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Blocking LSD1 restores immune response in early oral cancer

Oral squamous cell carcinoma (OSCC) is a leading cause of cancer-related deaths, and early detection is key to improving patient outcomes. However, the mechanisms driving the transition from preneoplastic lesions to full-blown cancer are not well understood.

11 May 2025

Early menopause increases risk of fatty liver disease and metabolic disorders

Women who experience menopause before the age of 50 - and especially before the age of 45 - are more likely to develop fatty liver disease and its related metabolic risk factors within one year after menopause, according to research presented at the first Joint Congress between the European Society of Paediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE).

11 May 2025

Virtual nurse shows promise in promoting vaccinations

Can a virtual nurse persuade people to get vaccinated? Scientists from SWPS University have proven that it is possible. Finding new forms of informing people about vaccinations is particularly important for public health while some question their validity.

10 May 2025

New QR4 model identifies hidden risk factors in cardiovascular disease

Collaborative research, led from the University of Oxford and published today in Nature Medicine, has developed a new tool called QR4 that more accurately predicts an individual's 10-year risk of cardiovascular diseases, like heart disease and stroke, particularly identifying high-risk patients that current prediction tools miss.

9 May 2025

Firefighters and health care workers show elevated PFAS levels in new study

A study including researchers from the University of Arizona Health Sciences and published in the Journal of Exposure Science & Environmental Epidemiology found that firefighters had higher concentrations of certain per- and polyfluoroalkyl substances, or PFAS, and health care workers had moderate elevations of PFAS in their blood with significantly higher odds of two specific PFAS when compared with other essential workers.

8 May 2025

Long-acting HIV drug emerges from decades of research and advocacy

In the hunt for a remedy, when the baton is passed from dedicated academic scientists to an innovative company to trusted community advocates, outcomes for society can be especially powerful.

8 May 2025

Vitamin supplement slows glaucoma progression in animal studies

A vitamin supplement that improves metabolism in the eye appears to slow down damage to the optic nerve in glaucoma.

8 May 2025

Sleep deprivation increases inflammation linked to heart disease risk

Even a few nights with insufficient sleep increases promote molecular mechanisms linked to a greater risk of heart problems.

8 May 2025

Talking therapy by GPs eases PTSD symptoms after critical illness

A brief spell of talking therapy with a general practitioner reduces symptoms of post-traumatic stress disorder (PTSD) for survivors of critical illness, finds a trial from Germany published by The BMJ today.

8 May 2025

Next-generation "armored" CAR T cell therapy shows promising results in lymphoma patients

A next-generation "armored" CAR T cell therapy showed promising results in a small study of patients whose B-cell lymphomas continued to resist multiple rounds of other cancer treatments, including commercially available CAR T cell therapies.

8 May 2025

Anti-parasitic drug could accelerate the elimination of infection endemic to Africa

Tens of millions of people in Africa are infected by parasitic worms that cause lymphatic filariasis (also called elephantiasis), a disease that leads to severe swelling and deformities of the limbs and genitals.

7 May 2025

Low-dose rapamycin shows promise for enhancing healthspan in older adults

A new research paper was published in Aging (Aging-US) Volume 17, Issue 4, on April 4, 2025, titled "Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results."

7 May 2025

Progesterone-only contraceptive pill linked to increased asthma attacks in some women

A major study of around 260,000 women shows that taking the progesterone-only contraceptive pill can increase asthma attacks in some women.

7 May 2025

Precision medicine approach improves treatment for soft tissue sarcomas

A study conducted by researchers from the Agency for Science, Technology and Research (A*STAR), National Cancer Centre Singapore (NCCS) and National University of Singapore (NUS), in collaboration with biotech company, KYAN Technologies, has demonstrated that a precision medicine approach improves treatment selection for patients with soft tissue sarcomas (STS) in a clinical setting.

7 May 2025

Tomato and fruit juice improve quality of life for kids with asthma

Study suggests these antioxidant-rich juices may be a well-tolerated, practical addition to standard childhood asthma management.

6 May 2025

New therapy targets emotional processing to manage chronic pain

A new study led by UNSW Sydney and Neuroscience Research Australia (NeuRA) shows that targeting emotional processing is key to treating and managing chronic pain.

6 May 2025

Immunotherapy before and after surgery boost longer event-free survival in head and neck cancer

Patients with locally advanced head and neck cancer who received the immune checkpoint inhibitor pembrolizumab before, during and after standard-of-care surgery had longer event-free survival without the cancer coming back and higher rates of substantial tumor shrinkage prior to surgery, according to the first interim analysis of a randomized, open-label phase 3 clinical trial led by investigators from Dana-Farber Brigham Cancer Center and Washington University School of Medicine in St. Louis.

6 May 2025

MED13L Foundation funds groundbreaking study at Boston Children's Hospital

The MED13L Foundation today announced a nearly $250,000 grant to help launch an innovative natural history study at Boston Children's Hospital's Rosamund Stone Zander Translational Neuroscience Center (RSZ TNC).

5 May 2025

Combining vagus nerve stimulation with therapy provides lasting PTSD relief

In a first-of-its-kind clinical study, scientists at The University of Texas at Dallas and Baylor University Medical Center showed that patients with treatment-resistant PTSD were symptom-free up to six months after completing traditional therapy paired with vagus nerve stimulation (VNS).

5 May 2025

Breakthrough brain training shows promise for Long COVID recovery

Researchers at the University of Alabama at Birmingham (UAB) have identified what is believed to be the first intervention found in a randomized controlled trial to show large and very large improvements in multiple symptoms associated with Long COVID, and to result in people debilitated by those symptoms returning to work.

5 May 2025