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Protein alteration contributes to degeneration of neuronal populations in Huntington's disease

Protein alteration in the family of lamins causes several diseases, known as laminopathies, such as progeria or precocious aging.

1 Feb 2021

Study details how glutamate signaling works in the brain to enable neuronal communication

The most powerful substance in the human brain for neuronal communication is glutamate. It is by far the most abundant, and it's implicated in all kinds of operations.

30 Jan 2021

Study finds locations of early prion protein accumulation in the eye

The earliest eye damage from prion disease takes place in the cone photoreceptor cells, specifically in the cilia and the ribbon synapses, according to a new study of prion protein accumulation in the eye by National Institutes of Health scientists.

29 Jan 2021

Researchers use new imaging technique to understand motor deficits in ALS disease

An interdisciplinary team of the Institut national de la recherche scientifique (INRS) used an innovative imaging technique for a better understanding of motor deficits in Amyotrophic Lateral Sclerosis (ALS).

29 Jan 2021

Neural network models mimic the behavior of real dendrites

Neurons, the fundamental units of the brain, are complex computers by themselves. They receive input signals on a tree-like structure - the dendrite.

27 Jan 2021

£1.6 million grant awarded to advance development of MND drug candidate

Researchers from the University of Sheffield's Institute for Translational Neuroscience have been awarded a £1.6 million grant from the Medical Research Council.

26 Jan 2021

Brain stimulation highlights ancestral brain highway system shared by humans and monkeys

Scientists have identified that the evolutionary development of human and primate brains may have been similar for communication and memory.

25 Jan 2021

Scientists discover mechanism for transient memory lapse

In a landmark neurobiology study, scientists from Scripps Research have discovered a memory gating system that employs the neurotransmitter dopamine to direct transient forgetting, a temporary lapse of memory which spontaneously returns.

21 Jan 2021

Using gene therapy to mimic the effects of physical exercise

It sounds too good to be true - and it is. But Jose Bianco Moreira and the CERG research group at the Norwegian University of Science and Technology are convinced that some of the positive health effects of physical exercise can be achieved using gene therapy and medication.

21 Jan 2021

New sensory neuron model enables easy generation of cells to fast-track pain research

Scientists have for the first time established a sensory neuron model able to mass-reproduce two key sensory neuron types involved in pain sensation, enabling the easy generation of large numbers of the cells to fast-track chronic pain research.

21 Jan 2021

Size of synapses determines the strength of information transmission

Nerve cells communicate with one another via synapses. Neuroscientists at the University of Zurich and ETH Zurich have now found that these connections seem to be much more powerful than previously thought.

21 Jan 2021

Can transgenic mice studies illuminate neurological complications associated with SARS-CoV-2 in humans?

The potentially deadly COVID-19 has not affected animals with corresponding severity. To understand the mechanism of severe disease, animal models have been used. This includes a mouse model that expresses human angiotensin-converting enzyme 2 (hACE2) under the cytokeratin 18 promoter (K18-hACE2). A new study indicates that this may not be a faithful model of human lethal infection with SARS-CoV-2.

18 Jan 2021

No inflammation of cerebrospinal fluid in COVID-19 patients with neurological features, study finds

Many patients with COVID-19 have shown neurological complications, leading to scientific interest in the role played by its causative pathogen, SARS-CoV-2, in brain inflammation. A new study has described the absence of neuroinflammation in cerebrospinal fluid (CSF).

14 Jan 2021

Study shows how brain molecules work in conjunction to create architectural marvels

In a study published in Cell Reports, researchers at Kanazawa University identify pathways in the brain which enable neurons to assemble into functional units resembling tall columns.

12 Jan 2021

Researchers develop improved process for large-scale electron microscopy to visualize small structures

How are networks of neurons connected to make functional circuits? This has been a long-standing question in neuroscience. To answer this fundamental question, researchers from Boston Children's Hospital and Harvard Medical School developed a new way to study these circuits and in the process learn more about the connections between them.

12 Jan 2021

Wireless medical device might help with weight loss

Gastric bypass surgery is sometimes the last resort for those who struggle with obesity or have serious health-related issues due to their weight.

8 Jan 2021

Novel coloring technique helps identify each neuron in the worm's nervous system

The human brain contains approximately 86 billion neurons, or nerve cells, woven together by an estimated 100 trillion connections, or synapses. Each cell has a role that helps us to move muscles, process our environment, form memories, and much more.

8 Jan 2021

CytoDel successfully delivers neuronal antibody in animal models of botulism

CytoDel, Inc., a privately-held corporation, today announces the publication of preclinical data on the Company's lead product, Cyto-111, in the peer-reviewed journal, Science Translational Medicine. The complete text of the article titled, "Neuronal Delivery of Antibodies has Therapeutic Effects in Animal Models of Botulism," can be found here.

7 Jan 2021

Non-toxic versions of botulism toxins can deliver therapeutic antibodies to treat botulism

Taking advantage of the chemical properties of botulism toxins, two teams of researchers have fashioned non-toxic versions of these compounds that can deliver therapeutic antibodies to treat botulism, a potentially fatal disease with few approved treatments.

6 Jan 2021

Study: Decreased activation of LEF1 gene disrupts ordinary neuronal function

Lithium is considered the gold standard for treating bipolar disorder (BD), but nearly 70 percent of people with BD don't respond to it.

5 Jan 2021

Neuron News and Research

Protein alteration contributes to degeneration of neuronal populations in Huntington's disease

Study details how glutamate signaling works in the brain to enable neuronal communication

Study finds locations of early prion protein accumulation in the eye

Researchers use new imaging technique to understand motor deficits in ALS disease

Neural network models mimic the behavior of real dendrites

£1.6 million grant awarded to advance development of MND drug candidate

Brain stimulation highlights ancestral brain highway system shared by humans and monkeys

Scientists discover mechanism for transient memory lapse

Using gene therapy to mimic the effects of physical exercise

New sensory neuron model enables easy generation of cells to fast-track pain research

Size of synapses determines the strength of information transmission

Can transgenic mice studies illuminate neurological complications associated with SARS-CoV-2 in humans?

No inflammation of cerebrospinal fluid in COVID-19 patients with neurological features, study finds

Study shows how brain molecules work in conjunction to create architectural marvels

Researchers develop improved process for large-scale electron microscopy to visualize small structures

Wireless medical device might help with weight loss

Novel coloring technique helps identify each neuron in the worm's nervous system

CytoDel successfully delivers neuronal antibody in animal models of botulism

Non-toxic versions of botulism toxins can deliver therapeutic antibodies to treat botulism

Study: Decreased activation of LEF1 gene disrupts ordinary neuronal function

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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