Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

APOE ε4 predicts risk of future depression

One of the most powerful predictors in neuropsychiatry is the epsilon 4 (ε4) allele of the apolipoprotein gene (APOE).

3 Nov 2015

Federal food policy changes boost healthful food options at smaller urban corner stores

Federal food policy changes led to increased availability of healthy foods at smaller urban corner stores in Baltimore, new Johns Hopkins Bloomberg School of Public Health research suggests. Increases in healthy food were greatest in corner stores and in neighborhoods with a majority of black residents.

3 Nov 2015

Diet diversity associated with lower diet quality and worse metabolic health

Diet diversity, as defined by less similarity among the foods people eat, may be linked to lower diet quality and worse metabolic health, according to researchers at The University of Texas Health Science Center at Houston and the Friedman School of Nutrition Science and Policy at Tufts University.

31 Oct 2015

Liposomal sizing and the Coulter principle: an interview with Professor Melvin E. Klegerman

For about the last 25 years, the cardiology group here have been developing a platform technology for both the diagnosis and treatment of atherosclerosis.

From Beckman Coulter Life Sciences - Particle Counting and Characterization 28 Oct 2015

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

Four tiny segments of RNA appear to play critical roles in controlling cholesterol and triglyceride metabolism. In their report receiving advance online publication in Nature Medicine, a Massachusetts General Hospital-based research team describes finding how these microRNAs could reduce the expression of proteins playing key roles in the generation of beneficial HDL cholesterol, the disposal of artery-clogging LDL cholesterol, control of triglyceride levels and other risk factors of cardiovascular disease.

27 Oct 2015

Patrolling monocytes may play anti-cancer role in the lung

One goal of immunotherapy is to rally a patient's often over-burdened immune cells to effectively attack a tumor. Among foot soldiers on the immune front line is a subpopulation of white blood cells called "patrolling monocytes," whose job is to cruise the bloodstream, cart off cellular debris, and block invasion of a less benign population of inflammatory cells.

23 Oct 2015

CV risk assessment essential for CML TKI trial design

The risk and impact of cardiovascular adverse events in long-term users of tyrosine kinase inhibitors for chronic myeloid leukaemia is highlighted in a review published in the Journal of Clinical Oncology.

22 Oct 2015

Current approach to blood pressure treatment can't restore cardiovascular risk to ideal levels, study suggests

Treating out-of-control blood pressure with antihypertensive medication can greatly reduce your risk for heart attack, stroke and heart failure, but the current approach to treatment can't undo all of the previous damage or restore cardiovascular disease risk to ideal levels, a new Northwestern Medicine study suggests.

22 Oct 2015

Low levels of stem cell factor associated with increased risk of cardiovascular disease

New research indicates that low levels of a growth factor called stem cell factor (SCF)--which is thought to be important for blood vessel repair--are linked with an increased risk of cardiovascular disease.

20 Oct 2015

New MRI study shows heart ages differently in men and women

A federally funded analysis of MRI scans of the aging hearts of nearly 3,000 adults shows significant differences in the way male and female hearts change over time.

20 Oct 2015

NAM announces election of three new members from UC San Diego School of Medicine

The National Academy of Medicine announced today the election of three new members from University of California, San Diego School of Medicine: Napoleone Ferrara, MD; Christopher K. Glass, MD, PhD; and Roberto Malinow, MD, PhD. Election to NAM is considered among the highest honors in the fields of health and medicine.

20 Oct 2015

Infections experienced in childhood may lead to premature ACS or heart attacks

"Cardiovascular disease (CVD) is the number one killer worldwide, including in Indonesia where it accounts for 31.9% of all deaths," said Dr Qanitha. "CVD risk factors are rising rapidly in South-East Asia, particularly in young people. Most Indonesian CVD patients are under 56 years old and still economically productive. This very young CVD onset raises the question of whether local circumstances may play a role."

