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Ortho announces new appointiments to Board of Directors

Ortho Clinical Diagnostics, a global leader of in vitro diagnostics, today announced that David B. Perez, an accomplished global medical device industry veteran, has been appointed as an independent member to its Board of Directors.

From Ortho-Clinical Diagnostics, Inc. 3 Sep 2020

AAV gene therapy often leads to dorsal root ganglion pathology, show studies

A meta-analysis of non-human primate (NHP) studies showed that adeno-associated virus (AAV) gene therapy often caused dorsal root ganglion (DRG) pathology.

3 Sep 2020

New Gyrolab AAVX Titer Kit launched to support the development cell and gene therapies

Gyros Protein Technologies AB, a pioneer in automated nanoliter-scale immunoassays and a leading provider of peptide synthesizers and reagents, today announced the introduction of Gyrolab® AAVX Titer Kit for adeno-associated virus (AAV) vector titer determination in AAV vector manufacturing.

From Gyros Protein Technologies AB 3 Sep 2020

Antibody responses in recovered COVID-19 individuals from India

India has been hit hard by COVID-19, with at least 66,000 deaths and almost 4 million cases. The need to understand the infection, including the various antibody isotypes, and whether neutralizing antibodies and memory B cells are being produced, has driven much research into the way immunity is developing in Indian patients.

3 Sep 2020

Telerehabilitation works for people recovering from stroke

While virtual medical and rehabilitation appointments seemed novel when COVID-19 first appeared, they now seem to be part of the new norm and might be paving the way to the future.

2 Sep 2020

Trinity College researchers to participate in gene-based clinical trial for motor neuron disease

Researchers at Trinity College Dublin are to participate in an early phase gene-based clinical trial for motor neuron disease (MND). The research team represents one of only four centres in Europe to take part in such an exciting clinical trial for this devastating disease.

2 Sep 2020

Rheumatoid arthritis drugs help improve the early stages of heart disease

Drugs used to treat initial signs of rheumatoid arthritis also improve the early stages of heart disease, according to new research.

2 Sep 2020

Scientists identify key driver in BRAF inhibitor resistant melanoma

Targeted therapy with BRAF-MEK inhibitors is an effective treatment for patients with advanced melanoma that cannot be surgically removed or has spread to other areas of the body.

2 Sep 2020

New method offers hope to patients in critical need of kidney transplant

Kidneys from deceased donors with hepatitis C virus (HCV) infection can be safely transplanted into noninfected recipients when a regimen of direct-acting antiviral therapies is initiated as early as two days after the transplant, according to a study from Massachusetts General Hospital (MGH).

2 Sep 2020

NAMS publishes the 2020 Genitourinary Syndrome Of Menopause Position Statement

The North American Menopause Society announces publication of its 2020 Genitourinary Syndrome of Menopause Position Statement.

1 Sep 2020

Scientists find promising drug candidates for treatment of motor neurone disease

Scientists have taken a significant step forward in the search to find effective new drug candidates for the treatment of motor neurone disease.

1 Sep 2020

Study offers hope for Norwegians suffering from chronic sleep disorders

Approximately 500 000 Norwegians suffer from chronic sleep disorders, also called insomnia. Researchers have long known that cognitive behavioural therapy for insomnia is the best documented treatment, but few people have access to such therapy.

1 Sep 2020

Low dose colchicine significantly reduces risk of cardiovascular death

An Australian-Dutch trial led by Perth GenesisCare cardiologists, Professor Peter Thompson and Dr Mark Nidorf, in collaboration with the Dutch Network for Cardiovascular Research (WCN) in the Netherlands, confirmed that low dose colchicine was safe, well-tolerated over the long-term, and significantly reduced the risk of cardiovascular death, heart attack, and ischemic stroke in patients with chronic coronary disease.

1 Sep 2020

Low dose colchicine significantly reduces risk of cardiovascular death

An Australian-Dutch trial led by Perth GenesisCare cardiologists, Professor Peter Thompson and Dr Mark Nidorf,

1 Sep 2020

Patients with cancer and COVID-19 infection can experience blood clots

UC researchers and physicians are learning that COVID-19 impacts more than just the lungs. The list of potential issues multiplies when doctors also consider its impact on patients with other underlying conditions or the medications used to treat those conditions.

1 Sep 2020

$Sacubitril/valsartan therapy may reduce hospitalization in heart patients with preserved ejection fraction$

Sacubitril/valsartan therapy may reduce hospitalization in heart patients with preserved ejection fraction

Sacubitril/valsartan reduces NT-proBNP, a biomarker predictive of long-term clinical outcomes in heart failure, but does not improve functional capacity compared to individualized background therapy in patients with heart failure with preserved ejection fraction

1 Sep 2020

14 existing drugs identified as SARS-CoV-2 main protease inhibitors

Now, a new study published on the preprint server bioRxiv in August 2020 reports on the identification of 14 compounds that can inhibit the key viral enzyme called the Main Protease (MPro) at micromolar concentrations.

1 Sep 2020

New EU research project seeks to kickstart the development of "Organoid Cell Atlas"

HCA|Organoid is a new EU research project that combines single-cell profiling and organoid technology to validate organoids as faithful models of human biology.

31 Aug 2020

New microgel drug delivery method could improve effectiveness of pancreatic islet transplants

Pancreatic islet transplants, which revive insulin production to treat type 1 diabetes, only last an average of three years.

31 Aug 2020

New dual CAR T cell immunotherapy shows enhanced therapeutic potency to fight HIV

A recent study published in the journal Nature Medicine, led by researchers Todd Allen, PhD, a professor of Medicine at Harvard Medical School and group leader at the Ragon Institute of MGH, MIT and Harvard, and Jim Riley, PhD, a professor of Microbiology in the Perelman School of Medicine at the University of Pennsylvania, describes a new Dual CAR T cell immunotherapy that can help fight HIV infection.

31 Aug 2020