Immune System News and Research

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Stem cell transplantation may offer viable treatment for Alzheimer's disease patients

Alzheimer's disease (AD), affecting millions worldwide, is the leading cause of dementia. The prevalence of AD is rapidly increasing, and will possibly affect over 100 million people by 2050, yet there are no effective therapies for the disease.

31 Oct 2015

UTMB scientists work with InBios International to develop novel diagnostic test for chikungunya

A novel and affordable diagnostic test for chikungunya will soon be available thanks to the work of researchers at the University of Texas Medical Branch at Galveston in partnership with a commercial lab.

30 Oct 2015

Physicians leave severe acne patients on ineffective antibiotics for too long before prescribing more potent drug

A medical records analysis by researchers at NYU Langone Medical Center concludes that physicians who treat severe acne leave too many patients on ineffective antibiotics for far too long before prescribing more potent needed therapy with the medication isotretinoin, sometimes known by its former brand name Accutane.

30 Oct 2015

Specialized type of immunotherapy can boost survival from pancreatic cancer

A new study in mice by researchers at Fred Hutchinson Cancer Research Center has found that a specialized type of immunotherapy — even when used without chemotherapy or radiation — can boost survival from pancreatic cancer, a nearly almost-lethal disease, by more than 75 percent. The findings are so promising, human clinical trials are planned within the next year.

30 Oct 2015

Gut bacteria may increase risk of metabolic syndrome

An excess of bacteria in the gut can change the way the liver processes fat and could lead to the development of metabolic syndrome, according to health researchers.

30 Oct 2015

Basic research for developing toxoplasma vaccine underway

Toxoplasma gondii is a common parasite which causes the development of fatal encephalosis or pneumonia in immunodeficient patients under treatment of AIDS or cancer. Pregnant women who are infected may suffer a miscarriage or the newborn child may suffer from a congenital disease. Currently, a toxoplasma vaccine for humans is not available. Using experimental animals such as mice, basic research for developing an inactivated vaccine is underway.

30 Oct 2015

Scientists one step closer to developing new treatment for inflammatory bowel disease

For patients with inflammatory bowel disease, the possibility of taking a single pill to bring long-lasting relief might seem too good to be true. Scientists at the Lewis Katz School of Medicine at Temple University are on the brink of making that happen, thanks to a recent proof-of-concept study, in which the severity of a form of inflammatory bowel disease in mice was dramatically reduced with one oral dose of a protein isolated from a bacterial biofilm.

30 Oct 2015

SLU VTEU awarded $5.8 million NIH contract to support 'omics' research initiative

Saint Louis University's Vaccine and Treatment Evaluation Unit has received a five-year, $5.8 million contract from the National Institutes of Health to support an "omics" research initiative to study the safety and effectiveness of vaccines and other ways to fight infectious diseases.

30 Oct 2015

Adelaide researchers identify key protein involved in 'super-inflammatory' immune response

Researchers have made another important step in the progress towards being able to block the development of multiple sclerosis (MS) and other autoimmune diseases.

29 Oct 2015

Four Radboud researchers receive ERC grants to form research group

Two researchers from Radboud University and one from Radboudumc are to receive a Starting Grant of 1.5 million Euros from the European Research Council (ERC). This grant is awarded to talented young scientists, giving them the opportunity to form their own research group. Furthermore, astrophysicist Heino Falcke will receive an ERC Proof of Concept Grant.

29 Oct 2015

New studies raise important questions about impact of statin therapy on effectiveness of flu vaccines

A new pair of studies suggests that statins, drugs widely used to reduce cholesterol, may have a detrimental effect on the immune response to influenza vaccine and the vaccine's effectiveness at preventing serious illness in older adults. Published in The Journal of Infectious Diseases, the findings, if confirmed by additional research, may have implications for flu vaccine recommendations, guidelines for statin use around the time of vaccination, and future vaccine clinical trials in seniors.

29 Oct 2015

Rutgers Cancer Institute scientist leads phase III trial of FDA-approved viral melanoma therapy

The U.S. Food and Drug Administration has approved a viral melanoma therapy that was the focus of a phase III clinical trial led by Rutgers Cancer Institute of New Jersey Associate Director for Clinical Science and Chief Surgical Officer Howard L. Kaufman, MD, FACS.

29 Oct 2015

Over 3.7 billion people under 50 have genital HSV-1 infection, shows WHO report

More than 3.7 billion people under the age of 50 – or 67% of the population – are infected with herpes simplex virus type 1 (HSV-1), according to the World Health Organization’s first global estimates of HSV-1 infection published today in the journal PLOS ONE.

