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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

MRI scanners can steer cell-based, tumour busting therapies to exact target sites in the body

Scientists from the University of Sheffield have discovered MRI scanners, normally used to produce images, can steer cell-based, tumour busting therapies to specific target sites in the body.

19 Aug 2015

Benitec prices initial public offering of 1,500,000 American Depositary Shares

Benitec Biopharma Limited, a clinical-stage biotechnology company, is pleased to announce the pricing of its U.S. initial public offering of 1,500,000 American Depositary Shares (ADSs), representing 30,000,000 fully paid ordinary shares of Benitec and warrants to purchase 500,000 ADSs, representing 10,000,000 fully paid ordinary shares, at a price of US$9.21 per ADS and US$0.01 per warrant.

18 Aug 2015

First patient enrolled in Phase II trial of ImmunoPulse IL-12 and pembrolizumab combination therapy

OncoSec Medical Incorporated, a company developing DNA-based intratumoral cancer immunotherapies, today announced enrollment of the first patient into the Phase II Investigator Sponsored Trial led by the University of California, San Francisco to assess the anti-tumor activity, safety, and tolerability of the combination of OncoSec's investigational therapy, ImmunoPulse IL-12, and Merck's approved anti-PD-1 agent, KEYTRUDA (pembrolizumab), in patients with unresectable metastatic melanoma.

18 Aug 2015

New research explores underlying mechanisms by which bacteria acquire antibiotic resistance genes

A scientific peek into bacteria boudoirs is revealing how "sex" among disease-causing microbes can lead different species or strains to become resistant to antibiotic medications.

18 Aug 2015

Newly developed technique delivers wireless power for optogenetics

A miniature device that combines optogenetics - using light to control the activity of the brain - with a newly developed technique for wirelessly powering implanted devices is the first fully internal method of delivering optogenetics.

18 Aug 2015

Studies show jumping genes more active during development of gastrointestinal cancers

Results of a trio of studies done on human cancer tissue biopsies have added to growing evidence that a so-called jumping gene called LINE-1 is active during the development of many gastrointestinal cancers.

18 Aug 2015

DelMar obtains additional funding to support ongoing research project with lead product candidate VAL-083

DelMar Pharmaceuticals, Inc., a biopharmaceutical company focused on developing and commercializing proven cancer therapies in new orphan drug indications, today announced an increase in funding of up to CDN$287,000 from the National Research Council of Canada Industrial Research Assistance Program (NRC-IRAP) to support an ongoing research project.

17 Aug 2015

Improved method for building proteins into antibodies

Some proteins exist so fleetingly in the bloodstream that they can't be given effectively as therapies. However, building them into larger proteins, such as antibodies, can make them persist long enough to be useful. Now a team led by scientists at The Scripps Research Institute (TSRI) has devised an improved method for accomplishing this protein-engineering feat.

14 Aug 2015

TSRI-led team devises selection-based, protein-engineering method to work on obesity therapy

Some proteins exist so fleetingly in the bloodstream that they can’t be given effectively as therapies. However, building them into larger proteins, such as antibodies, can make them persist long enough to be useful. Now a team led by scientists at The Scripps Research Institute has devised an improved method for accomplishing this protein-engineering feat.

14 Aug 2015

New study uses big data analytical methods to reveal 'social character' of genes

A new study at the University of Haifa has used "big data" analytical methods to reveal the "social character" of genes - a phenomenon in certain diseases whereby genes operate jointly rather than independently.

14 Aug 2015

Researchers help explain how malaria infection increases children's risk of developing Burkitt's lymphoma

In equatorial Africa, a region of the globe known as the "lymphoma belt," children are ten times more likely than in other parts of the world to develop Burkitt's lymphoma, a highly aggressive blood cancer that can be fatal if left untreated. That area is also plagued by high rates of malaria, and scientists have spent the last 50 years trying to understand how the two diseases are connected.

14 Aug 2015

New study explains why statins are more beneficial than others in some cases

Statins' success in reducing atherosclerosis-related events has elevated the medications to wonder-drug status, with some researchers advocating for their wider use as a preemptive therapy for cardiovascular disease.

