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Researchers develop oral vaccine against Helicobacter pylori

Researchers from Southern Medical University in Guangdong, Guangzhou, China, have developed an oral vaccine against Helicobacter pylori, the bacteria responsible for peptic ulcers and some forms of gastric cancer, and have successfully tested it in mice. The research is published ahead of print in the journal Clinical and Vaccine Immunology.

20 Dec 2013

BCG vaccine highly protective against pulmonary TB: Study

The BCG vaccine has been found to be more effective against the most common form of tuberculosis than previously thought, according to a new study in Clinical Infectious Diseases.

20 Dec 2013

Takeda to acquire exclusive license to develop Natrogen's Natura-alpha compound

Takeda Pharmaceutical Company Limited and Natrogen Therapeutics International, Inc. jointly announced today an agreement whereby Takeda will acquire an exclusive license to develop Natrogen's Natura-alpha compound as well as an option to acquire Natrogen. Natura-alpha is a synthetic small molecule oral compound that is believed to inhibit pro-inflammatory cytokine expression, which may help to reduce gastrointestinal inflammation. Natura-alpha is currently in Phase 2 development for the treatment of ulcerative colitis.

20 Dec 2013

Researchers receive 3 Patient-Centered Outcomes Research Institute awards from PCORI

Research teams at Group Health Research Institute have been approved for funding awards by the Patient-Centered Outcomes Research Institute (PCORI) to study opioid therapy and asthma-and to help expand a health data network that will be part of PCORnet: the National Patient-Centered National Clinical Research Network.

20 Dec 2013

Some Americans reflect on insurance they had pre-health law

Americans who are slated to have new insurance from the health law are reflecting on what their old coverage was like -- if they had it at all. Also, an architect of the Massachusetts health law reflects on the federal health law.

20 Dec 2013

Patient assessment of clinical services quality predicts survival for colorectal cancer patients

Patient assessment of clinical services quality was shown to be an independent predictor of survival for colorectal cancer patients in a study recently published in the Journal of Healthcare Quality, the peer reviewed publication of the National Association for Healthcare Quality (NAHQ), www.nahq.org.

20 Dec 2013

Study finds 87% of teens who quit chewing gum experience relief of migraine headache

Teenagers are notorious for chewing a lot of gum. The lip smacking, bubble popping, discarded gum stuck to the sole give teachers and parents a headache.

20 Dec 2013

Researchers receive Doris Duke Foundation award to predict sickle cell crisis, monitor treatments

Researchers at Case Western Reserve University have received a $486,000 Doris Duke Foundation award to discover how to predict when sickle cell disease patients will suffer an acute crisis and monitor the effectiveness of treatments.

20 Dec 2013

Congress closes in on permanent fix to Medicare doctor payments

With a bipartisan budget deal behind it, Congress may be on the verge of solving the way it makes Medicare payments to doctors. Meanwhile, national spending on health care is growing at the slowest pace ever recorded, according to The New York Times.

19 Dec 2013

Blaze Bioscience to initiate first Phase 1 clinical study of BLZ-100 in patients with skin tumors

Blaze Bioscience, Inc. and its subsidiary, Blaze Bioscience Australia Pty Ltd, today announced the initiation of the first Phase 1 clinical study of the first Tumor Paint product candidate, BLZ-100. The study, titled "A Phase I Dose Escalation/Expansion Study of BLZ-100 Administered by Intravenous Injection in Adult Subjects with Skin Cancer," will enroll up to 30 patients with basal cell carcinoma, squamous cell carcinoma, or amelanotic melanoma.

19 Dec 2013

Copenhagen scientists study link between congenital arrhythmia and hypoglycemia

In a new study, scientists from University of Copenhagen document a connection between congenital arrhythmia and the bodies' ability to handle sugar. The results can be of vital importance for patients with the disease and for the future treatment of diabetes. The new study has just been published in the scientific journal Diabetes.

19 Dec 2013

Study shows that gaining too little weight during pregnancy is risk factor for infant mortality

Women who do not gain enough weight during pregnancy are at increased risk of losing their baby in its first year of life, according to a new study by researchers in the University of Maryland School of Public Health.

