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Study shows how RNA editing affects the replication of COVID-19 virus

Two human deaminase enzymes edit the RNA of the SARS-CoV-2 virus when it enters a patient's body, with implications for the evolution of the virus and the spread of the infection, according to a new study.

19 May 2020

Study shows how cancer protein changes may accelerate tumorigenesis and metastasis

Understanding the genetic mutations and protein changes that take place in the progression of cancer is key to its treatment. Mutations in the gene TP53 and concomitant mutant p53 proteins in cancer cells have become notorious over the course of multiple studies of several different types of cancers.

18 May 2020

New analysis links DNA variations to risks of specific breast cancer subtypes

An analysis of genetic studies covering 266,000 women has revealed 32 new sites on the human genome where variations in DNA appear to alter the risks of getting breast cancer.

18 May 2020

Researchers reveal the molecular biology behind Hyaline Fibromatosis Syndrome

Hyaline Fibromatosis Syndrome (HFS) is a rare but severe genetic disease that affects babies, children, and adults. Hyaline, a glassy substance, accumulates in the skin and various organs, and causes painful deformities that can lead to an early death.

18 May 2020

Fibroblasts of different pancreatic diseases exhibit distinct properties, study reveals

Fibroblasts present in different pancreatic diseases are genetically distinct and their functions are 'programmed' by the unique environment of each disease, according to new research from the University of Liverpool (UK).

18 May 2020

Cancer biologists identify important drivers of tumor resistance

Cancer biologists at the Mays Cancer Center, home to UT Health San Antonio MD Anderson, have identified important drivers that enable tumors to change their behavior and evade anticancer therapies.

18 May 2020

Cross-neutralization of SARS and COVID-19 coronaviruses by a monoclonal antibody

An antibody first identified in a blood sample from a patient who recovered from Severe Acute Respiratory Syndrome in 2003 inhibits related coronaviruses, including the cause of COVID-19.

18 May 2020

Study: 3 to 5% of children with an aunt or uncle with ASD may have autism

Roughly 3 to 5% of children with an aunt or uncle with autism spectrum disorder (ASD) can also be expected to have ASD, compared to about 1.5% of children in the general population, according to a study funded by the National Institutes of Health. Researchers also found that a child whose mother has a sibling with ASD is not significantly more likely to be affected by ASD, compared to a child whose father has a sibling with ASD.

18 May 2020

Oxford University vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

As the world continues to grapple with the coronavirus pandemic, many scientists, institutions, and pharmaceutical companies are working hard to develop an effective vaccine.

18 May 2020

Kawasaki disease outbreak in children with COVID-19

The ongoing COVID-19 pandemic has marched its way to almost all parts of the world, with hundreds of thousands of deaths and over 4.5 million cases as of May 15, 2020. One saving grace has been the apparent sparing of children, though the mortality in older people is quite high.

17 May 2020

Host-virus interaction drives adaptive mutation in bat CoV related to SARS-CoVs

Virus and receptor diversity is shaped by the need to evolve advanced weaponry to facilitate virus entry and infection, on the one hand, and host resistance, on the other. A new paper published on the preprint server bioRxiv* shows how this mechanism operates in a bat coronavirus, which is related to the earlier SARS coronavirus.

17 May 2020

New algorithm could help investigate the genetic clues behind immunity

Scientists with UC San Diego's Jacobs School of Engineering and the Qualcomm Institute have developed a new gene prediction algorithm, called MINING-D, that could help researchers investigate the genetic clues behind the variation of symptoms shown in COVID-19 patients - information that is key to creating a versatile and effective vaccine.

15 May 2020

Transition to virtual care during COVID-19 does not limit glycemic outcomes of diabetes inpatients

Data collected over a 15-week period showed that using virtual care to manage diabetes patients in the hospital does not have a negative impact on their glycemic outcomes.

15 May 2020

New book demystifies the molecular biology of breast cancer

Breast cancer is known as one of the most deadly diseases among women. However, recent advancements in the imaging tools and diagnostic methods for breast cancer has improved the screening in the past few years.

15 May 2020

Study shows the combined effect of inherited and acquired mutations on cancer development

The common belief that tumors arise via activation of a few genes that "drive" cancer development is unsupported by a widespread investigation into those genes and others in three large patient genetic databases, according to a study led by Yale Cancer Center researchers.

15 May 2020

Forensic Genomics to launch preview issue at annual ISHI

Forensic Genomics, a dynamic new peer-reviewed journal, will launch its preview issue at the annual International Symposium on Human Identification (ISHI) in September 2020.

15 May 2020

Digital technology applications will play a key role in addressing COVID-19 crisis

Artificial intelligence, machine learning, blockchain, and other key digital technology applications will play a vital role addressing the new healthcare challenges triggered by the COVID-19 pandemic, according to a peer-reviewed Special Issue of OMICS: A Journal of Integrative Biology.

15 May 2020

More research is needed to determine if fecal matter spreads COVID-19, say researchers

Early studies show evidence of COVID-19 genetic material in fecal matter, but more work is needed to determine if the virus can be spread through stool, according to a new review paper from a Rice University epidemiologist.

15 May 2020

Activity of malaria-causing parasite is driven by the parasite's own inherent clocks

The activity of the parasite that causes malaria is driven by the parasite's own inherent clock, new research led by UT Southwestern scientists suggests. The findings, published this week in Science, could lead to new ways to fight this pervasive and deadly disease.

15 May 2020

Research investigates COVID-19 virus origin using artificial intelligence (AI)

The coronavirus responsible for the COVID-19 pandemic has spread across the globe with unprecedented speed and lethality, killing hundreds of thousands of people and forcing countries’ entire populations to self-quarantine.

15 May 2020

Genetic News and Research

Study shows how RNA editing affects the replication of COVID-19 virus

Study shows how cancer protein changes may accelerate tumorigenesis and metastasis

New analysis links DNA variations to risks of specific breast cancer subtypes

Researchers reveal the molecular biology behind Hyaline Fibromatosis Syndrome

Fibroblasts of different pancreatic diseases exhibit distinct properties, study reveals

Cancer biologists identify important drivers of tumor resistance

Cross-neutralization of SARS and COVID-19 coronaviruses by a monoclonal antibody

Study: 3 to 5% of children with an aunt or uncle with ASD may have autism

Oxford University vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

Kawasaki disease outbreak in children with COVID-19

Host-virus interaction drives adaptive mutation in bat CoV related to SARS-CoVs

New algorithm could help investigate the genetic clues behind immunity

Transition to virtual care during COVID-19 does not limit glycemic outcomes of diabetes inpatients

New book demystifies the molecular biology of breast cancer

Study shows the combined effect of inherited and acquired mutations on cancer development

Forensic Genomics to launch preview issue at annual ISHI

Digital technology applications will play a key role in addressing COVID-19 crisis

More research is needed to determine if fecal matter spreads COVID-19, say researchers

Activity of malaria-causing parasite is driven by the parasite's own inherent clocks

Research investigates COVID-19 virus origin using artificial intelligence (AI)

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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