29 Oct 2015

IDT’s innovative Alt-R CRISPR-Cas9 System improves genome editing potency, reduces cell toxicity

Integrated DNA Technologies, introduces a new approach to CRISPR—its innovative Alt-R CRISPR-Cas9 System, based on the naturally occurring S. pyogenes CRISPR RNA system.

From Integrated DNA Technologies 29 Oct 2015

UAB researcher awarded NIH grant to study pathogenesis of thrombotic microangiopathy

University of Alabama at Birmingham researcher X. Long Zheng, M.D., Ph.D., has received a five-year, $2.5 million National Institutes of Health grant to study the pathogenesis of thrombotic microangiopathy, or TMA. In simple terms, this means looking for factors that cause or aid the onset of extensive microscopic clots in small blood vessels throughout the body. Though tiny, these spots can damage kidneys, heart and brain, and they can cause death.

29 Oct 2015

New analysis confirms presence of mycotoxins in coffees sold in Spain

An analysis of one hundred coffees sold in Spain has confirmed the presence of mycotoxins -toxic metabolites produced by fungi. In addition, five of the samples that were tested were found to contain ochratoxin A, the only legislated mycotoxin, in amounts that exceeded maximum permitted levels.

29 Oct 2015

Researchers report new way to help improve vaccines using molecules that direct the immune system

As the days get colder and shorter, we carve jack-o-lanterns and drink pumpkin spice lattes. But one fall tradition can actually keep you healthy: getting your flu shot. Like all vaccines, the flu shot trains the immune system to fend off infection, but some need help to produce the full effect.

29 Oct 2015

Oncolytic (cancer-killing) viral therapy approved in the U.S. for use against late-stage melanoma

The U.S. Food and Drug Administration announced on Oct. 27 that it has approved, for the first time, an oncolytic (cancer-killing) viral therapy in the United States. The drug was approved for use against late-stage melanoma, a deadly skin cancer that can be difficult to treat.

29 Oct 2015

Yervoy approved for patients at high risk of developing recurrence of melanoma after surgery

Today the U.S. Food and Drug Administration expanded the approved use of Yervoy (ipilimumab) to include a new use as adjuvant therapy for patients with stage III melanoma, to lower the risk that the melanoma will return following surgery.

29 Oct 2015

Pre-clinical study demonstrates positive effects of advanced prebiotic on neuro-inflammation, anxiety

Clasado Biosciences Limited, the producers and suppliers of the second generation prebiotic Bimuno(R) (B-GOS), a unique trans-galactooligosaccharide, and the Department of Psychiatry, University of Oxford, today announce the results of their latest pre-clinical study demonstrating a major role of the unique carbohydrate complex Bimuno against neuro-inflammation and anxiety.

28 Oct 2015

Immune System News and Research

Stem cell transplantation may offer viable treatment for Alzheimer's disease patients

UTMB scientists work with InBios International to develop novel diagnostic test for chikungunya

Physicians leave severe acne patients on ineffective antibiotics for too long before prescribing more potent drug

Specialized type of immunotherapy can boost survival from pancreatic cancer

Gut bacteria may increase risk of metabolic syndrome

Basic research for developing toxoplasma vaccine underway

Scientists one step closer to developing new treatment for inflammatory bowel disease

SLU VTEU awarded $5.8 million NIH contract to support 'omics' research initiative

Adelaide researchers identify key protein involved in 'super-inflammatory' immune response

Four Radboud researchers receive ERC grants to form research group

New studies raise important questions about impact of statin therapy on effectiveness of flu vaccines

Rutgers Cancer Institute scientist leads phase III trial of FDA-approved viral melanoma therapy

Over 3.7 billion people under 50 have genital HSV-1 infection, shows WHO report

IDT’s innovative Alt-R CRISPR-Cas9 System improves genome editing potency, reduces cell toxicity

UAB researcher awarded NIH grant to study pathogenesis of thrombotic microangiopathy

New analysis confirms presence of mycotoxins in coffees sold in Spain

Researchers report new way to help improve vaccines using molecules that direct the immune system

Oncolytic (cancer-killing) viral therapy approved in the U.S. for use against late-stage melanoma

Yervoy approved for patients at high risk of developing recurrence of melanoma after surgery

Pre-clinical study demonstrates positive effects of advanced prebiotic on neuro-inflammation, anxiety

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