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Polyunsaturated fatty acids play key role in embryonic development

One classical question in developmental biology is how different tissue types arise in the correct position of the developing embryo. While one signaling pathway that controls this process has been well described, unexpected findings from a team led by Carnegie's Steven Farber reveal the importance of polyunsaturated fatty acid metabolism in this process. It is published online December 12 in Developmental Cell.

13 Dec 2013

Psychology researchers and practitioners still hold different beliefs about repressed memories

Skepticism about repressed traumatic memories has increased over time, but new research shows that psychology researchers and practitioners still tend to hold different beliefs about whether such memories occur and whether they can be accurately retrieved.

13 Dec 2013

New mutations in the estrogen receptor drive strong drug resistance exhibited by human breast tumors

Human breast tumors transplanted into mice are excellent models of metastatic cancer and are providing insights into how to attack breast cancers that no longer respond to the drugs used to treat them, according to research from Washington University School of Medicine in St. Louis.

13 Dec 2013

Climate change may lead to decline in snail fever

The dangerous parasite Schistosoma mansoni that causes snail fever in humans could become significantly less common in the future a new international study led by researchers from the University of Copenhagen predicts. The results are surprising because they contradict the general assumption that climate change leads to greater geographical spread of diseases. The explanation is that the parasite's host snails stand to lose suitable habitat due to climate change.

13 Dec 2013

Georgia State University creates new research center to advance nanotechnology and biomedicine

The Center for Nano-Optics, a research center whose focus on the science of developing tools and instruments as small as 1,000 times thinner than a human hair could lead to major breakthroughs in technology and biomedicine, has been created at Georgia State University.

13 Dec 2013

New test may help decrease risk of suicidality in patients treated with antidepressants

The new test, based on research carried out at the Max Planck Institute of Psychiatry, should help doctors to decrease the risk of suicidality in patients treated with antidepressants who show certain gene markers. Sundance is completing a new round of funding to extend the initial validation results reported by the Institute. The company plans to launch the test immediately as a laboratory developed test. In addition, clinical studies in support of a U.S. Food and Drug Administration submission for market clearance, CE marking and reimbursement will be initiated. Sundance expects to submit its application to the agencies within 18 months.

13 Dec 2013

Genomic tests help in selecting the most effective therapy for breast cancer

Genomic tests that determine the molecular subtype of a woman's breast cancer provide a more precise prognosis and valuable guidance about the best treatment, according to new research led by Massimo Cristofanilli, M.D, Director of the Jefferson Breast Care Center at the Kimmel Cancer Center (KCC) and Thomas Jefferson University and Hospitals.

13 Dec 2013

Dasatinib+letrozole improves survival for women with hormone receptor-positive, HER2-negative metastatic breast cancer

Adding the drug dasatinib to a standard antihormone therapy, letrozole, doubled the time before disease progressed for women with hormone receptor-positive, HER2-negative metastatic breast cancer, according to results of a phase II clinical trial presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.

13 Dec 2013

Bioethics Commission releases ethical recommendations to manage incidental and secondary findings

Researchers conduct a memory study, scan a participant's brain, and find more than they bargain for: a tumor. What do the researchers owe the participant? What does the participant want to know?

13 Dec 2013

Transport of bacterial substrates through injectisome observed almost in real time

When attacking body cells, bacteria, such as salmonellae or Yersinia (plague pathogens), inject specific bacterial proteins through hollow, syringe-like structures - called injectisomes - into the host cells. These substances reprogram the cells and can thus overcome their defense. From then on, they can infiltrate the cells unhindered in large numbers, and trigger diseases such as typhus, plague, or cholera.

13 Dec 2013

Massachusetts residents have broader health insurance coverage, greater access to primary care

In 2006, Massachusetts was on the same brink that the entire nation is on today: the brink of expanding health insurance to cover far more people than before, through government-driven, market-based reform.

13 Dec 2013

Methodology needed to diagnose quality of life of individual cancer patients or survivors

Due to improved treatments and technologies, more children than ever are surviving cancer. Unfortunately, about 70 percent of these children experience late effects from their disease and treatment 30 years after their cancer diagnosis, which University of Florida Health researchers say significantly impact their quality of life.

