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Untreated high blood pressure linked to higher Alzheimer's risk in older adults

People 60 and older with untreated high blood pressure may have an increased risk of Alzheimer's disease compared to both people who have been or are being treated for high blood pressure as well as people without the chronic condition.

14 Aug 2024

Experimental malaria vaccine shows promise in protecting pregnant women

Two National Institutes of Health (NIH)-supported trials of an experimental malaria vaccine in healthy Malian adults found that all three tested regimens were safe.

14 Aug 2024

Breakthrough in understanding cell communication during inflammation

Indiana University School of Medicine researchers have made significant progress in understanding how cells communicate during inflammation.

14 Aug 2024

Discovery of immune cell regulator could lead to new therapies for inflammatory conditions

The discovery of a new regulator affecting immune cells could lead to new treatments to reduce inflammation in diseases including arthritis and severe COVID 19.

14 Aug 2024

Early detection key to beating ovarian cancer

'Symptom triggered testing', prompted by symptoms such as pain, abdominal bloating/swelling, and feeling full soon after starting to eat, can pick up early stage aggressive ovarian cancer in 1 in 4 of those affected, finds a data analysis, published online in the International Journal of Gynecological Cancer.

14 Aug 2024

Researchers discover a novel pathway to wake up dormant neural stem cells

Scientists from Duke-NUS Medical School and the Mechanobiology Institute (MBI) at the National University of Singapore (NUS) have discovered a novel pathway to wake up dormant neural stem cells, offering potential new therapies for neurodevelopmental disorders such as autism, learning disabilities, and cerebral palsy.

13 Aug 2024

Largest multi-omics study identifies new genetic landscapes in colorectal cancer

The Institute of Intelligent Medical Research (IIMR) of BGI Genomics, in collaboration with Sweden's Uppsala University, has published the largest multi-omics study of colorectal cancer (CRC) to date.

13 Aug 2024

Mrc1 protein identified as key to maintaining cell identity during division

In a major scientific breakthrough, researchers have found that a protein called Mrc1 plays a crucial role in ensuring that cells keep their identity as they divide and grow.

13 Aug 2024

World's first rapid TBI blood test debuts at Orlando Health

Orlando Health Orlando Regional Medical Center (ORMC) is the first hospital in the world to use a new, groundbreaking blood test to help assess patients with suspected mild traumatic brain injuries (TBIs), or concussions.

13 Aug 2024

IU research sheds light on urea cycle defects and fatty liver disease

An Indiana University School of Medicine physician scientist is making strides in understanding the molecular origins of fatty liver disease, a leading cause of liver failure in the United States.

13 Aug 2024

NIH study finds routine lab tests fall short in diagnosing long COVID

A National Institutes of Health (NIH)-supported study has found that routine lab tests may not be useful in making a long COVID diagnosis for people who have symptoms of the condition

12 Aug 2024

Study uncovers OLAH as key driver of fatal respiratory disease

Respiratory infections can be severe, even deadly, in some individuals, but not in others.

12 Aug 2024

New breast cell atlas sheds light on genetic ancestry's role in cancer development

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have completed the most extensive mapping of healthy breast cells to date.

12 Aug 2024

Many children with recurrent wheezing have "silent" lung infections, research reveals

Nearly a quarter of children with recurrent wheezing have "silent" lung infections that would be better treated with antiviral medications than commonly prescribed steroids that can carry lifelong side effects, new research from the University of Virginia School of Medicine reveals.

8 Aug 2024

Polycystic ovary syndrome linked to greater risk of disordered eating in women

Women with the common reproductive and metabolic condition polycystic ovary syndrome (PCOS) face a greater risk of developing bulimia, binge eating disorder and disordered eating, according to new research published in The Journal of Clinical Endocrinology & Metabolism.

8 Aug 2024

Olympic games could fuel spread of tropical diseases, warn health experts

Mosquito-borne diseases such as dengue, Zika, and chikungunya could spread via the Olympics to countries where they are not normally prevalent, warn global health experts, as authorities step up disease monitoring in the French capital.

7 Aug 2024

NIH study reveals racial and gender disparities in survival rates from bystander CPR

A National Institutes of Health (NIH)-supported study has found race- and sex-based differences in the increased chances of survival from people who received bystander cardiopulmonary resuscitation (CPR) for out-of-hospital cardiac arrest.

7 Aug 2024

Study advances understanding of complex neurological disorder

To effectively treat a disease or disorder, doctors must first know the root cause. Such is the case for developmental and epileptic encephalopathies (DEEs), whose root causes can be hugely complex and heterogeneous. Scientists at St. Jude Children's Research Hospital demonstrated the value of DNA methylation patterns for identifying the root cause of DEEs, showing specific gene methylation and genome-wide methylation "episignatures" can help identify the genes that cause DEE. The findings were published today in Nature Communications.

7 Aug 2024

Exploring long COVID: Insights into prevalence, pathophysiology, and treatment

In a new review paper, researchers from the Universities of Arizona, Oxford and Leeds analyzed dozens of previous studies into long COVID to examine the number and range of people affected, the underlying mechanisms of disease, the many symptoms that patients develop, and current and future treatments.

2 Aug 2024

Pioneering study brings leishmaniasis vaccine development closer

Scientists have developed a new, safe and effective way to infect volunteers with the parasite that causes leishmaniasis and measure the body's immune response, bringing a vaccine for the neglected tropical disease a step closer.

2 Aug 2024