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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Clinical trial signals new era in treatment of neurodegererative disorders

The initial clinical trial of a novel approach to treating amyotrophic lateral sclerosis - blocking production of a mutant protein that causes an inherited form of the progressive neurodegererative disease - may be a first step towards a new era in the treatment of such disorders.

4 Apr 2013

TGen to present scientific benefits of whole genome sequencing at myeloma workshop

The scientific benefits of whole genome sequencing at the Translational Genomics Research Institute will be presented at the 14th International Myeloma Workshop, April 3-7 at the Kyoto International Conference Center.

4 Apr 2013

New research shows children with autism have excess of duplicated DNA

Children with autism have increased levels of genetic change in regions of the genome prone to DNA rearrangements, so called "hotspots," according to a research discovery to be published in the print edition of the journal Human Molecular Genetics.

4 Apr 2013

Researchers diagnose genetic disease in embryonic DNA without biopsy

Preimplantation genetic diagnosis (PGD) technologies allow identification of genetic disorders in human preimplantation embryos after in vitro fertilization (IVF) and before the embryo is transferred back to the patient.

3 Apr 2013

Study shows cholesterol rafts can shepherd genetic payloads into cancer cells

DNA, siRNA and miRNA can reprogram cancer cells - that is, if these nucleic acids could cross through the cell membrane. A University of Colorado Cancer Center study published today in the journal Therapeutic Delivery shows that cholesterol "rafts" can shepherd genetic payloads into cancer cells.

3 Apr 2013

Discovery of new signalling pathway creates hope for hormone therapy resistance

A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive breast cancer cells that are resistant to hormone therapies such as tamoxifen, aromatase inhibitors or fulvestrant.

2 Apr 2013

Inovio Pharmaceuticals reports release of phase II clinical trial results of ChronVac-C

Inovio Pharmaceuticals, Inc. today announced the release of preliminary clinical trial results by its collaborator ChronTech AS of their open label phase II clinical study of ChronVac-C, ChronTech's vaccine to treat hepatitis C virus infection.

2 Apr 2013

Ensemble Therapeutics to highlight IL-17A inhibitor Ensemblin at 245th ACS National Meeting

Ensemble Therapeutics today announced that preclinical data showing the advantages of its Ensemblins, novel macrocyclic compounds against challenging drug targets, will be presented at the 245th American Chemical Society National Meeting being held April 7-11, 2013 in New Orleans, LA.

2 Apr 2013

Study links mutated histone protein to rare brain stem cancer in children

Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths.

2 Apr 2013

New research discovery in mosquitoes could lead to possible tools for controlling malaria

A surprising research discovery in mosquitoes could affect future prospects for malaria control. A team of scientists from West Africa, the United States and the United Kingdom found that the mosquito, Anopheles gambiae, which was thought to be splitting into two completely new species, may actually have a more complex range of forms due to frequent inter-mating.

2 Apr 2013

Life Technologies signs distribution agreement with LGC Forensics for ParaDNA system

As the global market leader in human identification, Life Technologies Corporation announced today it signed a global exclusive agreement with LGC Forensics for the right to distribute ParaDNA, a portable rapid DNA system that determines the quality of human DNA faster and more economically than any existing method.

1 Apr 2013

Researchers focus on understanding mechanistic, physiological aspects of conflicts in living cells

Bacteria appear to speed up their evolution by positioning specific genes along the route of expected traffic jams in DNA encoding. Certain genes are in prime collision paths for the moving molecular machineries that read the DNA code, as University of Washington scientists explain in this week's edition of Nature.

30 Mar 2013

Living cells and cell fragments move in response to electric fields, scientists find

Like tiny crawling compass needles, whole living cells and cell fragments orient and move in response to electric fields - but in opposite directions, scientists at the University of California, Davis, have found. Their results, published April 8 in the journal Current Biology, could ultimately lead to new ways to heal wounds and deliver stem cell therapies.

30 Mar 2013

Mount Sinai experts to educate families on identifying signs, symptoms of ASD

The latest report from the US Centers for Disease Control and Prevention estimates that one out of 50 school-aged children has an autism spectrum disorder.

30 Mar 2013

Viral protein hijacks cellular machinery and grabs the wheel

Northwestern Medicine scientists have identified a component of the herpesvirus that "hijacks" machinery inside human cells, allowing the virus to rapidly and successfully invade the nervous system upon initial exposure.

30 Mar 2013

Researchers identify HNF1B gene that can increase risk of ovarian cancer

Researchers at Mayo Clinic Cancer Center have identified a novel gene that can contribute to a woman's susceptibility for developing ovarian cancer. Researchers identified the gene, called HNF1B, through large-scale analysis of more than 16,000 women with ovarian cancer and more than 26,000 healthy women.

28 Mar 2013

New screening procedure determines animal, plant, and microbial substances in foodstuffs

Scientists at the Institute of Molecular Genetics, Genetic Security Research and Consulting at Johannes Gutenberg University Mainz (JGU) have developed a novel screening procedure that provides for highly sensitive, quantifiable analysis of animal, plant, and microbial substances present in foodstuffs.

28 Mar 2013

Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

Inflammation can be thought of as taking two major forms: acute or chronic. Acute inflammation, which can be painful, usually arises quickly and resolves quickly. It accompanies bacterial infections, traumatic injury and is useful to fight infections and promote healing.

28 Mar 2013

Chromatrap chromatin immunoprecipitation (ChIP) assay range added to Porvair Sciences’ portfolio of products for epigenetics

Porvair Sciences has announced the addition of the novel Chromatrap chromatin immunoprecipitation (ChIP) assay range to its portfolio of products for epigenetics.

From Chromatrap® - Porvair Sciences Ltd 28 Mar 2013

Researchers uncover DNA rearrangement process for sex determination in Tetrahymena

It's been more than 50 years since scientists discovered that the single-celled organism Tetrahymena thermophila has seven sexes. But in all that time, they've never known how each cell's sex, or "mating type," is determined.

28 Mar 2013

DNA News and Research

Further Reading

Clinical trial signals new era in treatment of neurodegererative disorders

TGen to present scientific benefits of whole genome sequencing at myeloma workshop

New research shows children with autism have excess of duplicated DNA

Researchers diagnose genetic disease in embryonic DNA without biopsy

Study shows cholesterol rafts can shepherd genetic payloads into cancer cells

Discovery of new signalling pathway creates hope for hormone therapy resistance

Inovio Pharmaceuticals reports release of phase II clinical trial results of ChronVac-C

Ensemble Therapeutics to highlight IL-17A inhibitor Ensemblin at 245th ACS National Meeting

Study links mutated histone protein to rare brain stem cancer in children

New research discovery in mosquitoes could lead to possible tools for controlling malaria

Life Technologies signs distribution agreement with LGC Forensics for ParaDNA system

Researchers focus on understanding mechanistic, physiological aspects of conflicts in living cells

Living cells and cell fragments move in response to electric fields, scientists find

Mount Sinai experts to educate families on identifying signs, symptoms of ASD

Viral protein hijacks cellular machinery and grabs the wheel

Researchers identify HNF1B gene that can increase risk of ovarian cancer

New screening procedure determines animal, plant, and microbial substances in foodstuffs

Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

Chromatrap chromatin immunoprecipitation (ChIP) assay range added to Porvair Sciences’ portfolio of products for epigenetics

Researchers uncover DNA rearrangement process for sex determination in Tetrahymena

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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