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Study uncovers novel mechanism by which glioblastoma evades targeted therapies

A Ludwig Cancer Research study has uncovered an entirely novel mechanism by which glioblastoma, the most common kind of brain cancer, evades targeted therapies. Published in the current issue of the journal Science, the paper describes how GBM tumor cells essentially hide the signaling molecule targeted by such therapies, adding a layer of complexity to current models of drug resistance in cancer.

6 Dec 2013

Low vitamin D levels: Not a cause but a consequence of ill health

A comprehensive review of the evidence suggests that low vitamin D levels are not a cause but a consequence of ill health, casting strong doubt on the value of vitamin D supplements to protect against acute and chronic disorders such as cancer, cardiovascular disease, diabetes, Parkinson’s disease, and even death.

6 Dec 2013

Scientists to deliver lecture on innovations in chemistry at ACS meeting

One scientist is developing breakthrough electronic sutures and medical implants that dissolve when their jobs are done. Another is a pioneer in the field of energy conversion that could lead to development of high-performance solar cells and new types of electronic devices that could integrate into the body.

6 Dec 2013

Women with moderate to severe menstrual cramps may find relief in erectile dysfunction drugs

Women with moderate to severe menstrual cramps may find relief in a class of erectile dysfunction drugs, according to a team of researchers led by Penn State College of Medicines Richard Legro.

6 Dec 2013

New project aims to reduce animal testing for drug development

Researchers at the University of East Anglia are launching a new project to develop methods which could one-day decrease the use of rats and mice in pharmaceutical testing.

6 Dec 2013

Eli Lilly reports edivoxetine Phase III program did not meet primary endpoint for major depressive disorder

Eli Lilly and Company (NYSE: LLY) announced today that results from three studies of edivoxetine did not meet the primary study objective of superior efficacy in depression after eight weeks of treatment.

6 Dec 2013

Eisai reports new data analyses on FYCOMPA (Perampanel) at AES meeting

Today, Eisai Inc. announced that 16 abstracts highlighting new data analyses on FYCOMPA (perampanel) will be presented at the 67th annual American Epilepsy Society (AES) meeting, taking place in Washington, D.C. from December 6 – 10.

6 Dec 2013

Edison Investment Research's report examines long-term investment case for Bavarian Nordic

Edison Investment Research's report, An intriguing PROSPECT, examines the long-term investment case for Bavarian Nordic, which rests on key value driver Prostvac, its Phase III prostate cancer vaccine.

6 Dec 2013

Scientists test affected human nerve cells to foretell efficacy of Alzheimer drugs

Why do certain Alzheimer medications work in animal models but not in clinical trials in humans? A research team from the University of Bonn and the biomedical enterprise LIFE & BRAIN GmbH has been able to show that results of established test methods with animal models and cell lines used up until now can hardly be translated to the processes in the human brain. Drug testing should therefore be conducted with human nerve cells, conclude the scientists.

6 Dec 2013

Central analgesic mechanism of acupuncture for treating migraine remains poorly understood

The central analgesic mechanism of acupuncture for migraine remains poorly understood. Acupuncture has been shown to become a recommended treatment for migraine sufferers.

6 Dec 2013

Biocartis, VIB partner to develop novel MSI biomarkers for colorectal cancer

Today Biocartis and VIB announced their exclusive license agreement on a novel panel of microsatellite instability biomarkers for several cancers, in particular colorectal cancer.

From Biocartis 6 Dec 2013

Study identifies specific DCPR syndromes that could affect obesity

A study published in the current issue of Psychotherapy and Psychosomatics has applied diagnostic criteria for psychosomatic syndromes to a sample of patients with morbid obesity.

6 Dec 2013

Innovative DNA engineering technique discovers potential functions hidden within bacterial genomes

A group of University of Illinois researchers, led by Centennial Chair Professor of the Department of Chemical and Biomolecular Engineering Huimin Zhao, has demonstrated the use of an innovative DNA engineering technique to discover potentially valuable functions hidden within bacterial genomes.

