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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

SQUIRE phase III study shows necitumumab improves median overall survival in squamous NSCLC patients

This week, Lancet Oncology reports results of a 1,093-person phase III clinical trial of the drug necitumumab (IMC-11F8) combined with chemotherapies gemcitabine and cisplatin against stage IV squamous non-small cell lung cancer. With addition of necitumumab, median overall survival was 11.5 months compared with median survival of 9.9 months with the two chemotherapies alone.

11 Jun 2015

New approach to classifying brain tumors could lead to significant improvements in diagnosis, treatment

A Case Comprehensive Cancer Center brain surgeon and neurosurgery professor is among the primary authors of a new approach to classifying tumors that could lead to significant improvements in their diagnosis and treatment. The research and recommendations appear online June 10 in The New England Journal of Medicine.

11 Jun 2015

Findings point to new therapy against prostate and other cancers

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have found that a drug candidate with anticancer potential can be activated by one of the body's natural responses to cellular stress. Once activated, the agent can kill prostate cancer cells.

11 Jun 2015

New study links sleep deprivation to etiology of biological aging in older adults

A new study suggests that one night of partial sleep deprivation promotes biological aging in older adults. Results show that one night of partial sleep deprivation activates gene expression patterns in peripheral blood mononuclear cells (PBMCs) consistent with increasing accumulation of damage that initiates cell cycle arrest and increases susceptibility to senescence.

11 Jun 2015

Creative Diagnostics announces launch of antibody generation service based on DNA immunization technology

Creative Diagnostics, the global diagnostics service and product supplier, is pleased to announce its launch of custom antibody production service based on DNA immunization technology. This DNA immunization technology allows high success rate in generation of high-affinity antibodies recognizing difficult-to-express proteins in their native confirmation, such as GPCRs, ion channels and other multiple membrane spanning proteins.

10 Jun 2015

EU research project to study how social inequalities influence healthy ageing

The Lifepath project, involving 15 institutions in Europe, the US and Australia, has been supported by a six million euro grant from the EU's Horizon 2020 programme...

10 Jun 2015

Study on how maternal proteins help regulate initial cell divisions during early development

Researchers in the University of Georgia's Regenerative Bioscience Center are visually capturing the first process of chromosome alignment and separation at the beginning of mouse development. The findings could lead to answers to questions concerning the mechanisms leading to birth defects and chromosome instability in cancer cells.

10 Jun 2015

MIPT researchers develop ultrasensitive nanomechanical sensor to identify tumor markers

Two young researchers working at the MIPT Laboratory of Nanooptics and Plasmonics, Dmitry Fedyanin and Yury Stebunov, have developed an ultracompact highly sensitive nanomechanical sensor for analyzing the chemical composition of substances and detecting biological objects, such as viral disease markers, which appear when the immune system responds to incurable or hard-to-cure diseases, including HIV, hepatitis, herpes, and many others.

10 Jun 2015

Manchester first to implement Congenica's Sapientia technology to provide fast, accurate diagnosis for genetic diseases

10,000 new patients a year are treated by the Manchester Centre for Genomic Medicine (MCGM) for a range of rare diseases including cancers, developmental disorders and disabilities including hearing and vision loss - diagnosis can be time-consuming and invasive.

10 Jun 2015

Massey researchers aim to develop models that can predict complications from stem cell transplantation

Researchers at VCU Massey Cancer Center's Bone Marrow Transplant Program have recently published findings from a phase 2 clinical trial that demonstrate lymphocyte recovery in related and unrelated stem cell transplant recipients generally falls into three patterns that are significantly associated with survival.

10 Jun 2015

OncoSec Medical reports net loss of $14.7 million for FY 2015

OncoSec Medical Inc., a company developing DNA-based intratumoral cancer immunotherapies, today announced financial results for the nine months ended April 30, 2015.

9 Jun 2015

Whole genome sequencing can help implement rapid-response infection control protocols

Whole genome sequencing can quickly isolate the specific strain of bacteria causing an outbreak, identify the source of contamination, and enable rapid infection prevention to stop the spread of infection, according to a study published today.

