers to develop unique technology to help physicians perform ultrasound-guided procedures involving needle placement

New device to monitor voice professionals and track vocal changes

WHI: Combined hormone therapy clinical trial yields massive economic return

First international molecular screening program at IMPAKT for metastatic breast cancer

State highlights: SEIU, hospital strike deal in Calif.; N.Y. Medicaid audit; dental therapists

Commonly used drug restores blood flow to oxygen-starved muscles of boys with muscular dystrophy

Children's Hospital Los Angeles receives $3M from Simms/Mann Family Foundation

Study: Elevated levels of atmospheric CO2 threaten human nutrition

Viewpoints: Evidence for Obamacare saving lives; a continuing role for Minnesotacare

Research may have "major implications" for treatment of urinary tract infections in children

Dose-tracking software provides easy monitoring of radiation dose exposure in academic practice

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Latest eBooks

Editorial Focus eBook - Proteomics (2nd Edition)

Industry Focus eBook - Life Science Microscopy (2nd Edition)

BFEB: Advances in microplate-based assays and analysis

Biologics stability screening toolkit: Three practical workflows for accelerating formulation development

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy