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Bevacizumab–erlotinib combined efficacy may depend on VEGF level

Bevacizumab may enhance the antitumour activity of erlotinib by increasing the intratumoural concentration of erlotinib in some non-small-cell lung cancers expressing high levels of vascular endothelial growth factor, Japanese researchers report.

13 Nov 2014

Eye screenings of underserved populations reveal one in five has early stage diabetic retinopathy

Eye screenings of people with diabetes in underserved communities revealed that one in five had early stage diabetic retinopathy, according to a new study by a research consortium including investigators at the University of Alabama at Birmingham.

13 Nov 2014

Experimental Ebola treatments to be trialled in West Africa next month

Médecins Sans Frontières/Doctors without Borders (MSF) have announced that three trials of Ebola therapies will begin in West Africa this December.

13 Nov 2014

Unique immunochemotherapy approach to treating pancreatic cancer

VCU Massey Cancer Center and VCU Institute of Molecular Medicine researchers discovered a unique approach to treating pancreatic cancer that may be potentially safe and effective. The treatment method involves immunochemotherapy - a combination of chemotherapy and immunotherapy, which uses the patient's own immune system to help fight against disease.

13 Nov 2014

Amedica, Spinal Kinetics sign multi-year OEM agreement for silicon nitride spinal implants

Amedica Corporation, a biomaterial company that has developed silicon nitride ceramics as a material platform to manufacture and commercialize orthopedic implants, is pleased to announce that it has entered into a multi-year original equipment manufacturer (OEM) agreement with Spinal Kinetics, a leading innovator of advanced spinal implant technologies.

12 Nov 2014

UM researchers develop novel, family-focused, culturally-informed treatment for schizophrenia

Researchers at the University of Miami have developed a family-focused, culturally-informed treatment for schizophrenia (CIT-S). The program is one of the first to incorporate elements of the patient's cultural background as part of therapy.

11 Nov 2014

HLD-200 successfully meets primary endpoint in Phase III study

Highland Therapeutics Inc., a pharmaceutical company, today announced that its wholly owned subsidiary, Ironshore Pharmaceuticals & Development, Inc. has reported positive top-line results from its recently completed Phase III study.

11 Nov 2014

Actamax reports positive results from first clinical study of novel sprayable adhesion barrier device

Actamax Surgical Materials LLC, a DSM-DuPont Joint Venture focusing on the development and commercialization of resorbable, biocompatible surgical medical devices, today announced positive safety and efficacy results from the first clinical evaluation of its novel adhesion barrier device.

11 Nov 2014

FDA accepts Amgen's evolocumab BLA for review

Amgen today announced that the U.S. Food and Drug Administration has accepted for review Amgen's Biologics License Application (BLA) for evolocumab for the treatment of high cholesterol.

11 Nov 2014

UW SMPH awarded $70 million grant to continue work on Inner-City Asthma Consortium

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded the University of Wisconsin School of Medicine and Public Health a seven-year, $70 million grant for its continuing work on the Inner-City Asthma Consortium (ICAC) -- a nationwide clinical research network to evaluate and develop promising new immune-based treatments.

11 Nov 2014

MicroMatrices, Advanced Cell Diagnostics sign preferred partnership agreement

MicroMatrices, a service provider specialised in high resolution cell type-specific analysis to characterise toxicological responses in different cell types in tissue, today announced a preferred partnership agreement with Advanced Cell Diagnostics, Inc., a leader in the field of molecular pathology and developer of cell and tissue-based analysis tools.

From Advanced Cell Diagnostics 11 Nov 2014

New drug combination shows promise as effective, safe treatment for rheumatoid arthritis

A new drug combination for rheumatoid arthritis treats the disease just as well as other intensive treatment strategies but with less medication and fewer side effects at a significantly lower cost. Doctoral researcher Diederik De Cock (KU Leuven) describes the strategy in a new study published in Annals of Rheumatic Diseases.

11 Nov 2014

Inovio Pharmaceuticals reports Q3 2014 financial results, provides corporate update

Inovio Pharmaceuticals, Inc. today reported financial results for the quarter ended September 30, 2014.

10 Nov 2014

Resonance Health launches new diagnostic imaging solution for patients with fatty liver disease

ASX listed Resonance Health officially launched an innovative new diagnostic imaging solution for liver patients worldwide at the American Association for the Study of Liver Diseases annual conference in Boston this week.

10 Nov 2014

LSTM receives research grants to develop Experimental Human Pneumococcal Carriage model

Respiratory specialists at Liverpool School Tropical Medicine (LSTM) have been awarded two substantial research grants to further develop and utilise their Experimental Human Pneumococcal Carriage (EHPC) model.

10 Nov 2014

Actimab-A extends overall survival, reduces bone marrow blasts in older AML patients

Interim data from an ongoing Phase I/II trial of Actimab-A, an innovative targeted payload immunotherapy, demonstrated a number of positive findings, including extension of overall survival and significant reductions in bone marrow blasts in older patients with newly diagnosed Acute Myeloid Leukemia (AML).

7 Nov 2014

LSTM awarded research grants to develop Experimental Human Pneumococcal Carriage model

Respiratory specialists at Liverpool School Tropical Medicine have been awarded two substantial research grants to further develop and utilise their Experimental Human Pneumococcal Carriage (EHPC) model.

7 Nov 2014

Cardiome Pharma announces results from Phase 3 clinical study of BRINAVESS

Cardiome Pharma Corp. today announced results from a Phase 3 clinical study conducted with BRINAVESS (vernakalant intravenous, RSD 1235) in the Asia-Pacific (A-P) region.

7 Nov 2014

Researchers synthetize molecules to block virus that causes influenza A

The influenza A virus is a contagious and severe respiratory infection that affects animals but also humans. Researchers from the University of Barcelona have synthetized some molecules which are able to block the virus that causes influenza A and some of the mutations that make it resistant to common drugs.

7 Nov 2014

Obeticholic acid improves liver health in people with nonalcoholic steatohepatitis

An experimental drug aimed at treating a common liver disease showed promising results and potential problems in a multicenter clinical trial funded by the National Institutes of Health. The FLINT study found that people with nonalcoholic steatohepatitis (NASH) who took obeticholic acid (OCA) had improved liver health during that period, including decreased inflammation and fat in the liver and decreased body weight versus people receiving a placebo. OCA was also associated with increases in itching and total cholesterol.

7 Nov 2014

Efficacy News and Research

Bevacizumab–erlotinib combined efficacy may depend on VEGF level

Eye screenings of underserved populations reveal one in five has early stage diabetic retinopathy

Experimental Ebola treatments to be trialled in West Africa next month

Unique immunochemotherapy approach to treating pancreatic cancer

Amedica, Spinal Kinetics sign multi-year OEM agreement for silicon nitride spinal implants

UM researchers develop novel, family-focused, culturally-informed treatment for schizophrenia

HLD-200 successfully meets primary endpoint in Phase III study

Actamax reports positive results from first clinical study of novel sprayable adhesion barrier device

FDA accepts Amgen's evolocumab BLA for review

UW SMPH awarded $70 million grant to continue work on Inner-City Asthma Consortium

MicroMatrices, Advanced Cell Diagnostics sign preferred partnership agreement

New drug combination shows promise as effective, safe treatment for rheumatoid arthritis

Inovio Pharmaceuticals reports Q3 2014 financial results, provides corporate update

Resonance Health launches new diagnostic imaging solution for patients with fatty liver disease

LSTM receives research grants to develop Experimental Human Pneumococcal Carriage model

Actimab-A extends overall survival, reduces bone marrow blasts in older AML patients

LSTM awarded research grants to develop Experimental Human Pneumococcal Carriage model

Cardiome Pharma announces results from Phase 3 clinical study of BRINAVESS

Researchers synthetize molecules to block virus that causes influenza A

Obeticholic acid improves liver health in people with nonalcoholic steatohepatitis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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