6 Dec 2013

State highlights: S.C. Medicaid director touts lower spending; La. targets docs who steer patients into some managed care plans; Texas set to boost Medicaid payments

South Carolina's Medicaid director says his agency is on track to spend about $250 million less this fiscal year than allotted in the state budget. Director Tony Keck told a Senate panel on Wednesday the Department of Health and Human Services is projected to spend $6.2 billion in state and federal money (Adcox, 12/4).

6 Dec 2013

Understanding biochemical mechanisms associated with memory formation

A discovery by a research team led by Dr. Ryohei Yasuda at the Max Planck Florida Institute for Neuroscience has significantly advanced basic understanding of biochemical mechanisms associated with how memories are formed.

6 Dec 2013

Powder, crack cocaine use varies and overlaps among high school seniors

The use of crack and powder cocaine both varies and overlaps among high school seniors, researchers at New York University and NYU Langone Medical Center have found. Their findings, which appear in the American Journal of Drug and Alcohol Abuse, point to the need to take into account both common and different at-risk factors in developing programming and messaging to stem cocaine use.

6 Dec 2013

Nation's largest freight carriers to offer health benefits to same-sex spouses

A day after being sued by legally married, gay engineers, the nation's largest freight rail carriers announced they will provide health care benefits to the same-sex spouses of their employees.

6 Dec 2013

Researchers discover biological mechanism that allows brain tumor cells to escape from drugs

Researchers from UCLA's Jonsson Comprehensive Cancer Center have discovered a biological mechanism that allows brain tumor cells to escape from the drugs designed to target them, resulting in drug resistance. The study was published in the December 5, 2013 online issue of Science.

6 Dec 2013

Scientists receive 2013 Louisa Gross Horwitz Prize for advancements in field of neuroscience

For discoveries about how the brain calculates and remembers where it is—which could be part of the foundation of memory—Columbia University will award the 2013 Louisa Gross Horwitz Prize to Edvard I. Moser, PhD, and May-Britt Moser, PhD, of the Norwegian University of Science and Technology in Norway, and John Michael O'Keefe, PhD, of University College London in the UK.

6 Dec 2013

Viewpoints: Coping with physician shortage; 'righteous' hobby lobby cause; enrolling millennials

In just over a decade the United States will need 130,000 more doctors than medical schools are producing. So says the Association of American Medical Colleges, which warns of a doctor shortage that will drive up wait times, shorten office visits and make it harder for Americans to access the care they need (Scott Gottlieb and Ezekiel J. Emanuel, 12/4).

6 Dec 2013

Research News and Research

Study uncovers novel mechanism by which glioblastoma evades targeted therapies

Low vitamin D levels: Not a cause but a consequence of ill health

Scientists to deliver lecture on innovations in chemistry at ACS meeting

Women with moderate to severe menstrual cramps may find relief in erectile dysfunction drugs

New project aims to reduce animal testing for drug development

Eli Lilly reports edivoxetine Phase III program did not meet primary endpoint for major depressive disorder

Eisai reports new data analyses on FYCOMPA (Perampanel) at AES meeting

Edison Investment Research's report examines long-term investment case for Bavarian Nordic

Scientists test affected human nerve cells to foretell efficacy of Alzheimer drugs

Central analgesic mechanism of acupuncture for treating migraine remains poorly understood

Biocartis, VIB partner to develop novel MSI biomarkers for colorectal cancer

Study identifies specific DCPR syndromes that could affect obesity

Innovative DNA engineering technique discovers potential functions hidden within bacterial genomes

State highlights: S.C. Medicaid director touts lower spending; La. targets docs who steer patients into some managed care plans; Texas set to boost Medicaid payments

Understanding biochemical mechanisms associated with memory formation

Powder, crack cocaine use varies and overlaps among high school seniors

Nation's largest freight carriers to offer health benefits to same-sex spouses

Researchers discover biological mechanism that allows brain tumor cells to escape from drugs

Scientists receive 2013 Louisa Gross Horwitz Prize for advancements in field of neuroscience

Viewpoints: Coping with physician shortage; 'righteous' hobby lobby cause; enrolling millennials

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