Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Researchers identify exosomes as missing link to insulin resistance in type 2 diabetes

Chronic tissue inflammation resulting from obesity is an underlying cause of insulin resistance and type 2 diabetes. But the mechanism by which this occurs has remained cloaked, until now.

21 Sep 2017

Physical stress in preemies plus separation from mothers may have lasting effects into adulthood

A new study suggests that physiological stress in premature infants combined with separation from their mothers may have lasting effects into adulthood.

20 Sep 2017

Researchers identify natural protective factor against chronic inflammation in diabetes patients

In type 2 diabetes, chronic inflammation drives cardiovascular disease, the leading cause of death among people with the condition. Researchers at Joslin Diabetes Center now have identified an unexpected natural protective factor that works against this inflammation.

20 Sep 2017

Link between breast cancer and obesity may be more complex than previously thought

Obese women with large bellies may be at risk of developing a different subtype of breast cancer than those with widespread fat accumulation, according to a new study published in The Oncologist. This suggests that the link between breast cancer and obesity may be more complex than previously thought.

18 Sep 2017

Study examines effects of poor sleep on progression of chronic kidney disease

People with chronic kidney disease may be especially vulnerable to the deleterious effects of poor sleep, according to a new paper published in the Journal of the American Society of Nephrology.

15 Sep 2017

Study uncovers how inflammation contributes to key feature of diabetes

A new study by researchers at the University of Maryland School of Medicine has uncovered how inflammation contributes to a key feature of diabetes, the body's inability to metabolize glucose, a condition known as insulin resistance.

12 Sep 2017

Abdominal weight found to be key predictor of cancer risk in postmenopausal women

Body fat distribution in the trunk is more important than body weight when it comes to cancer risk in postmenopausal women, according to a study presented at the ESMO 2017 Congress in Madrid.

11 Sep 2017

Researchers find signaling pathway in cells that plays key role in development of fatty liver disease

Morbid obesity affects the liver: Almost one-third of all adults suffer from chronic fatty liver disease, which can lead to infections and even trigger cancer. Researchers at the University Children's Hospital Zurich and the University of Zurich have now found a signaling pathway in cells that play an important role in the development of fatty liver disease.

7 Sep 2017

New technology-based approach could help identify people at high risk of type 2 diabetes

Researchers at the University of Glasgow have announced a new technology-based approach that could lead to a more accurate identification of people at high risk of type 2 diabetes.

1 Sep 2017

Bioinformatics expert receives $12.8 million grant to continue to lead Diabetic Complications Consortium

Dr. Richard A. McIndoe, bioinformatics expert and associate director of the Center for Biotechnology and Genomic Medicine at the Medical College of Georgia at Augusta University, has received a $12.8 million grant to continue to lead a national research initiative focused on reducing the complications of diabetes.

26 Aug 2017

Enhanced levels of NPs in adipose tissue protect against obesity and insulin resistance

Researchers at Sanford Burnham Prebys Medical Discovery Institute in Lake Nona, Florida have shown that enhanced natriuretic peptide (NP) signaling in adipose tissue protects against obesity and insulin resistance.

26 Aug 2017

Increased enzyme production by the liver causes fatty liver, obesity and insulin resistance

In mice that are given a high-fat diet, an increased production of the enzyme DPP4 by the liver promotes an increase in body fat, the development of fatty liver disease and insulin resistance.

24 Aug 2017

Studies aim to better understand potential health benefits of red raspberries

Initial findings from several studies - including both human subjects and animals - on the potential health benefits of red raspberries were presented earlier this year at the 2017 Experimental Biology conference in Chicago.

24 Aug 2017

Shorter sleep duration in childhood linked to higher risk of type 2 diabetes

A study has found that children who slept on average one hour less a night had higher risk factors for type 2 diabetes, including higher levels of blood glucose and insulin resistance.

16 Aug 2017

Poor sleep in children linked to development of diabetes later in life

A latest UK study has found that deficiency of adequate sleep in children could be linked to their risk of developing diabetes later in life. The study notes that every extra hour of sleep a child gets per night is associated with a lower body weight and increased lean muscle mass and less blood sugar. The study is published this week in the journal Pediatrics.

15 Aug 2017

SBIR Fast-Track grant to fund study on new drug that targets cardiovascular diseases

The Exscien Corporation of Louisville, KY, in conjunction with LSU Health New Orleans Cardiovascular Center of Excellence, has been awarded an SBIR Fast-Track grant in the amount of $3.7 million over three years by the National Heart, Lung and Blood Institute.

14 Aug 2017

Gene-therapy administered through skin transplants could enable treatment of many diseases

A research team based at the University of Chicago has overcome challenges that have limited gene therapy and demonstrated how their novel approach with skin transplantation could enable a wide range of gene-based therapies to treat many human diseases.

3 Aug 2017

Researchers highlight role of micro-guests in pathologic processes

We host more microbiota than our own cells. These micro-guests produce metabolites that are only beginning to be appreciated as important factors in pathologic processes, from chronic inflammatory diseases to preterm birth.

1 Aug 2017

Green tea component could alleviate insulin resistance, obesity, and cognitive impairment

A study published online in The FASEB Journal, involving mice, suggests that EGCG (epigallocatechin-3-gallate), the most abundant catechin and biologically active component in green tea, could alleviate high-fat and high-fructose (HFFD)-induced insulin resistance and cognitive impairment.

28 Jul 2017

Research shows alarming prevalence of overfat pandemic in developed countries

Does your waist measure more than half your height? If so, you may be part of the global overfat pandemic.

24 Jul 2017