13 Dec 2013

Standardized research approaches needed for developing new treatments for neurofibromatosis

As potentially effective new treatments for neurofibromatosis (NF) are developed, standardized research approaches—including outcome measures specific to NF—are needed. The first report from the Response Evaluation in Neurofibromatosis and Schwannomatosis (REiNS) International Collaboration has been published as a supplement to Neurology, the Official Journal of the American Academy of Neurology (AAN).

13 Dec 2013

Health Law Op-Eds: Obama must 'fire some people'; the law's many possible futures; Obamacare 'is a disaster'

Though the site is working vastly better today than it was two months ago, the debut of HealthCare.gov was a genuine disaster. Specifically, it was a management disaster. CMS's information technology department botched its job as systems integrator for HealthCare.gov. CMS management botched the job of recognizing that CMS's IT department was botching its job.

13 Dec 2013

Researchers uncover second rare genetic mutation linked to higher risk of Alzheimer's disease

A research team from The University of Nottingham has helped uncover a second rare genetic mutation which strongly increases the risk of Alzheimer's disease in later life.

13 Dec 2013

Viewpoints: Problems with the 'doc fix;' a lame budget deal; concerns about changes in doctor training

Imagine if a provision in ObamaCare allowed Health and Human Services Secretary Kathleen Sebelius to dictate directly to doctors which services they could and could not provide their patients - what individual tests they could conduct, which treatments they could offer, and medicines they could prescribe.

13 Dec 2013

Researchers discover completely new targets for treatment of blood cancers

A particularly aggressive form of leukemia is the acute lymphoblastic leukemia (ALL). It is especially common among children and very difficult to treat. Researchers from the University of Veterinary Medicine, Vienna have now discovered completely new targets for the treatment of blood cancers.

13 Dec 2013

Sebelius: Enrollment numbers going up and website getting better, but a review will be launched over healthcare.gov launch problems

Just as the November enrollment figures were released, Health and Human Services Secretary Kathleen Sebelius testified Wednesday before the health subcommittee of the House Energy and Commerce Committee where she was again grilled on the difficulties that have plagued the website's launch and other related issues.

13 Dec 2013

Repeated blows to head in contact sports may cause changes in brain's white matter

Repeated blows to the head during a season of contact sports may cause changes in the brain's white matter and affect cognitive abilities even if none of the impacts resulted in a concussion, according to a study published today in the journal Neurology.

13 Dec 2013

Groundbreaking UVA research receives $3.3M NIH grant to increase lungs for transplantation

Groundbreaking research at the University of Virginia School of Medicine that aims to dramatically increase the number of lungs that can be used for transplant has received a $3.3 million grant from the National Institutes of Health.

13 Dec 2013

Research News and Research

Polyunsaturated fatty acids play key role in embryonic development

Psychology researchers and practitioners still hold different beliefs about repressed memories

New mutations in the estrogen receptor drive strong drug resistance exhibited by human breast tumors

Climate change may lead to decline in snail fever

Georgia State University creates new research center to advance nanotechnology and biomedicine

New test may help decrease risk of suicidality in patients treated with antidepressants

Genomic tests help in selecting the most effective therapy for breast cancer

Dasatinib+letrozole improves survival for women with hormone receptor-positive, HER2-negative metastatic breast cancer

Bioethics Commission releases ethical recommendations to manage incidental and secondary findings

Transport of bacterial substrates through injectisome observed almost in real time

Massachusetts residents have broader health insurance coverage, greater access to primary care

Methodology needed to diagnose quality of life of individual cancer patients or survivors

Standardized research approaches needed for developing new treatments for neurofibromatosis

Health Law Op-Eds: Obama must 'fire some people'; the law's many possible futures; Obamacare 'is a disaster'

Researchers uncover second rare genetic mutation linked to higher risk of Alzheimer's disease

Viewpoints: Problems with the 'doc fix;' a lame budget deal; concerns about changes in doctor training

Researchers discover completely new targets for treatment of blood cancers

Sebelius: Enrollment numbers going up and website getting better, but a review will be launched over healthcare.gov launch problems

Repeated blows to head in contact sports may cause changes in brain's white matter

Groundbreaking UVA research receives $3.3M NIH grant to increase lungs for transplantation

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