9 Jun 2015

Cell fusion triggers multiple genetic changes that convert normal cells to cancer cells

Although there is no one established universal cause of cancer, genetic changes are central to its development. The accumulation of spontaneous genetic changes, or mutations, that occur when cells divide can be hastened by exposure to carcinogens such as cigarette smoke (lung cancer) and infectious agents such as the papillomavirus (cervical cancer).

9 Jun 2015

Researchers receive $10 million grant for citrus greening research project

To help develop a therapeutic treatment for citrus greening disease, a bacterial infection that threatens the future of the U.S. citrus industry, the United States Department of Agriculture Specialty Crop Research Initiative has awarded a diverse group of researchers a $10 million grant.

9 Jun 2015

Clinical data of Trovagene's Precision Cancer Monitoring platform to be presented at two medical conferences

Trovagene, Inc., a developer of cell-free molecular diagnostics, announced today that clinical data featuring its Precision Cancer MonitoringSM platform will be presented at the 2015 Cancer Markers and Liquid Biopsies conference in San Diego, CA on June 11-12, and at the AACR Precision Medicine Series: Integrating Clinical Genomics and Cancer Therapy in Salt Lake City, UT on June 13-16.

8 Jun 2015

Merck KGaA, Darmstadt, Germany forms Global Fertility Alliance with Illumina and Genea

Merck KGaA, Darmstadt, Germany, a leading company for innovative and top-quality high-tech products in healthcare, life science and performance materials today announced the formation of the Global Fertility Alliance, a new collaboration to advance excellence in fertility technologies and processes within the assisted reproductive treatment (ART) laboratory.

From Illumina, Inc. 8 Jun 2015

Study: Non-invasive prenatal testing works in women at high risk of having babies with Down's syndrome

Results from a national study of non-invasive prenatal testing (NIPT) in women at high risk of having a baby with Down's syndrome will be presented at the annual conference of the European Society of Human Genetics today (Saturday).

8 Jun 2015

Researchers discover genetic mutation responsible for thoracic aortic aneurysm and dissection

Thoracic aortic aneurysm and dissection (TAAD), an enlargement or tearing of the walls of the aorta in the chest, is, together with abdominal aortic aneurysms, responsible for about 2% of all deaths in Western countries. The aorta is the largest artery in the body, and carries blood from the heart. About one out of every five patients with TAAD has a family member with the same disorder, therefore indicating a genetic cause.

8 Jun 2015

New UAB research identifies link between temporal lobe epilepsy and memory loss

New research from the University of Alabama at Birmingham identifies an epigenetic cause for why patients with temporal lobe epilepsy tend to have memory loss, and suggests a potential way to reverse that loss.

8 Jun 2015

Study suggests new strategies to stop spread of Staph infections

Staphylococcus aureus -- better known as Staph -- is a common inhabitant of the human nose, and people who carry it are at increased risk for dangerous Staph infections.

7 Jun 2015

DNA News and Research

Further Reading

SQUIRE phase III study shows necitumumab improves median overall survival in squamous NSCLC patients

New approach to classifying brain tumors could lead to significant improvements in diagnosis, treatment

Findings point to new therapy against prostate and other cancers

New study links sleep deprivation to etiology of biological aging in older adults

Creative Diagnostics announces launch of antibody generation service based on DNA immunization technology

EU research project to study how social inequalities influence healthy ageing

Study on how maternal proteins help regulate initial cell divisions during early development

MIPT researchers develop ultrasensitive nanomechanical sensor to identify tumor markers

Manchester first to implement Congenica's Sapientia technology to provide fast, accurate diagnosis for genetic diseases

Massey researchers aim to develop models that can predict complications from stem cell transplantation

OncoSec Medical reports net loss of $14.7 million for FY 2015

Whole genome sequencing can help implement rapid-response infection control protocols

Cell fusion triggers multiple genetic changes that convert normal cells to cancer cells

Researchers receive $10 million grant for citrus greening research project

Clinical data of Trovagene's Precision Cancer Monitoring platform to be presented at two medical conferences

Merck KGaA, Darmstadt, Germany forms Global Fertility Alliance with Illumina and Genea

Study: Non-invasive prenatal testing works in women at high risk of having babies with Down's syndrome

Researchers discover genetic mutation responsible for thoracic aortic aneurysm and dissection

New UAB research identifies link between temporal lobe epilepsy and memory loss

Study suggests new strategies to stop spread of Staph infections

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