Clinical Trial News and Research

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New blood test can predict which heart failure patients would benefit from ICDs

A novel blood test that predicts sudden death risk in heart failure patients is set to help physicians decide which patients would benefit from implantable cardioverter defibrillators (ICDs).

27 Aug 2012

New data from Boehringer Ingelheim and Pfizer's tiotropium clinical studies on asthma, COPD

New data to be presented at the Annual Congress of the European Respiratory Society (ERS 2012), in Vienna, Austria, will shed light on the current and potential future role of tiotropium, the first once-daily long-acting inhaled anticholinergic for patients with Chronic Obstructive Pulmonary Disease (COPD).

27 Aug 2012

Trevo Retriever effectively removes blood clots in patients with stroke

Every 40 seconds, someone in the United States has a stroke, usually caused when a clot blocks an artery that supplies blood to the brain. Now the results of two multicenter studies published online in The Lancet on August 26 are giving physicians new innovative tools proven to better remove these clots that block blood flow.

26 Aug 2012

Seattle Genetics commences everolimus-SGN-75 combination phase Ib clinical trial for advanced RCC

Seattle Genetics, Inc. today announced the initiation of a phase Ib clinical trial evaluating SGN-75 in combination with everolimus (Afinitor) for patients with advanced metastatic renal cell carcinoma (RCC).

24 Aug 2012

Diabetes journal reports results from novel experimental therapy

Results from a novel experimental therapy for Type 1 diabetes that boosts parts of the healthy immune system are reported today in the scientific journal Diabetes.

24 Aug 2012

Survival rate for African-American men with prostate cancer now comparable to Caucasians

The routine use of prostate specific antigen (PSA) testing for screening and monitoring prostate cancer has led to early and more sensitive detection of the disease. A new study published in The Journal of Urology- reports that in the "PSA era," survival has improved for patients with newly diagnosed prostate cancer that has spread to the bones or other parts of the body and the disparity between African American and Caucasian men has been resolved.

24 Aug 2012

Sapheon completes $18.5M Series B Preferred equity offering

Sapheon Inc. has completed the first closing in its $18.5 million Series B Preferred equity offering. The Company issued 4,775,291 shares worth $8.6 million to Series B purchasers and convertible notes holders.

24 Aug 2012

NW Bio receives MHRA approval to initiate DCVax-L Phase III GBM brain cancer trial in the U.K.

Northwest Biotherapeutics announced today that it has received approval from the Medicines and Healthcare Products Regulatory Agency (MHRA) of the United Kingdom, for the Company's 300-patient Phase III clinical trial of DCVax-L immune therapy for Glioblastoma multiforme brain cancer (GBM) to proceed in the U.K.

24 Aug 2012

AcelRx commences third ARX-01 Phase 3 study in post-operative pain

AcelRx Pharmaceuticals, Inc., a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for the treatment of acute and breakthrough pain, today announced dosing of the first patient in the third of three planned Phase 3 studies for ARX-01, the Sufentanil NanoTab PCA System, its novel sublingual patient-controlled analgesia (PCA) system.

24 Aug 2012

Blood clotting treatment algorithms help decrease transfusion requirements in cardiac surgery patients

In patients who undergo cardiac surgery, severe perioperative bleeding and its treatment are often associated with increases in major cardiac and non-cardiac adverse events and greater mortality. A study from the September issue of Anesthesiology determined certain blood clotting treatment algorithms helped decrease blood transfusion requirements in cardiac surgery patients and were associated with improved outcomes and hospital cost-savings.

23 Aug 2012

Aeras, IDRI announce start of first ID93 + GLA-SE Phase I trial for tuberculosis

Aeras and the Infectious Disease Research Institute (IDRI) announce today the start of the first clinical trial of IDRI's novel tuberculosis vaccine candidate, ID93 + GLA-SE.

23 Aug 2012

Common diabetes treatment may cause bladder cancer

A commonly used diabetes treatment may increase patients’ risk for bladder cancer, show US study findings.

