Respiratory News and Research

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NUS teams develop three nasopharyngeal swab designs for COVID-19 testing

Since the outbreak of COVID-19, there has been a global surge in demand for nasopharyngeal (NP) swabs, a key element in testing for SARS-CoV-2. Singapore is no exception. Commercially available NP swabs used in COVID-19 test kits are often out of stock due to supply chain disruptions.

13 Jul 2020

Delirium linked to long-term cognitive decline

A new meta-analysis of 24 observational studies from researchers at Columbia University Vagelos College of Physicians and Surgeons found that delirium may cause significant long-term cognitive decline.

13 Jul 2020

States allow in-person nursing home visits as families charge residents die ‘of broken hearts’

States across the country are beginning to roll back heart-wrenching policies instituted when the coronavirus pandemic began and allow in-person visits at nursing homes and assisted living centers, offering relief to frustrated families.

13 Jul 2020

Study shows smoking is associated with a higher likelihood of COVID-19 progression

As the number of young adults infected with the coronavirus surges throughout the nation, a new study by researchers at UCSF Benioff Children's Hospitals indicates that youth may not shield people from serious disease.

13 Jul 2020

Adding to COVID stress, families of health workers fight for denied workers’ comp benefits

James “Mike” Anderson was a hospital employee in suburban Philadelphia with a low-profile though critical job: changing air filters in COVIAdding To COVID Stress, Families Of Health Workers Fight For Denied Workers’ Comp BenefitsCOVID cases in Bucks County, Pennsylvania, had ramped up to as many as 90 per day.

13 Jul 2020

South Carolina reports first cases of coronavirus-related pediatric inflammatory syndrome

Coronavirus-related pediatric inflammatory syndrome, also known as multisystem inflammatory syndrome in children, or MIS-C, is a rare inflammatory condition that affects children and adolescents and is tied to exposure to the novel coronavirus.

13 Jul 2020

Researchers develop COVID-19 mortality risk calculator

A new study published in July 2020 on the preprint server medRxiv describes the use of machine learning to provide a better understanding of the risk factors in large and mixed groups. The use of algorithms can help objectively evaluate these factors and perhaps capture interactions that could be missed in a purely observational study.

13 Jul 2020

Dysfunctional T cells present at high levels in severe COVID-19

Now, a new study by researchers at Saarland University, Germany, and published on the preprint server medRxiv in July 2020 shows that there are higher levels of anti-SARS-CoV-2 T cells, which show significant alterations in the phenotype and function.

12 Jul 2020

No unique viral sequences found in pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2

In contrast to previous hypotheses, researchers from the University College London and Great Ormond Street Hospital for Children NHS Foundation Trust found no evidence of unique viral sequences from patients with pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS). Their study is published on the medRxiv* preprint server.

12 Jul 2020

Digestive manifestations common but mild among hospitalized COVID-19 patients

A team of 121 researchers from the United States and Canada reports that while digestive manifestations seem to be common among people hospitalized with coronavirus disease 2019 (COVID-19), the majority appear to be mild and not associated with severe clinical outcomes.

12 Jul 2020

Increasing level of SARS-CoV-2 detected in Montpellier wastewater

Researchers at The French National Centre for Scientific Research have identified a recent increase in the amount of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA at the main wastewater treatment plant (WWTP) of the Montpellier metropolitan area.

12 Jul 2020

Global government COVID-19 interventions - no one-fits-all solution exists

A new study published on the preprint server medRxiv in July 2020 shows that some less intrusive NPIs are better than total lockdown. This may help to shape future measures should repeated waves of the pandemic occur.

12 Jul 2020

First extensive review of COVID-19's effects on all affected organs outside the lungs

After only a few days caring for critically ill COVID-19 patients at the start of the outbreak in New York City, Aakriti Gupta, MD, realized that this was much more than a respiratory disease.

12 Jul 2020

Study documents intrauterine transmission of SARS-CoV-2 infection during pregnancy

A baby girl in Texas - born prematurely to a mother with COVID-19 - is the strongest evidence to date that intrauterine (in the womb) transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can occur, reports The Pediatric Infectious Disease Journal, the official journal of The European Society for Paediatric Infectious Diseases.

12 Jul 2020

COVID-19-associated stroke patients have higher risk for severe disability and death

Acute ischemic strokes (AIS) associated with COVID-19 are more severe, lead to worse functional outcomes and are associated with higher mortality , according to new research published yesterday in Stroke, a journal of the American Stroke Association, a division of the American Heart Association.

12 Jul 2020

Fat cell hormone enhances therapeutic potential of MSC therapy

Mesenchymal stem cells (MSCs) have the potential to differentiate into a range of different cell types, including bone, fat, and muscle cells.

12 Jul 2020

MUSC chosen to build prototype for increasing ICU surge capacity during COVID-19

To prepare for current and future waves of COVID-19, the U.S. Army's Telemedicine and Advanced Technology Research Center asked teams from across the country to compete to build a telehealth prototype that would provide adequate ICU capacity when cases surge.

12 Jul 2020

History of rape associated with 'dysfunctional breathing'

Rape and sexual trauma may have long-lasting consequences for physical health as well as mental health, University of Otago researchers have found.

11 Jul 2020

ONR Global awards research grant to produce low-cost ventilators for use by hospitals in São Paulo

Brazil has been one of the most affected countries in the world by COVID-19. A group of researchers led by Prof. Marcelo Zuffo and Prof. Raul Lima from the Escola Politécnica da Universidade de São Paulo received US $ 199,943 for one year from the Office of Naval Research (ONR) Global. The project is co-funded by ONR’s Warfighter Performance Department.

10 Jul 2020

New clinical trial to assess safety and efficacy of convalescent plasma to prevent COVID-19

There is only one approved, specific treatment for COVID-19, the illness caused by the novel coronavirus SARS-CoV-2, albeit with modest efficacy.

10 Jul 2020

Respiratory News and Research

NUS teams develop three nasopharyngeal swab designs for COVID-19 testing

Delirium linked to long-term cognitive decline

States allow in-person nursing home visits as families charge residents die ‘of broken hearts’

Study shows smoking is associated with a higher likelihood of COVID-19 progression

Adding to COVID stress, families of health workers fight for denied workers’ comp benefits

South Carolina reports first cases of coronavirus-related pediatric inflammatory syndrome

Researchers develop COVID-19 mortality risk calculator

Dysfunctional T cells present at high levels in severe COVID-19

No unique viral sequences found in pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2

Digestive manifestations common but mild among hospitalized COVID-19 patients

Increasing level of SARS-CoV-2 detected in Montpellier wastewater

Global government COVID-19 interventions - no one-fits-all solution exists

First extensive review of COVID-19's effects on all affected organs outside the lungs

Study documents intrauterine transmission of SARS-CoV-2 infection during pregnancy

COVID-19-associated stroke patients have higher risk for severe disability and death

Fat cell hormone enhances therapeutic potential of MSC therapy

MUSC chosen to build prototype for increasing ICU surge capacity during COVID-19

History of rape associated with 'dysfunctional breathing'

ONR Global awards research grant to produce low-cost ventilators for use by hospitals in São Paulo

New clinical trial to assess safety and efficacy of convalescent plasma to prevent COVID-19

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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