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Combination therapy shows promising results in patients with recurrent ER-positive endometrial cancer

A combination therapy that targets cancer cells from within and without caused tumors to shrink or stabilize in 75% of patients with recurrent or persistent estrogen receptor- (ER-) positive endometrial cancer, results from a recent clinical trial show.

19 Mar 2022

A single gene can control brain cell growth in humans, research shows

Controlling how cells grow is fundamental to ensuring proper brain development and stopping aggressive brain tumors.

19 Mar 2022

Reactivating Piezo1 protein could help repair broken down, dystrophic muscles

One protein, Piezo1, is key to marshalling muscle stem cells' unique shapes and response to injuries, but it is in low supply in those with Duchenne muscular dystrophy, according to a team at the Perelman School of Medicine at the University of Pennsylvania.

18 Mar 2022

Understanding how coronavirus, RS virus and rhinovirus affect children

When Inger Heimdal started studying the coronavirus in children in 2014, not many people thought the topic sounded particularly exciting.

18 Mar 2022

Study: Targeting astrocytes reduces tau-related brain damage and inflammation in mice

Alzheimer's disease is the most common and best known of the tauopathies, a set of neurodegenerative brain diseases caused by toxic tangles of the protein tau.

18 Mar 2022

Scientists generate an atlas of human and mouse white adipocytes

Once considered to be inert, white adipose tissue is now recognized to be dynamic and to play an interactive role in a wide array of biological and metabolic processes.

18 Mar 2022

Deactivation of specific brain cells makes mice more resilient against chronic stress

It is well known that long-term exposure to stress can lead to serious psychiatric problems. However, the precise mechanisms underpinning the stress response have remained largely elusive.

18 Mar 2022

Texas Biomed and UAB partnership uncovers a new, potent antibody cocktail against all coronaviruses

As SARS-CoV-2 has continued to evolve and outsmart existing treatments, scientists have not let up looking for ever-more effective tools to keep people safe and successfully recover from COVID-19, and to prepare for future outbreaks.

18 Mar 2022

Neutrophils found to initiate COVID-19-associated olfactory epithelial damage in hamsters

Researchers evaluated the underlying cellular mechanisms of SARS-CoV-2-induced olfactory epithelium damage in golden Syrian hamsters.

18 Mar 2022

A complete transcriptomic analysis of astrocytes in Alzheimer's disease

An international group of researchers led by the UAB analyzed the genes that are expressed in neurons and astrocytes based on data from 800 individuals and compared what happens in Alzheimer's patients and in people without diagnosed dementia.

18 Mar 2022

Digital media can promote safer behavior in authoritarian communities during the pandemic, experts say

Ultra-Orthodox communities in Israel have been more affected by the COVID-19 pandemic than other segments of the Israeli population.

18 Mar 2022

New virus-based approach for measuring variations in gene regulatory elements

Tohoku University scientists in Japan have developed a virus-based approach for measuring variations in gene regulatory elements, called transcription factors, as conditions change in live organisms.

18 Mar 2022

Scientists develop virus-blocking textile that effectively repulses SARS-CoV-2

Scientists have described a virus-blocking textile that prevents transmission of SARS-CoV-2 via repulsive Coulomb force and human body triboelectric energy harvesting.

18 Mar 2022

Innate and adaptive immune responses to BNT162b2 vaccination in mice

Researchers analyzed the innate and adaptive responses to the mRNA-based BNT162b2 COVID-19 vaccine in mice.

18 Mar 2022

Characteristics of super-spreaders of novel coronaviruses

Researchers conducted a systematic review to evaluate the characteristics of super-spreaders of three novel coronaviruses that caused SARS, MERS, and COVID-19.

18 Mar 2022

Study shows BCG vaccination reduces SARS-CoV-2-induced lung inflammation in hamsters

Researchers tested the effectiveness of the BCG vaccine in SARS-CoV-2-infected Syrian hamsters.

18 Mar 2022

Researchers argue that Omicron's lower severity is a coincidence

Researchers raised concern regarding the emergence of new SARS-CoV-2 variants with unpredictable severity and immune evasion potential due to its ongoing fast-paced antigenic evolution.

18 Mar 2022

New discovery points to potential drug targets for ASXL1-mutant chronic myelomonocytic leukemia

New research from Mayo Clinic's Center for Individualized Medicine finds that patients with ASXL1-mutant chronic myelomonocytic leukemia - an uncommon type of cancer of the bone marrow - have distinctive epigenetic changes that can activate harmful genes and cause the cancer to grow faster.

18 Mar 2022

New approach radically increases the success of breast cancer immunotherapy

A study published in the journal Nature Cancer, carried out within the Cancer Programme at the Hospital del Mar Medical Research Institute (IMIM-Hospital del Mar) by the Cancer Stem Cells and Metastasis Dynamics Laboratory, led by Dr. Toni Celià-Terrassa, and the Laboratory of Molecular Cancer Therapy, coordinated by Dr. Joan Albanell, with the participation of international centers, has discovered an approach that radically increases the success of immunotherapy in one of the most aggressive types of tumors, triple-negative breast cancer.

17 Mar 2022

Why does the SARS-CoV-2 Omicron variant escape immunity?

Researchers reveal the underlying mechanism associated with the Omicron variant’s increased transmissibility and ability to evade immunity.

17 Mar 2022

B Cell News and Research

Combination therapy shows promising results in patients with recurrent ER-positive endometrial cancer

A single gene can control brain cell growth in humans, research shows

Reactivating Piezo1 protein could help repair broken down, dystrophic muscles

Understanding how coronavirus, RS virus and rhinovirus affect children

Study: Targeting astrocytes reduces tau-related brain damage and inflammation in mice

Scientists generate an atlas of human and mouse white adipocytes

Deactivation of specific brain cells makes mice more resilient against chronic stress

Texas Biomed and UAB partnership uncovers a new, potent antibody cocktail against all coronaviruses

Neutrophils found to initiate COVID-19-associated olfactory epithelial damage in hamsters

A complete transcriptomic analysis of astrocytes in Alzheimer's disease

Digital media can promote safer behavior in authoritarian communities during the pandemic, experts say

New virus-based approach for measuring variations in gene regulatory elements

Scientists develop virus-blocking textile that effectively repulses SARS-CoV-2

Innate and adaptive immune responses to BNT162b2 vaccination in mice

Characteristics of super-spreaders of novel coronaviruses

Study shows BCG vaccination reduces SARS-CoV-2-induced lung inflammation in hamsters

Researchers argue that Omicron's lower severity is a coincidence

New discovery points to potential drug targets for ASXL1-mutant chronic myelomonocytic leukemia

New approach radically increases the success of breast cancer immunotherapy

Why does the SARS-CoV-2 Omicron variant escape immunity?

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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