22 Aug 2012

Final data from Symphogen's rozrolimupab Phase 2 trial on primary immune thrombocytopenia

The hematology journal BLOOD published today a full-length article describing final Phase 2 data for Symphogen's rozrolimupab, a novel human recombinant mixture of 25 antibodies which all are manufactured simultaneously from a single batch.

22 Aug 2012

Clinical trial to test whether fecal transplantation is effective in treating relapsing C. difficile

For patients with Clostridium difficile (C. difficile), a persistent and potentially deadly bacterial illness, severe diarrhea, abdominal pain, nausea and vomiting are an everyday event. This particularly virulent infection is prone to recurrence, even after multiple courses of expensive antibiotics, and treatment options are limited for patients who continually relapse or develop antibiotic resistance.

22 Aug 2012

Research explores impact of radiotherapy in older women with low risk of breast cancer recurrence

A Rhode Island Hospital radiation oncologist says in a new editorial that research exploring the impact of radiotherapy in older women with low risk of breast cancer recurrence has little effect on actual clinical decisions.

22 Aug 2012

VolitionRX to initiate NuQ blood-based tests in colorectal cancer clinical trial

VolitionRX Limited, a life sciences company focused on developing blood-based diagnostic tests, announces that its subsidiary Belgian Volition has signed an agreement with the Biobank of CHU UCL Mont-Godinne, an academic hospital in Yvoir, Belgium.

22 Aug 2012

Healthcare announces important changes to the U.S. product label for Optison

GE Healthcare today announced important changes to the U.S. product label for Optison (Perflutren Protein-Type A Microspheres Injectable Suspension, USP), a contrast agent that may improve the visualization of the left ventricular border - an area of the heart that is critical to see in order to diagnose certain heart diseases such as hypertrophic cardiomyopathy.

22 Aug 2012

Gene therapy applied to peripheral arterial disease

Hepatocyte growth factor gene therapy could be used to treat patients with severe peripheral arterial disease, suggest results of a phase I clinical trial.

21 Aug 2012

Tips for menopause symptom relief

An estimated 6,000 women in the U.S. reach menopause every day (about two million annually).The most common menopausal complaints include hot flashes, sleep disturbances, anxiety, poor mood, and physical and mental exhaustion. Hot flashes affect 80 percent of peri- or postmenopausal women, with 30 percent reporting hot flashes severe enough to seriously affect their quality of life.

21 Aug 2012

New tool reveals surprising clues about how cancer cells respond to therapy

A new tool to observe cell behavior has revealed surprising clues about how cancer cells respond to therapy, and may offer a way to further refine personalized cancer treatments.

21 Aug 2012

Clinical Trial News and Research

New blood test can predict which heart failure patients would benefit from ICDs

New data from Boehringer Ingelheim and Pfizer's tiotropium clinical studies on asthma, COPD

Trevo Retriever effectively removes blood clots in patients with stroke

Seattle Genetics commences everolimus-SGN-75 combination phase Ib clinical trial for advanced RCC

Diabetes journal reports results from novel experimental therapy

Survival rate for African-American men with prostate cancer now comparable to Caucasians

Sapheon completes $18.5M Series B Preferred equity offering

NW Bio receives MHRA approval to initiate DCVax-L Phase III GBM brain cancer trial in the U.K.

AcelRx commences third ARX-01 Phase 3 study in post-operative pain

Blood clotting treatment algorithms help decrease transfusion requirements in cardiac surgery patients

Aeras, IDRI announce start of first ID93 + GLA-SE Phase I trial for tuberculosis

Common diabetes treatment may cause bladder cancer

Final data from Symphogen's rozrolimupab Phase 2 trial on primary immune thrombocytopenia

Clinical trial to test whether fecal transplantation is effective in treating relapsing C. difficile

Research explores impact of radiotherapy in older women with low risk of breast cancer recurrence

VolitionRX to initiate NuQ blood-based tests in colorectal cancer clinical trial

Healthcare announces important changes to the U.S. product label for Optison

Gene therapy applied to peripheral arterial disease

Tips for menopause symptom relief

New tool reveals surprising clues about how cancer cells respond to therapy

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