19 Dec 2013

Researchers map cell's complex genetic interactions to fix UV damaged DNA

Researchers at the University of California, San Diego School of Medicine, with colleagues in The Netherlands and United Kingdom, have produced the first map detailing the network of genetic interactions underlying the cellular response to ultraviolet (UV) radiation.

19 Dec 2013

EORTC, GIMEMA clinical trial results show high-dose cytarabine improves outcome in AML patients

Results of the EORTC and GIMEMA AML-12 Trial appearing in the Journal of Clinical Oncology show that high-dose cytarabine in induction treatment improves outcome of adult patients with acute myeloid leukemia.

19 Dec 2013

GSK team wins Drug Discovery of Year award for developing trametinib for malignant melanoma

The British Pharmacological Society proudly announces that its Drug Discovery of the Year award has been won by the team at GlaxoSmithKline (GSK) responsible for the development of trametinib - a new treatment for malignant melanoma (a type of skin cancer).

19 Dec 2013

Childhood asthma secondhand smoke education vital

A US study has found that smokers caring for children with asthma often underestimate levels of secondhand smoke exposure.

19 Dec 2013

Hispanic mortality paradox found in RA patients

The so-called “Hispanic survival paradox” has been found to extend to patients with rheumatoid arthritis, whereby Hispanic people with the condition tend have more severe symptoms but equivalent mortality to non-Hispanic White individuals.

19 Dec 2013

Diet may not fully explain cardiometabolic problems in bipolar disorder

The diet of patients with bipolar disorder or schizophrenia seems to be no worse than that of mentally healthy people, a study suggests.

19 Dec 2013

MEDNAX acquires Neonatology Center of Winchester

MEDNAX, Inc., today announced the acquisition of Neonatology Center of Winchester, P.C., a neonatal physician group practice based in Winchester, Va. The practice will become part of MEDNAX's Pediatrix Medical Group division, a national group practice consisting of the nation's leading neonatal, maternal-fetal medicine, pediatric cardiology, and other pediatric specialty physicians.

19 Dec 2013

Daiichi Sankyo submits LIXIANA supplemental NDA for review in Japan

Daiichi Sankyo Company, Limited (hereafter, Daiichi Sankyo) today announced that it has submitted a supplemental New Drug Application for its oral, once-daily direct factor Xa-inhibitor LIXIANA® (Edoxaban Tosilate Hydrate) for review by the Japanese Ministry of Health, Labour and Welfare. Daiichi Sankyo is seeking approval in Japan for edoxaban in new indications for non-valvular atrial fibrillation and symptomatic venous thromboembolism.

19 Dec 2013

Research News and Research

Researchers develop oral vaccine against Helicobacter pylori

BCG vaccine highly protective against pulmonary TB: Study

Takeda to acquire exclusive license to develop Natrogen's Natura-alpha compound

Researchers receive 3 Patient-Centered Outcomes Research Institute awards from PCORI

Some Americans reflect on insurance they had pre-health law

Patient assessment of clinical services quality predicts survival for colorectal cancer patients

Study finds 87% of teens who quit chewing gum experience relief of migraine headache

Researchers receive Doris Duke Foundation award to predict sickle cell crisis, monitor treatments

Congress closes in on permanent fix to Medicare doctor payments

Blaze Bioscience to initiate first Phase 1 clinical study of BLZ-100 in patients with skin tumors

Copenhagen scientists study link between congenital arrhythmia and hypoglycemia

Study shows that gaining too little weight during pregnancy is risk factor for infant mortality

Researchers map cell's complex genetic interactions to fix UV damaged DNA

EORTC, GIMEMA clinical trial results show high-dose cytarabine improves outcome in AML patients

GSK team wins Drug Discovery of Year award for developing trametinib for malignant melanoma

Childhood asthma secondhand smoke education vital

Hispanic mortality paradox found in RA patients

Diet may not fully explain cardiometabolic problems in bipolar disorder

MEDNAX acquires Neonatology Center of Winchester

Daiichi Sankyo submits LIXIANA supplemental NDA for review in Japan

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