in vivo News and Research

RSS

Powerful two-photon microscopy for imaging fast biological processes

Two-photon microscopy (TPM) has revolutionized the field of biology by enabling researchers to observe complex biological processes in living tissues at high resolution.

4 May 2023

Revving up COVID mRNA vaccines: Algorithm generates 128-fold increase in antibodies

Research paper proposes a new method for predicting highly expressed genes based on codon usage bias and minimum free energy of mRNA secondary structures. The method involves constructing a stochastic grammar that generates sequences with high CAI and low MFE, and testing it on two mRNA vaccines.

3 May 2023

Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

In a recent study published in the journal Cell Stem Cell, researchers hypothesized that pacemaker-like activity of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) resulted in engraftment arrhythmias (EAs), which hampers the clinical use of cell-based therapy using hPSC-CMs for treatment of myocardial infarction (MI).

2 May 2023

Does carrot-derived rhamnogalacturonan I positively impact gut microbiota composition and function?

Researchers assessed how carrot-derived rhamnogalacturonan I (cRG-I) impacted the human gut microbiota.

28 Apr 2023

Developing Next-Generation Nanomaterials for Medical Applications

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to Dr. Chad Merkin, Director of the International Institute for Nanotechnology, about his work developing next-generation nanomaterials for medical applications.

From Pittcon 27 Apr 2023

Print your own vaccine: automatic printing of microneedle patch COVID-19 mRNA vaccines

Researchers reported on the automatic printing of microneedle patch SARS-CoV-2 mRNA vaccines.

26 Apr 2023

Shedding light on diabetes: Vitamin D's crucial role in insulin regulation and disease prevention

Research discusses the role of vitamin D in both type 1 and type 2 diabetes pathogenesis. It summarizes the molecular mechanisms of vitamin D in insulin secretion, insulin sensitivity, and immunity, as well as the observational and interventional human studies investigating the use of vitamin D as a treatment for diabetes.

25 Apr 2023

Study establishes a new method for examining relationships between neuron type and function

Investigators at Cedars-Sinai have created computer-generated models to bridge the gap between "test tube" data about neurons and the function of those cells in the living brain.

25 Apr 2023

Is there an association between the consumption of ultra-processed food and adverse microbiota-gut-brain axis implications?

Researchers reviewed the impact of ultra-processed foods (UPFs) on the microbiota-gut-brain axis.

25 Apr 2023

Understanding how consumption of beef vs. plant-based burgers alters the lipemic response and gut microbiota

Researchers reviewed the differences in the digestive process between beef and plant-based burgers from ingestion to excretion.

25 Apr 2023

Bee venom nanoparticles: Buzzworthy breakthrough in battling antibiotic-resistant bacteria

Study aimed to test the antibacterial and cytotoxic effects of bee venom-loaded chitosan nanoparticles (BV-loaded CS-NPs) against Staphylococcus aureus. The results showed that BV-loaded CS-NPs had enhanced antibacterial activity and minimal cytotoxicity, making it a promising antibiotic alternative.

24 Apr 2023

Deciphering immunological imprinting in the context of COVID-19

In a recent article published in the journal Immunity, researchers explained the concept of immunological imprinting and its underlying principles. They also discussed its potential role in the context of coronavirus disease 2019 (COVID-19) vaccines.

24 Apr 2023

Researchers develop a backpack-based myeloid cell therapy for MS patients

Multiple sclerosis (MS) is a devastating autoimmune disease that destroys the protective myelin covering around nerves, disrupting communication between the brain and body, and causing patients' ability to move and function to progressively decline.

21 Apr 2023

Study identifies various biomarkers of moderate alcohol intake and alcoholic beverages

Researchers determined and validated ethanol intake biomarkers that can be used to accurately assess alcohol intake.

21 Apr 2023

Brain's glucose metabolism: Key to unlocking new therapies for Alzheimer's and Parkinson's

...

20 Apr 2023

Omicron spike N679K mutation acts as a loss-of-function mutation attenuating SARS-CoV-2 in vitro & in vivo

Researchers explored the impact of a loss-of-function mutation in the SARS-CoV-2 Omicron variants on the expression of the spike protein.

20 Apr 2023

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Researchers explored increasing replicative fitness of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants

20 Apr 2023

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Research explains how the SARS-CoV-2 virus spreads efficiently by directly infecting neighboring cells through a process called cell-to-cell transmission. The virus uses a protein called occludin (OCLN) to enter the cells and causes syncytium formation, which leads to viral spread.

20 Apr 2023

Researchers compare the action of natural and therapeutic opioids

The human body naturally produces opioid-like substances, such as endorphins, which block the perception of pain and increase the feeling of well-being.

19 Apr 2023

Unlocking the potential of RNA lipid nanoparticles to revolutionize cancer treatment

This paper discusses the use of RNA lipid nanoparticles for cancer immunotherapy, which has shown promising results in clinical use. However, only a small percentage of patients respond to existing immunotherapies, and the paper explores opportunities for improvement.

18 Apr 2023

in vivo News and Research

Powerful two-photon microscopy for imaging fast biological processes

Revving up COVID mRNA vaccines: Algorithm generates 128-fold increase in antibodies

Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

Does carrot-derived rhamnogalacturonan I positively impact gut microbiota composition and function?

Developing Next-Generation Nanomaterials for Medical Applications

Print your own vaccine: automatic printing of microneedle patch COVID-19 mRNA vaccines

Shedding light on diabetes: Vitamin D's crucial role in insulin regulation and disease prevention

Study establishes a new method for examining relationships between neuron type and function

Is there an association between the consumption of ultra-processed food and adverse microbiota-gut-brain axis implications?

Understanding how consumption of beef vs. plant-based burgers alters the lipemic response and gut microbiota

Bee venom nanoparticles: Buzzworthy breakthrough in battling antibiotic-resistant bacteria

Deciphering immunological imprinting in the context of COVID-19

Researchers develop a backpack-based myeloid cell therapy for MS patients

Study identifies various biomarkers of moderate alcohol intake and alcoholic beverages

Brain's glucose metabolism: Key to unlocking new therapies for Alzheimer's and Parkinson's

Omicron spike N679K mutation acts as a loss-of-function mutation attenuating SARS-CoV-2 in vitro & in vivo

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Researchers compare the action of natural and therapeutic opioids

Unlocking the potential of RNA lipid nanoparticles to revolutionize cancer treatment

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News