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MaxCyte celebrates 25 years of innovation driving cell engineering-based therapeutics

MaxCyte, Inc., a leading, cell-engineering focused company providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell therapeutics, marks the 25th anniversary of its founding this year.

From MaxCyte, Inc. 13 Nov 2024

Scientists uncover cerebrospinal fluid markers for Alzheimer's detection and treatment

Researchers map the unique genetic regulation of proteins in human cerebrospinal fluid, identifying potential targets for Alzheimer’s treatments.

12 Nov 2024

Early genomic profiling improves cancer treatment outcomes

New real-world data from Providence, Illumina, and Microsoft Research reveals that Comprehensive Genomic Profiling (CGP), when done early in a cancer patient's diagnosis, leads to better personalized treatment and patient outcomes.

12 Nov 2024

Metabolic enzymes take on unexpected roles in cell division and DNA repair

Researchers at the Centre for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within the nucleus, orchestrating critical functions like cell division and DNA repair.

12 Nov 2024

Revolutionary AI predicts aging and disease from DNA patterns

Researchers developed CpGPT, a novel foundation model for DNA methylation analysis that captures sequence, positional, and epigenetic context to predict aging and disease risks. This model offers breakthroughs in imputing missing data and improving mortality and morbidity predictions.

11 Nov 2024

Breakthrough research reveals how to target malignant DNA in aggressive cancers

Scientists have discovered a way to target elusive circular fragments of DNA that drive the survival of some of the most aggressive cancers, paving the way for future treatments.

9 Nov 2024

Genetic diagnosis solves medical mystery for 30 undiagnosed patients

An international team of researchers has provided a genetic diagnosis for 30 individuals whose condition was undiagnosed for years despite extensive clinical or genetic testing.

8 Nov 2024

Exploring the protective effects of HSD17B13 in hepatic steatosis

Chronic liver disease (CLD) is a growing global health challenge, accounting for millions of deaths each year. Its major contributors include metabolic dysfunction-associated steatohepatitis (MASH), alcoholic liver disease (ALD), and hepatitis C virus infection.

8 Nov 2024

New insights into the genetic legacy of Denisovans

Scientists believe individuals of the most recently discovered "hominin" group (the Denisovans) that interbred with modern day humans passed on some of their genes via multiple, distinct interbreeding events that helped shape early human history.

8 Nov 2024

CRISPR technology reveals essential noncoding RNAs in the human genome

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins.

7 Nov 2024

New antibiotic-resistant bacteria strain may be spreading across Asia

A virulent new strain of antibiotic-resistant bacteria that causes severe disease could be spreading widely across Asia - posing significant challenges to global public health, a new study reveals.

7 Nov 2024

Researchers find 41 new genetic regions linked to disc herniations

Lumbar disc herniation is one of the most common structural changes in the lower back and the most common cause of radiating pain, or sciatica, in the leg.

7 Nov 2024

Gene editing with CRISPR may introduce new defects

The CRISPR tool is capable of repairing the genetic defect responsible for the immune disease chronic granulomatous disease.

6 Nov 2024

CHiTA assay identifies functional twister ribozymes

The "RNA world" hypothesis proposes that the earliest life on Earth may have been based on RNA - a single-stranded molecule similar in many ways to DNA - like some modern viruses. This is because, like DNA, RNA can carry genetic information, but, like a protein, it can also act as an enzyme, initiating or accelerating reactions.

5 Nov 2024

New insights into the role of innate immunity in tumor initiation

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in unexpected ways - ways that have important implications for the development of cancer, researchers at Memorial Sloan Kettering Cancer Center (MSK) are discovering.

5 Nov 2024

Multi-omics-based classification of gastrointestinal stromal tumors lays groundwork for precision treatment

A recent study offering a comprehensive view of the genome and transcriptome of gastrointestinal stromal tumors (GISTs) has introduced a new, multi-omics-based molecular classification of these tumors.

5 Nov 2024

Werner syndrome gene plays key role in maintaining cellular organization and DNA stability

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 20 on October 17, 2024, entitled, "Werner syndrome RECQ helicase participates in and directs maintenance of the protein complexes of constitutive heterochromatin in proliferating human cells."

5 Nov 2024