Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Researchers discover dual-functional compound that shows potential to combat type 1, type 2 diabetes

According to research published online in The FASEB Journal, scientists have discovered a dual peptide called "PGLP-1" that promotes insulin secretion and inhibits gluconeogenesis.

11 May 2017

Breast cancer drug offers protection against obesity-related metabolic disorders

Tamoxifen, a selective estrogen receptor modulator, is the gold standard for endocrine treatment of estrogen-receptor positive breast cancer.

11 May 2017

Specific genotype may predict recovery in patients with advanced cirrhosis after hepatitis c treatment

Genotyping of patients with advanced cirrhosis from hepatitis C virus could help health-care professionals predict the likelihood of improvement after successful hepatitis C treatment, thus minimizing the need for liver transplants.

8 May 2017

New review explains how calorie restriction can extend life

A new review proposes a theory to explain how calorie restriction can extend life across a variety of species.

3 May 2017

Impaired effects of insulin can increase cancer risk, shows study

Over the decades, scientists have repeatedly shown that patients with increased levels of the hormone insulin in their blood can experience increased risks of cancer. Surprisingly, however, Joslin Diabetes Center researchers now have discovered that impaired effects of insulin also can boost these risks.

3 May 2017

Study reveals promising results for primary liver cancer patients treated with SIR-Spheres Y-90 resin microspheres

Patients with advanced or inoperable Hepatocellular Carcinoma (HCC) who usually received one or two treatments with liver-directed SIR-Spheres Y-90 resin microspheres in the 459-patient French SARAH study had similar survival compared to patients who received standard twice-daily systemic treatment with sorafenib, but with less than half the number and significantly fewer severe treatment-related adverse effects and significantly better Quality of Life, according to data presented here at The International Liver Congress™ 2017.

26 Apr 2017

Vitamin A combined with high-fat diet may lead to increased risk for obesity and diabetes

Vitamin A is an essential nutrient that the human body needs to function properly. But new research presented today at the American Physiological Society annual meeting at Experimental Biology 2017 in Chicago suggests that normal levels of vitamin A within a high-fat diet can negatively affect expression of liver genes associated with glucose and fat metabolism.

26 Apr 2017

High-fat diet and obesity drive liver immune cells to promote metabolic syndrome

A high-fat diet and obesity turn "hero" virus-fighting liver immune cells "rogue", leading to insulin resistance, a condition that often results in type 2 diabetes, according to research published today in Science Immunology.

21 Apr 2017

New study reveals sympathetic nervous system as main driver of thermogenesis

A new study from the Icahn School of Medicine at Mount Sinai provides important insights into how the body regulates its production of heat, a process known as thermogenesis that is currently intensely studied as a target of diabetes and obesity treatment in humans.

17 Apr 2017

Scientists discover how insulin-producing cells show differences in age

Diabetes researchers have puzzled for decades about why insulin-producing beta cells in one pancreatic islet often look and behave quite differently than their counterparts in the same islet or in nearby islets.

12 Apr 2017

Metabolite produced by intestinal bacteria protects against type 2 diabetes, study shows

A high concentration of indolepropionic acid in the serum protects against type 2 diabetes, shows a new study from the University of Eastern Finland. Indolepropionic acid is a metabolite produced by intestinal bacteria, and its production is boosted by a fibre-rich diet.

11 Apr 2017

Metabolic syndrome is the new 'silent killer', warn researchers

For decades, American waistlines have been expanding and there is increasing cause for alarm. Researchers from the Charles E. Schmidt College of Medicine at Florida Atlantic University make the case that metabolic syndrome -- a cluster of three of more risk factors that include abdominal obesity, high triglycerides, high blood pressure, abnormal lipids, and insulin resistance, a precursor of type 2 diabetes -- is the new "silent killer," analogous to hypertension in the 1970s.

6 Apr 2017

HIIT increases glucose metabolism and insulin sensitivity in diabetics, research reveals

New research reveals that high-intensity interval training (HIIT) increases glucose metabolism in muscles as well as insulin sensitivity in type 2 diabetes. Already after a two-week training period, the glucose uptake in thigh muscles returned to a normal level.

6 Apr 2017

Insulin Resistance News and Research

Further Reading

Researchers discover dual-functional compound that shows potential to combat type 1, type 2 diabetes

Breast cancer drug offers protection against obesity-related metabolic disorders

Specific genotype may predict recovery in patients with advanced cirrhosis after hepatitis c treatment

New review explains how calorie restriction can extend life

Impaired effects of insulin can increase cancer risk, shows study

Study reveals promising results for primary liver cancer patients treated with SIR-Spheres Y-90 resin microspheres

Vitamin A combined with high-fat diet may lead to increased risk for obesity and diabetes

High-fat diet and obesity drive liver immune cells to promote metabolic syndrome

New study reveals sympathetic nervous system as main driver of thermogenesis

Scientists discover how insulin-producing cells show differences in age

Metabolite produced by intestinal bacteria protects against type 2 diabetes, study shows

Metabolic syndrome is the new 'silent killer', warn researchers

HIIT increases glucose metabolism and insulin sensitivity in diabetics, research reveals

Cellular markers of aging could reveal how insulin-producing cells begin to fail in type 2 diabetes

Newly-discovered mechanism for compound may help prevent neurologic damage

Liver shows positive response to leptin therapy in patients with partial lipodystrophy, study finds

Unique metabolic ‘signature’ in urine may help predict development of diabetes in obese teenagers

Switching off glucocorticoid signaling in bone could protect against diet-induced metabolic disturbances

Weight gain within healthy BMI range increases gestational diabetes risk in women

Fighting colorectal cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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