Respiratory News and Research

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Basigin/CD147 discarded as an accessory SARS-CoV-2 binding receptor

By using specialized assays customized to detect specific receptor interactions, researchers from the Wellcome Sanger Institute in Cambridge UK find no evidence for direct binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein to a transmembrane glycoprotein known as basigin.

28 Jul 2020

Emergent SARS-CoV-2 D614G spike mutation more infective due to "open" morphology

Researchers from the Los Alamos National Laboratory and Duke Human Vaccine Institute & Department of Surgery demonstrated that globally prevalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with the amino acid substitution D614G in the spike protein is much more infective due to profitable binding encounters with the host receptors.

28 Jul 2020

Identification of MTK1 SAPKKK as new human oxidative stress sensor

In an aging society, various studies are being conducted to explore the relationship between active oxygen and aging-related diseases such as cancer, chronic inflammatory diseases, and metabolic syndrome.

28 Jul 2020

Experimental vaccine rapidly controls coronavirus in the upper and lower airways of nonhuman primates

Two doses of an experimental vaccine to prevent coronavirus disease 2019 (COVID-19) induced robust immune responses and rapidly controlled the coronavirus in the upper and lower airways of rhesus macaques exposed to SARS-CoV-2, report scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. SARS-CoV-2 is the virus that causes COVID-19.

28 Jul 2020

Study sheds wider light on the clinical profile of patients with pulmonary hypertension

When most people think of high blood pressure, they think of being tested with an arm cuff at a doctor's appointment. That type of blood pressure is separate from pulmonary hypertension (PH), which is high blood pressure in the lung arteries.

28 Jul 2020

Evolutionary origins of SARS-CoV-2 identified

By reconstructing the evolutionary history of SARS-CoV-2, the virus that is responsible for the COVID-19 pandemic, an international research team of Chinese, European and U.S. scientists has discovered that the lineage that gave rise to the virus has been circulating in bats for decades and likely includes other viruses with the ability to infect humans.

28 Jul 2020

Pitt collaborative receives $7 million to evaluate convalescent plasma therapy for COVID-19

A team of University of Pittsburgh, Michigan Medicine, Medical University of South Carolina and Stanford Medicine. researchers recently were awarded funds from the National Heart, Lung, and Blood Institute in collaboration with the Biomedical Advanced Research and Development Authority, part of the Office of the Assistant Secretary for Preparedness and Response at the U.S. Department of Health and Human Services, totaling more than $7 million to collaboratively study the role of convalescent plasma in mitigating symptoms of COVID-19 in patients with mild illness and preventing the progression of the disease from mild to severe.

28 Jul 2020

Protein produced by the human immune system can strongly inhibit Sars-Cov-2

A protein produced by the human immune system can strongly inhibit corona viruses, including Sars-Cov-2, the pathogen causing Covid-19. An international team from Germany, Switzerland and the USA successfully showed that the LY6E-Protein prevents coronaviruses from causing an infection.

28 Jul 2020

Medieval remedy can help treat modern day infections

Antibiotic resistance is an increasing battle for scientists to overcome, as more antimicrobials are urgently needed to treat biofilm-associated infections.

28 Jul 2020

Cat catches coronavirus from owners

Cases of pet animals contracting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported since the coronavirus disease (COVID-19) first emerged. Now, a pet cat has become the first animal in Britain to test positive after contracting the virus from its owners.

28 Jul 2020

Moderna coronavirus vaccine candidate moves to phase 3 with 30,000 participants

The world’s most significant coronavirus disease (COVID-19) vaccine study is underway in the United States, with a planned 30,000 volunteers. The phase 3 clinical trial aims to examine the efficacy and safety of the candidate vaccine developed by the National Institutes of Health and Moderna Inc.

28 Jul 2020

A new perspective on lung cancer

Perspectives in Lung Cancer is the first volume of Bentham Books new series, Frontiers in Lung Cancer. The new book, edited by Dr. Keyvan Moghissi et al., is a comprehensive compilation of basic and advanced topics on lung cancer pathology and treatment in a single volume.

28 Jul 2020

Swiss study shows how critical time is in responding to COVID-19

A new study published on the preprint server medRxiv in July 2020 reveals the crucial nature of time as a factor in controlling the mortality rate in the current COVID-19 pandemic.

27 Jul 2020

MU School Of Nursing programs provide assistance to more than 500 nursing homes during COVID-19

As the coronavirus pandemic continues to put a strain on health care systems, nursing homes have become overburdened with the challenge of keeping both patients and staff safe and healthy.

27 Jul 2020

Low plasma vitamin D level appears to be an independent risk factor for COVID-19 infection

Vitamin D is recognized as an important co-factor in several physiological processes linked with bone and calcium metabolism, and also in diverse non-skeletal outcomes, including autoimmune diseases, cardiovascular diseases, type 2 diabetes, obesity and cognitive decline, and infections.

27 Jul 2020

NAU researcher is studying respiratory mechanics in adult survivors of preterm birth

JJ Duke, an assistant professor in Northern Arizona University's Department of Biological Sciences, is studying respiratory mechanics--the "how" of breathing.

27 Jul 2020

Clinical trials of hydroxychloroquine in COVID-19 outpatients reported as safe

According to new research, the use of hydroxychloroquine among outpatients in clinical trials, without high-risk factors for cardiac arrhythmia, is safe.

27 Jul 2020

Study reveals manifold applications of cytokine transcriptional response modules in COVID-19

In a recent bioRxiv* study, UK researchers used interleukin modules to investigate the pathology of coronavirus disease (COVID-19).

27 Jul 2020

Study provides new insights into the host cellular response to SARS-CoV-2 infection

The COVID-19 pandemic caused by the new coronavirus has created an unprecedented public health challenge globally. Little was known about how the infecting cells respond to the virus and how the virus hijacks the host cellular machinery.

27 Jul 2020

Face masks do not lead to false sense of security, shows study

Existing limited evidence suggests that wearing face coverings to protect against COVID-19 does not lead to a false sense of security and is unlikely to increase the risk of infection through wearers foregoing other behaviours such as good hand hygiene, say researchers from the University of Cambridge and King's College London.

27 Jul 2020

Respiratory News and Research

Basigin/CD147 discarded as an accessory SARS-CoV-2 binding receptor

Emergent SARS-CoV-2 D614G spike mutation more infective due to "open" morphology

Identification of MTK1 SAPKKK as new human oxidative stress sensor

Experimental vaccine rapidly controls coronavirus in the upper and lower airways of nonhuman primates

Study sheds wider light on the clinical profile of patients with pulmonary hypertension

Evolutionary origins of SARS-CoV-2 identified

Pitt collaborative receives $7 million to evaluate convalescent plasma therapy for COVID-19

Protein produced by the human immune system can strongly inhibit Sars-Cov-2

Medieval remedy can help treat modern day infections

Cat catches coronavirus from owners

Moderna coronavirus vaccine candidate moves to phase 3 with 30,000 participants

A new perspective on lung cancer

Swiss study shows how critical time is in responding to COVID-19

MU School Of Nursing programs provide assistance to more than 500 nursing homes during COVID-19

Low plasma vitamin D level appears to be an independent risk factor for COVID-19 infection

NAU researcher is studying respiratory mechanics in adult survivors of preterm birth

Clinical trials of hydroxychloroquine in COVID-19 outpatients reported as safe

Study reveals manifold applications of cytokine transcriptional response modules in COVID-19

Study provides new insights into the host cellular response to SARS-CoV-2 infection

Face masks do not lead to false sense of security, shows study

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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