Electron Microscopy News and Research

RSS

Researchers uncover structure of embryo-protecting protein

Revelations about a protein expressed in fetal cells could provide novel insights into its function and future immunosuppressive therapies.

10 May 2017

Detailed images reveal how regulatory proteins affect function of brain receptors

Scientists at Columbia University have obtained the first detailed images of interactions between the AMPA receptor and molecules that regulate chemical signaling in the brain.

3 May 2017

New chiral molecular sieves may lead to production of better drugs

An international team of researchers, led by Mark E. Davis at Caltech, has succeeded in making the first chiral molecular sieves. This discovery opens new areas of investigation in both chemistry and biology, and has broad implications for pharmaceutical companies and other specialized chemical manufacturers.

2 May 2017

TSRI scientists reveal important role of genetics in brain circuits

Scientists at The Scripps Research Institute in La Jolla have revealed new clues to the wiring of the brain. A team led by Associate Professor Anton Maximov found that neurons in brain regions that store memory can form networks in the absence of synaptic activity.

19 Apr 2017

Atomic resolution structure of key molecule may contribute to drug discovery for devastating conditions

Culminating a nearly 10 year effort, researchers have determined the atomic resolution structure of a key molecule that translates signals from a cell's local environment into a language that the cell can understand and use.

18 Apr 2017

MIT researchers develop new technique to make high-resolution images of tissues

MIT researchers have developed a way to make extremely high-resolution images of tissue samples, at a fraction of the cost of other techniques that offer similar resolution.

17 Apr 2017

New research sheds light on movement of white blood cells to sites of infection

One of the mysteries of the living body is the movement of cells - not just in the blood, but through cellular and other barriers.

10 Apr 2017

Researchers observe crystallization on molecular level for the first time

Crystallization is a very basic chemical process: School children can witness it with their own eyes. But scientists had not, until now, been able to observe this process on the molecular level - that is, the instant in which molecules overcome their tendencies to float individually in a liquid solution and take their place in the rigid lattice of a solid crystal structure.

10 Apr 2017

Using nanodiamonds to see smaller

Many of the most fundamental, life governing biological processes take place at size and time scales that remain invisible with current imaging technologies. Understanding how the molecules that underlie these processes move, interact and change could pave the way for new treatments, cures and the development of novel drug therapies.

7 Apr 2017

Study reveals high-resolution view of Zika viral life cycle within infected cells

New research reveals a high-resolution view of the Zika viral life cycle within infected cells and shows dramatic changes in the cell's architecture throughout the infection process. This novel perspective may lead to the development of new vaccines and treatments.

30 Mar 2017

TSRI researchers reveal how viruses incapacitate bacterial defense system

Picture bacteria and viruses locked in an arms race. For many bacteria, one line of defense against viral infection is a sophisticated RNA-guided "immune system" called CRISPR-Cas.

28 Mar 2017

Scientists achieve closest view of working nerve synapses using custom-built microscope

The brain hosts an extraordinarily complex network of interconnected nerve cells that are constantly exchanging electrical and chemical signals at speeds difficult to comprehend.

24 Mar 2017

Scientists map three-dimensional structure of protein that causes cystic fibrosis

Scientists at The Rockefeller University have mapped the three-dimensional structure for one of the more notorious disease-causing molecules in the human body: the protein responsible for the genetic disorder cystic fibrosis. And it looks fishy.

23 Mar 2017

Researchers uncover major clue to how mucus becomes abnormal in CF airways

People with cystic fibrosis (CF) suffer repeated lung infections because their airway mucus is too thick and sticky to keep bacteria, viruses, and other pathogens from causing chronic infection.

23 Mar 2017

High-resolution images of protein complex performing first step in genome-replication dance captured

It's a good thing we don't have to think about putting all the necessary pieces in place when one of our trillions of cells needs to duplicate its DNA and then divide to produce identical daughter cells.

17 Mar 2017

Study shows how immune cells drive heart damage in mice

A new study in mice reveals that eosinophils, a type of disease-fighting white blood cell, appear to be at least partly responsible for the progression of heart muscle inflammation to heart failure in mice.

16 Mar 2017

Pittcon 2017: reflections from the floor

Pittcon 2017 commenced with a fascinating talk by world-renowned optogenetics expert Dr. Karl Deisseroth, D.H. Chen Professor of Bioengineering, Psychiatry and Behavioral Sciences, Stanford University and Investigator of the Howard Hughes Medical Institute.

From Pittcon 9 Mar 2017

Sheffield researchers use JPK's NanoWizard AFM systems to study soft matter, biological systems at molecular scale

JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, works closely with users at the University of Sheffield where their NanoWizard AFM systems are being used to further understand soft matter and biological systems at the molecular scale in the Hobbs SPM Group in the Department of Physics.

From Bruker BioAFM 9 Mar 2017

NovAliX's new laboratory to use cryo-TEM for facilitating small molecule and biologic drug discovery

A new contract research laboratory operated by France-based NovAliX will provide pharmaceutical companies with access to high-resolution cryo-transmission electron microscopy (cryo-TEM) by Thermo Fisher Scientific for facilitating small molecule and biologic drug discovery.

3 Mar 2017

Scientists discover how genetic mutation disarms tumor-suppressing BRCA1 proteins in breast cancer

Of the more than 3 million people with breast cancer in the United Stated, about 10 percent carry an inherited mutation in their BRCA1 gene. In health, the gene is responsible for suppressing tumors. In disease, the gene goes terribly awry.

28 Feb 2017