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ERYTECH partners with Queen’s University to advance its product candidate for treating arginase-1 deficiency

ERYTECH Pharma, a French clinical-stage biopharmaceutical company developing innovative therapies for rare forms of cancer and orphan diseases, today announced that it has entered into a research collaboration with Queen's University in Canada to advance the preclinical development of ERYTECH's eryminase program specifically for the treatment of arginase-1 deficiency, a rare and severe metabolic disorder related to arginine metabolism.

12 Jul 2017

Intestinal viruses may affect person's chance of developing Type 1 diabetes

Doctors can't predict who will develop Type 1 diabetes, a chronic autoimmune disease in which one's own immune system destroys the cells needed to control blood-sugar levels, requiring daily insulin injections and continual monitoring.

11 Jul 2017

Sialic acid found in animals protects farm children from asthma

It is a known fact that microbes on farms protect children from asthma and allergies. But even non-microbial molecules can have a protective effect: Immunologists from the University of Zurich have shown that a sialic acid found in farm animals is effective against inflammation of lung tissue.

6 Jul 2017

Binge drinking likely to contribute to development of compulsive alcohol consumption

Prior research suggests that binge drinking may increase people's risk of developing alcohol use disorders (AUDs), especially adolescents and young adults.

6 Jul 2017

Scientists discover link between sugar metabolism and peroxisomal biogenesis disorders

Meeting a young patient with Zellweger syndrome, a rare, life-threatening genetic disease, started a scientific investigation that culminated with an unexpected discovery.

23 Jun 2017

Prenatal exposure to pain-relieving drug can impair development of male behavior

Paracetamol is popular for relieving pain. But if you are pregnant, you should think twice before popping these pills according to the researchers in a new study.

22 Jun 2017

Microscopic fungus exacerbates Crohn's disease symptoms, mice study shows

A microscopic fungus called Candida tropicalis triggered gut inflammation and exacerbated symptoms of Crohn's disease, in a recent study conducted at Case Western Reserve University School of Medicine.

22 Jun 2017

Temple researchers identify protective effects of extra-virgin olive oil against Alzheimer's disease

The Mediterranean diet, rich in plant-based foods, is associated with a variety of health benefits, including a lower incidence of dementia.

21 Jun 2017

Animal model of Gulf War illness hints at possible ways to mitigate symptoms

When hundreds of thousands of American troops deployed to the Persian Gulf in 1990 and 1991 in what is now called the First Gulf War, they were exposed to a variety of chemicals.

20 Jun 2017

Cells key to blood vessel formation can also produce tumors and enable their spread

While it's widely held that tumors can produce blood vessels to support their growth, scientists now have evidence that cells key to blood vessel formation can also produce tumors and enable their spread.

20 Jun 2017

Scientists design bioactive nanomaterial that excels at stimulating bone regeneration

There hasn't been a gold standard for how orthopaedic spine surgeons promote new bone growth in patients, but now Northwestern University scientists have designed a bioactive nanomaterial that is so good at stimulating bone regeneration it could become the method surgeons prefer.

19 Jun 2017

Long-distance brain connections can target, stimulate discrete pools of stem cells

Stem cells persist in the adult mammalian brain and generate new neurons throughout life. A research group at the Biozentrum of the University of Basel reports in the current issue of "Science" that long-distance brain connections can target discrete pools of stem cells in their niche and stimulate them to divide and produce specific subtypes of olfactory bulb neurons

16 Jun 2017

SLU scientists discover nuclear receptor that appears to play key role in muscle regeneration

Saint Louis University researchers report in Molecular Metabolism new findings that the nuclear receptor REV-ERB appears to play a key role in muscle regeneration, suggesting the receptor may be a good target for new drugs to treat a variety of muscle disorders and injuries.

14 Jun 2017

New research uncovers subcellular-level changes in the brain after concussion

New research has uncovered details about subcellular-level changes in the brain after concussion that could one day lead to improved treatment.

14 Jun 2017

Research reveals link between POMC neurons and release of insulin by the pancreas

The brain is key in the regulation of appetite, body weight and metabolism. Specifically, there is a small group of hypothalamus neurons, called POMC, that detect and integrate signals that inform on the energy state of the organism and activate the appropriate physiological responses.

8 Jun 2017

SLU scientist discovers cause and potential solution for cancer-related bone pain

In a paper published in the journal Pain, Saint Louis University researcher Daniela Salvemini, Ph.D., reports discovering a key molecular pathway that drives cancer-related bone pain while providing a potential solution with a drug that already is on the market.

8 Jun 2017

Animal Model News and Research

ERYTECH partners with Queen’s University to advance its product candidate for treating arginase-1 deficiency

Intestinal viruses may affect person's chance of developing Type 1 diabetes

Sialic acid found in animals protects farm children from asthma

Binge drinking likely to contribute to development of compulsive alcohol consumption

Scientists discover link between sugar metabolism and peroxisomal biogenesis disorders

Prenatal exposure to pain-relieving drug can impair development of male behavior

Microscopic fungus exacerbates Crohn's disease symptoms, mice study shows

Temple researchers identify protective effects of extra-virgin olive oil against Alzheimer's disease

Animal model of Gulf War illness hints at possible ways to mitigate symptoms

Cells key to blood vessel formation can also produce tumors and enable their spread

Scientists design bioactive nanomaterial that excels at stimulating bone regeneration

Long-distance brain connections can target, stimulate discrete pools of stem cells

SLU scientists discover nuclear receptor that appears to play key role in muscle regeneration

New research uncovers subcellular-level changes in the brain after concussion

Research reveals link between POMC neurons and release of insulin by the pancreas

SLU scientist discovers cause and potential solution for cancer-related bone pain

Bern researchers find new way to influence the endocannabinoid system

Follistatin plays key role in embryo implantation

Mouse model could improve understanding of human brown fat’s role in metabolic processes

Assessing safety and toxicity of bioactives could be key to establishing tolerable upper intake levels

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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