13 Aug 2015

CMC Biologics, PATH Malaria Vaccine Initiative sign agreement for development of specific monoclonal antibodies

CMC Biologics, a global leader in clinical and commercial development and contract manufacture of therapeutic proteins, announced today it has entered into an agreement with the PATH Malaria Vaccine Initiative (MVI) for process development and manufacture of specific monoclonal antibodies to test for their capacity to protect humans from malaria infection.

12 Aug 2015

Ceres receives U.S. patent for iCODE multi-gene trait development system

Ceres, Inc., an agricultural biotechnology company, has been awarded a U.S. patent for its iCODE multi-gene trait development system. The company indicated that the patent award is a key milestone in its plan to further develop and license this technology to other crop companies and organizations.

12 Aug 2015

Researchers develop user-friendly platform for analyzing transcriptomic and epigenomic big data

Researchers at Cincinnati Children's Hospital Medical Center have developed a user-friendly, integrated platform for analyzing the transcriptomic and epigenomic "big data."

12 Aug 2015

New technology advances genome engineering

In his mind, Basil Hubbard can already picture a new world of therapeutic treatments for millions of patients just over the horizon. It's a future in which diseases like muscular dystrophy, cystic fibrosis and many others are treated permanently through the science of genome engineering.

11 Aug 2015

PrediXcan method improves detection of genes linked to complex diseases, biological traits of interest

A new computational method developed by scientists from the University of Chicago improves the detection of genes that are likely to be causal for complex diseases and biological traits. The method, PrediXcan, estimates gene expression levels across the whole genome - a better measure of biological action than single mutations - and integrates it with genome-wide association study (GWAS) data.

11 Aug 2015

Researchers identify first gene that causes common form of mitral valve prolapse

An international research collaboration led by Massachusetts General Hospital investigators has identified the first gene in which mutations cause the common form of mitral valve prolapse (MVP), a heart valve disorder that affects almost 2.5 percent of the population.

11 Aug 2015

Novel treatment target found for RV failure in PAH

Researchers have identified a molecular pathway by which downregulation of microRNA-126 contributes to right ventricular failure in patients with pulmonary arterial hypertension.

10 Aug 2015

Intrexon, Synthetic Biologics form ECC to develop and commercialize novel biotherapeutics for phenylketonuria

Intrexon Corporation, a leader in synthetic biology, and Synthetic Biologics, Inc., a clinical-stage company focused on developing therapeutics to protect the microbiome while targeting pathogen-specific diseases, today announced an Exclusive Channel Collaboration (ECC) to pursue the development and commercialization of novel biotherapeutics for the treatment of patients with phenylketonuria (PKU), a serious and debilitating metabolic disorder.

10 Aug 2015

DNA News and Research

Further Reading

MRI scanners can steer cell-based, tumour busting therapies to exact target sites in the body

Benitec prices initial public offering of 1,500,000 American Depositary Shares

First patient enrolled in Phase II trial of ImmunoPulse IL-12 and pembrolizumab combination therapy

New research explores underlying mechanisms by which bacteria acquire antibiotic resistance genes

Newly developed technique delivers wireless power for optogenetics

Studies show jumping genes more active during development of gastrointestinal cancers

DelMar obtains additional funding to support ongoing research project with lead product candidate VAL-083

Improved method for building proteins into antibodies

TSRI-led team devises selection-based, protein-engineering method to work on obesity therapy

New study uses big data analytical methods to reveal 'social character' of genes

Researchers help explain how malaria infection increases children's risk of developing Burkitt's lymphoma

New study explains why statins are more beneficial than others in some cases

CMC Biologics, PATH Malaria Vaccine Initiative sign agreement for development of specific monoclonal antibodies

Ceres receives U.S. patent for iCODE multi-gene trait development system

Researchers develop user-friendly platform for analyzing transcriptomic and epigenomic big data

New technology advances genome engineering

PrediXcan method improves detection of genes linked to complex diseases, biological traits of interest

Researchers identify first gene that causes common form of mitral valve prolapse

Novel treatment target found for RV failure in PAH

Intrexon, Synthetic Biologics form ECC to develop and commercialize novel biotherapeutics for phenylketonuria

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