Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Research reveals rising rates of liver cancer

New research reveals rising rates of liver cancer around the world, despite advances aimed at preventing the disease. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

23 Mar 2020

MAFLD: New terminology can help improve treatment for patients with fatty liver disease

An international consensus panel led by researchers from The Westmead Institute for Medical Researchhas highlighted the need to redefine Non-Alcoholic Fatty Liver Disease, and to name it Metabolic Associated Fatty Liver Disease. Researchers highlighted that the new terminology will better reflect its causes, and improve public health initiatives.

18 Mar 2020

Obese children more prone to anxiety, depression and shortening of life

Two studies published in the journals PLOS Medicine and BMC Medicine in March 2020 show that obesity in childhood is linked to a higher risk of future anxiety, depression, and death in early adult life compared to children in the general population. This could shape efforts to detect specific risk factors that predispose children to obesity and thus prevent it.

18 Mar 2020

Low-dose aspirin linked to lower risk of hepatocellular carcinoma and liver-related mortality

Among adults at high risk of liver cancer, those who took low-dose aspirin were less likely to develop the disease or to die from liver-related causes.

12 Mar 2020

Immunosuppressive therapy does not increase risk of vulvar or vaginal cancer in women with IBD

In a new retrospective study, researchers found that the use of immunosuppressive therapy does not increase the occurrence or recurrence of vulvar or vaginal cancer in women with inflammatory bowel disease (IBD).

11 Mar 2020

How effective is Gabapentin in alcohol use disorder?

A new study published in the journal JAMA Internal Medicine in March 2020 reports the striking efficacy of the drug gabapentin in helping people with alcohol use disorder (AUD) with their alcohol withdrawal symptoms.

9 Mar 2020

Liver fibrosis associated with one type of heart failure, regardless of HIV or hepatitis C status

While there is an association between liver fibrosis and heart failure, the mechanisms for this association are currently unclear but may be of particular importance for people living with human immunodeficiency virus (HIV) and/or hepatitis C, both of which are chronic infections that affect the liver and heart.

7 Mar 2020

Type 2 diabetes mellitus responds to weight loss surgery

Type 2 diabetes mellitus (T2DM) is a metabolic condition with close links to weight gain. Since weight loss is a proven way to control T2DM, it is to be expected that surgeries to achieve weight loss should result in better regulation of blood glucose levels.

4 Mar 2020

Yale discovery has implications for treatment of diabetes and non-alcoholic fatty liver disease

Many health problems in the developed world stem from the disruption of a delicate metabolic balance between glucose production and energy utilization in the liver.

4 Mar 2020

Researchers detect a novel cause of acquired lipodystrophy

Nonalcoholic fatty liver disease (NAFLD) is mostly diagnosed in overweight and obese people. However, severe forms of NAFLD can also be detected in rare genetic diseases such as lipodystrophy or in patients with HIV, putting them at a high risk for developing liver failure, diabetes and cardiovascular diseases.

3 Mar 2020

Major investment can help improve technology aimed at turning bad fat to good fat

A significant investment from a Purdue University alumnus and his wife will help further develop technology aimed at treating obesity and diabetes by turning bad fat into good fat inside the body.

28 Feb 2020

Prolonged exposure to a pair of antioxidant proteins may fuel liver enlargement

All life is challenged by oxidants -- reactive molecules or compounds that remove electrons from other molecules -- often with adverse effect, commonly referred to as oxidative stress.

25 Feb 2020

UCLA study finds new way for tracking treatment of rare liver disease in children

UCLA researchers who previously found that intravenous administration of fish oil can treat a rare but potentially deadly form of liver disease in children have now monitored levels of a small molecule at the center of the disorder to track treatment results.

19 Feb 2020

Vitamin E can safely treat fatty liver disease in patients with HIV

A type of fatty liver disease that commonly affects patients with HIV can be safely treated with vitamin E, a McGill-led study has found.

16 Feb 2020

New set of recommendations for managing liver failure in the ICU

For critical care specialists, hepatic failure poses complex challenges unlike those of other critical illnesses.

16 Feb 2020

Combination of green tea extract and exercise mitigates fatty liver disease in mice

The combination of green tea extract and exercise reduced the severity of obesity-related fatty liver disease by 75% in mice fed a high-fat diet, according to Penn State researchers, whose recent study may point to a potential health strategy for people.

16 Feb 2020

Study shows link between fast food intake and weight gain in preschoolers

There is a strong link between the amount of fast food that pre-school age children consume and their likelihood of becoming overweight or obese, according to a new Dartmouth-led study, published in the journal Pediatric Obesity.

14 Feb 2020

Study finds inadequate testing for Tennessee infants exposed to hepatitis C

Most Tennessee infants exposed to hepatitis C at birth are not later tested to see if they acquired the virus, according to a study by researchers at Monroe Carell Jr. Children's Hospital at Vanderbilt and the Vanderbilt Center for Child Health Policy.

14 Feb 2020

BU study highlights the need for more state-level alcohol control laws

A new Boston University School of Public Health (BUSPH) study finds a substantial increase in the number and strength of state laws to reduce impaired driving over the last 20 years, while laws to reduce excessive drinking remained unchanged.

14 Feb 2020

Minigenes produced by CRISPR combat liver disease in mice

A new gene-editing technique based on CRISPR was used to successfully avoid the development of a liver disease that can be caused by hundreds of mutations, as well as to ease the symptoms in mice. This proof-of-concept study was published online in the journal Science Advances in February 2020.

12 Feb 2020

Liver Disease News and Research

Further Reading

Research reveals rising rates of liver cancer

MAFLD: New terminology can help improve treatment for patients with fatty liver disease

Obese children more prone to anxiety, depression and shortening of life

Low-dose aspirin linked to lower risk of hepatocellular carcinoma and liver-related mortality

Immunosuppressive therapy does not increase risk of vulvar or vaginal cancer in women with IBD

How effective is Gabapentin in alcohol use disorder?

Liver fibrosis associated with one type of heart failure, regardless of HIV or hepatitis C status

Type 2 diabetes mellitus responds to weight loss surgery

Yale discovery has implications for treatment of diabetes and non-alcoholic fatty liver disease

Researchers detect a novel cause of acquired lipodystrophy

Major investment can help improve technology aimed at turning bad fat to good fat

Prolonged exposure to a pair of antioxidant proteins may fuel liver enlargement

UCLA study finds new way for tracking treatment of rare liver disease in children

Vitamin E can safely treat fatty liver disease in patients with HIV

New set of recommendations for managing liver failure in the ICU

Combination of green tea extract and exercise mitigates fatty liver disease in mice

Study shows link between fast food intake and weight gain in preschoolers

Study finds inadequate testing for Tennessee infants exposed to hepatitis C

BU study highlights the need for more state-level alcohol control laws

Minigenes produced by CRISPR combat liver disease in mice

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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