19 Oct 2015

New tool may help identify high risk atherosclerotic plaques

Researchers have developed and validated a new tool to help identify unstable or high risk atherosclerotic plaques--inflamed fatty deposits in the artery wall and a main contributor to cardiovascular disease (CVD). This breakthrough may lead to better identifying which plaques are considered at the highest risk for rupturing and causing a heart attack or stroke.

14 Oct 2015

Cranberry juice consumption may protect against cardiovascular disease

Results from a new study presented at the Cranberry Health Research Conference preceding the annual Berry Health Benefits Symposium 2015 in Madison, WI, revealed that cranberry juice consumption may play a role in protecting against cardiovascular disease.

12 Oct 2015

HDL not so good in protecting women against atherosclerosis, study shows

What has previously been known as good cholesterol--high density lipoprotein (HDL)--has now been shown to be not so good in protecting women against atherosclerosis while they are transitioning through menopause. That's according to a new study from the University of Pittsburgh Graduate School of Public Health that was presented last week at the annual meeting of The North American Menopause Society in Las Vegas.

9 Oct 2015

Repatha (evolocumab) injection gets FDA approval for high cholesterol

The U.S. Food and Drug Administration today approved Repatha (evolocumab) injection for some patients who are unable to get their low-density lipoprotein (LDL) cholesterol under control with current treatment options.

9 Oct 2015

FDA grants 12-year exclusivity to RUCONEST (C1 esterase inhibitor [recombinant])

Salix Pharmaceuticals and Pharming Group NV announced today that the U.S. Food and Drug Administration has granted 12 years of exclusivity to RUCONEST (C1 esterase inhibitor [recombinant]) 50 IU/kg.

8 Oct 2015

New approach helps create virtual models for treating abdominal aortic aneurysms

Virtual models can be created in the angiography room thanks to an approach developed by researchers at the University of Montreal Hospital Research Centre and the university's departments of radiology, radiation oncology, and nuclear medicine. The latest advances were presented by Dr. Gilles Soulez at the Cardiovascular and Interventional Radiology Society of Europe conference on September 27, 2015.

8 Oct 2015

UT Southwestern Medical Center geneticist named 2015 recipient of Pearl Meister Greengard Prize

UT Southwestern Medical Center geneticist Dr. Helen Hobbs is the 2015 recipient of the prestigious Pearl Meister Greengard Prize. The prize recognizes Dr. Hobbs' research, which advances understanding of heart disease and other complex disorders.

29 Sep 2015

Inflammatory response could be key link between dietary fats and obesity-related diseases

An enhanced inflammatory response could be the key link between high saturated fat intake - a recognized risk factor for obesity-related disorders - and the development of diseases like type 2 diabetes and atherosclerosis.

26 Sep 2015

Atherosclerosis News and Research

Further Reading

APOE ε4 predicts risk of future depression

Federal food policy changes boost healthful food options at smaller urban corner stores

Diet diversity associated with lower diet quality and worse metabolic health

Liposomal sizing and the Coulter principle: an interview with Professor Melvin E. Klegerman

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

Patrolling monocytes may play anti-cancer role in the lung

CV risk assessment essential for CML TKI trial design

Current approach to blood pressure treatment can't restore cardiovascular risk to ideal levels, study suggests

Low levels of stem cell factor associated with increased risk of cardiovascular disease

New MRI study shows heart ages differently in men and women

NAM announces election of three new members from UC San Diego School of Medicine

Infections experienced in childhood may lead to premature ACS or heart attacks

New tool may help identify high risk atherosclerotic plaques

Cranberry juice consumption may protect against cardiovascular disease

HDL not so good in protecting women against atherosclerosis, study shows

Repatha (evolocumab) injection gets FDA approval for high cholesterol

FDA grants 12-year exclusivity to RUCONEST (C1 esterase inhibitor [recombinant])

New approach helps create virtual models for treating abdominal aortic aneurysms

UT Southwestern Medical Center geneticist named 2015 recipient of Pearl Meister Greengard Prize

Inflammatory response could be key link between dietary fats and obesity-related diseases

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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