Genetic News and Research

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Mutational targets of SARS-CoV-2 receptor-binding domain for vaccine-antiviral development

The COVID-19 pandemic has spread throughout the whole world within six months, causing millions of infections and hundreds of thousands of deaths. Yet there is no effective vaccine or antiviral to deal with it.

18 Jun 2020

Novel SARS-CoV-2 antibody cocktail impeccably mimics human antibody response

By using both humanized mice and convalescent patients, the researchers from the US and Singapore successfully generated non-competing and highly potent monoclonal antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein that could potentially be combined to form antibody cocktails. Their groundbreaking paper is published in the leading research journal Science.

18 Jun 2020

Discovery of key steps in kidney formation could have implications for treating renal diseases

The discovery of how certain key structures in the kidneys are formed could have important implications for treating renal fibrosis (or scarring), a feature of chronic kidney disease (CKD), according to a new study by a researcher at Massachusetts General Hospital.

18 Jun 2020

Mutations linked to intellectual disability, epileptic seizures affect ion channel's function

Two mutations identified in individuals with developmental and epileptic brain disease can be traced back to the same ion channel.

18 Jun 2020

First genome-wide CRISPR screen reveals genes that control SARS-CoV-2 infection

By performing a genome-wide CRISPR screen on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), U.S. researchers identified novel proviral genes and pathways, and highlighted host genes that may regulate coronavirus disease (COVID-19) pathogenesis, as well as revealing potential targets for novel treatment approaches. Their findings are currently available on the bioRxiv* preprint server.

18 Jun 2020

Research uncovers some of the secrets to longevity

University of Otago researchers have discovered some of the secrets to longevity with new research revealing not smoking and being social engaged throughout older age are common traits of New Zealand centenarians.

18 Jun 2020

Loulou Foundation and IFCR release 'CDKL5 Deficiency Disorder Voice of the Patient Report'

Understanding the patient voice is fundamental for therapy development. Companies need to ensure that what matters most to patients is being assessed, and regulators and payers asks for demonstration of value to support approval and reimbursement.

18 Jun 2020

Scientists use CRISPR tool to make rapid, precise cuts in genomic material

In a series of experiments using human cancer cell lines, scientists at Johns Hopkins Medicine say they have successfully used light as a trigger to make precise cuts in genomic material rapidly, using a molecular scalpel known as CRISPR, and observe how specialized cell proteins repair the exact spot where the gene was cut.

18 Jun 2020

Study reveals new insight into Fuchs’ endothelial corneal dystrophy

The molecular changes that lead to Fuchs' endothelial corneal dystrophy (FECD) occur decades before the disease causes blurry vision and other noticeable symptoms in patients, new research by UT Southwestern scientists shows.

17 Jun 2020

New test will help better manage patients with severe combined immunodeficiency

A new test developed at CHU Sainte-Justine in Montreal will enable better management of patients with severe combined immunodeficiency.

17 Jun 2020

Traffic-related air pollution may affect the developing brain

Researchers at the University of California, Davis, have found a link between traffic-related air pollution and an increased risk for changes in brain development relevant to neurodevelopmental disorders.

17 Jun 2020

USC researchers unlock fatal vulnerability in many cancer cells

Like any cells in the body, cancer cells need sugar - namely glucose - to fuel cell proliferation and growth.

17 Jun 2020

Living environment correlated with reaching centenarian status

When it comes to living to the ripe old age of 100, good genes help but don't tell the full story. Where you live has a significant impact on the likelihood that you will reach centenarian age, suggests a new study conducted by scientists at Washington State University's Elson S. Floyd College of Medicine.

17 Jun 2020

'Microbial dark matter' can affect cholesterol levels in humans

In the darkest parts of the world where light fails to block out the unfathomable bounty of the stars, look up. There are still fewer specks illuminating the universe than there are bacteria in the world, hidden from sight, a whole universe inside just one human gut.

17 Jun 2020

BIA Separations launches novel PrimaS ligand technology to facilitate development of advanced therapies

BIA Separations, a leading bio-chromatography development and manufacturing company, today announced the introduction of its novel PrimaS ligand technology.

17 Jun 2020

Nano-bio hybrid systems could deliver tumor therapy

Announcing a new article publication for BIO Integration journal. In this mini-review article the authors Yuhao Chen, Meng Du, Jinsui Yu, Lang Rao, Xiaoyuan Chen, and Zhiyi Chen from The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China and the National Institute of Biomedical Imaging and Bioengineering, Bethesda, MD, USA consider nanobiohybrids in cancer therapy.

17 Jun 2020

Researchers investigate how neural circuits enable the brain to regulate basal sighing

One group of neurons controls various types of sighing, but they receive their instructions from different areas of the brain depending on the reason for the sigh, according to a study scheduled to publish June 16 in the journal Cell Reports.

17 Jun 2020

Scientists isolate powerful SARS-CoV-2 -neutralizing antibodies from COVID-19 patients

A new study has shown that potent antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could help protect against COVID-19 infection. Preliminary results in animal studies have so far proven successful. The study titled, "Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model," was published in the latest issue of the journal Science.

17 Jun 2020

Cancer results from interaction between individual’s genetics and exposure to carcinogens

A new study led by the University of Hawai?i Cancer Center looks into how and why certain individuals develop cancer and others do not.

16 Jun 2020

Scientists discover unexpected role of heat shock proteins during neuronal differentiation

A research team led by Dr Chaogu Zheng from the School of Biological Sciences at the University of Hong Kong, in collaboration with a team led by Professor Martin Chalfie (2008 Nobel Laureate in Chemistry) from the Department of Biological Sciences at Columbia University, recently discovered an unexpected role of the heat shock proteins, also known as the molecular chaperones, during neuronal differentiation, which refers to the process a neuron takes to acquire its shape and function.

16 Jun 2020

Genetic News and Research

Mutational targets of SARS-CoV-2 receptor-binding domain for vaccine-antiviral development

Novel SARS-CoV-2 antibody cocktail impeccably mimics human antibody response

Discovery of key steps in kidney formation could have implications for treating renal diseases

Mutations linked to intellectual disability, epileptic seizures affect ion channel's function

First genome-wide CRISPR screen reveals genes that control SARS-CoV-2 infection

Research uncovers some of the secrets to longevity

Loulou Foundation and IFCR release 'CDKL5 Deficiency Disorder Voice of the Patient Report'

Scientists use CRISPR tool to make rapid, precise cuts in genomic material

Study reveals new insight into Fuchs’ endothelial corneal dystrophy

New test will help better manage patients with severe combined immunodeficiency

Traffic-related air pollution may affect the developing brain

USC researchers unlock fatal vulnerability in many cancer cells

Living environment correlated with reaching centenarian status

'Microbial dark matter' can affect cholesterol levels in humans

BIA Separations launches novel PrimaS ligand technology to facilitate development of advanced therapies

Nano-bio hybrid systems could deliver tumor therapy

Researchers investigate how neural circuits enable the brain to regulate basal sighing

Scientists isolate powerful SARS-CoV-2 -neutralizing antibodies from COVID-19 patients

Cancer results from interaction between individual’s genetics and exposure to carcinogens

Scientists discover unexpected role of heat shock proteins during neuronal differentiation

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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