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Study reports outbreak of C. vulturna in a hospital in China

Researchers reported an increase in Candida vulturna infections among residents of China between 2019 and 2022.

15 Jun 2023

Breast cancer drug development work moves forward with support from STTR grant

Triple negative breast cancer is an aggressive subtype of breast cancer with worse survival outcomes than most.

14 Jun 2023

Connecting the inflammatory dots: Obesity, depression, and Alzheimer's linked by neuroinflammation

Obesity-induced neuroinflammation significantly contributes to the pathophysiology of depression and Alzheimer's disease. Targeting midlife stage for intervention is crucial to potentially prevent Alzheimer's pathology.

13 Jun 2023

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Researchers evaluated the therapeutic efficacy of Navoximod.

13 Jun 2023

Analyzing the role of LP-284 Hodgkin's lymphoma models and in DNA damage repair

A new research paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, "LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma models and in cells deficient in DNA damage repair."

13 Jun 2023

Antiretroviral treatment efficiently suppresses penile HIV replication

Of the 38 million people worldwide living with HIV, approximately 700,000 are newly infected men, primarily via sexual transmission.

12 Jun 2023

Manipulating white blood cells to eliminate solid tumors

By silencing the molecular pathway that prevents macrophages from attacking our own cells, Penn Engineers have manipulated these white blood cells to eliminate solid tumors.

12 Jun 2023

Study raises new hopes for blood cancer patients with an incomplete response to CAR T cell therapy

The aim of immunotherapy strategies is to use cells in the patient's own immune system to destroy tumor cells. CAR T cell therapy is an immunotherapy that is effective in treating blood cancer.

12 Jun 2023

Study reveals how p62 bodies control redox-independent stress response

Cellular stress, or oxidative stress, occurs when there is a buildup of reactive oxygen species (ROS), which interferes with cellular mechanisms and can even cause damage to proteins, lipids, and DNA.

12 Jun 2023

Mechanistic insights into how the SARS-CoV-2 virus affects the nervous system, alters its function, and causes neuropathology

Study demonstrates that SARS-CoV-2 infection and viral fusogens cause glial and neuronal fusion.

9 Jun 2023

Axol Bioscience collaborates with StrataStem to deliver stem cell based ‘clinical trial in a dish’ for Alzheimer’s disease

Axol Bioscience Ltd. (Axol), a leading pluripotent stem cell technology provider for drug discovery has signed an exclusive agreement with StrataStem to access and commercialize its extensive collection of Alzheimer’s Disease (AD) patient samples.

From Axol Bioscience Ltd 7 Jun 2023

The phenolic composition, antioxidant capacity, and other functional properties of fresh and dried figs

Researchers explored the phytochemical contents and health benefits of consuming figs.

6 Jun 2023

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Researchers describe the Treg-cell-inducing activity of lipid extracts from the feces of specific-pathogen-free mice.

6 Jun 2023

A SARS-CoV-2 spike-targeting bispecific T-cell engager strategy for controlling SARS-CoV-2 infection

Researchers described a novel strategy for controlling severe acute respiratory syndrome coronavirus 2.

5 Jun 2023

Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

Blood-brain barrier breakdown in multiple sclerosis leads to immune cell infiltration into the central nervous system. Antigen presentation at the barrier promotes CD8+ T cell entry, triggering focal breakdown and hindering their invasion.

4 Jun 2023

Researchers characterize a unique molecular mechanism of early stages of programmed cell death

Researchers have for the first time characterized a unique molecular mechanism of the early stages of programmed cell death or apoptosis, a process which plays a crucial role in prevention of cancer.

2 Jun 2023

MatTek and AIM Biotech Partner on Advanced 3D Tissue Culture Organ-on-a-Chip Systems

Today, MatTek Life Sciences and AIM Biotech announced a strategic partnership through which the AIM Biotech portfolio will be available for sale through MatTek.

From MatTek Corporation 2 Jun 2023

Study shows humans may have evolved a spring-like arch to help us walk on two feet

A recent study hypothesized that the arch recoils to propel the COM, which affects the ankle posture.

2 Jun 2023

Study suggests licorice-derived liquiritigenin has breast cancer prevention potential for high-risk postmenopausal women

Researchers evaluated the potential of three licorice (Glycyrrhiza) species, i.e., G. glabra (GG), G. uralensis (GU), and G. infata (GI), and hops (Humulus lupulus), and their main bioactive polyphenols, to prevent breast malignancy.

1 Jun 2023

New insight into how click chemistry EV/peptide/chemokine nanomissiles repair CNS injuries

This new article publication from Acta Pharmaceutica Sinica B, discusses click chemistry extracellular vesicle/peptide/chemokine nanocarriers for treating central nervous system injuries.

31 May 2023

in vivo News and Research

Study reports outbreak of C. vulturna in a hospital in China

Breast cancer drug development work moves forward with support from STTR grant

Connecting the inflammatory dots: Obesity, depression, and Alzheimer's linked by neuroinflammation

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Analyzing the role of LP-284 Hodgkin's lymphoma models and in DNA damage repair

Antiretroviral treatment efficiently suppresses penile HIV replication

Manipulating white blood cells to eliminate solid tumors

Study raises new hopes for blood cancer patients with an incomplete response to CAR T cell therapy

Study reveals how p62 bodies control redox-independent stress response

Mechanistic insights into how the SARS-CoV-2 virus affects the nervous system, alters its function, and causes neuropathology

Axol Bioscience collaborates with StrataStem to deliver stem cell based ‘clinical trial in a dish’ for Alzheimer’s disease

The phenolic composition, antioxidant capacity, and other functional properties of fresh and dried figs

How lipid metabolites in the gut aid in regulatory T-cell differentiation

A SARS-CoV-2 spike-targeting bispecific T-cell engager strategy for controlling SARS-CoV-2 infection

Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

Researchers characterize a unique molecular mechanism of early stages of programmed cell death

MatTek and AIM Biotech Partner on Advanced 3D Tissue Culture Organ-on-a-Chip Systems

Study shows humans may have evolved a spring-like arch to help us walk on two feet

Study suggests licorice-derived liquiritigenin has breast cancer prevention potential for high-risk postmenopausal women

New insight into how click chemistry EV/peptide/chemokine nanomissiles repair CNS injuries

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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