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Immunologists propose possible molecular mechanism for the deadly respiratory syndrome

Research into how the SARS-CoV-2 virus induces death is suggesting potential treatments for its most destructive complications.

20 May 2020

New technique determines lipid composition in a brain region

Researchers at the Beckman Institute at the University of Illinois at Urbana-Champaign have developed a new technique that can determine the specific molecular form, location, and the number of lipids in samples of rat brain tissue.

20 May 2020

New study may eliminate dangerous side effects of drugs used for treating various conditions

Psychedelics such as LSD and magic mushrooms have proven highly effective in treating depression and post-traumatic stress disorders, but medical use of these drugs is limited by the hallucinations they cause.

20 May 2020

New drug treatment can reduce risk of death from COVID-19 infection

Researchers in the Ludwig Center at the Johns Hopkins Kimmel Cancer Center report they have identified a drug treatment that could--if given early enough--potentially reduce the risk of death from the most serious complication of Coronavirus disease 2019 (COVID-19), also known as SARS-CoV-2 infection.

20 May 2020

MU researchers examine how menopause can impact cognitive function

Characterized by a buildup of amyloid plaques in the brain, Alzheimer's is an irreversible disease that leads to memory loss and a decrease in cognitive function.

19 May 2020

Understanding why pancreatic ductal adenocarcinoma is so aggressive

Pancreatic ductal adenocarcinoma (PDA) is a deadly cancer, killing patients within a year. CSHL Professor Christopher Vakoc and his former postdoc Timothy Somerville discovered how pancreatic cells lose their identity, acquire a deadly new identity, and recruit nearby cells to help them grow, promote inflammation, and invade nearby tissues.

19 May 2020

DZD researchers discover additional genetic cause for non-alcoholic fatty liver disease

In Germany about 18 million people suffer from non-alcoholic fatty liver. The causes of this disease are manifold and include environmental as well as genetic factors.

19 May 2020

Phase IIB clinical trial initiated for treating hepatitis B-associated liver cancer

The first patients have been dosed in a multi-regional Phase IIB randomized, placebo-controlled clinical trial for the treatment of hepatitis B-associated liver cancer.

19 May 2020

Hop supplements used by menopausal women are not likely to cause drug interactions

Hop-based dietary supplements that many women use to ease the night sweats and hot flashes commonly reported during menopause aren't likely to cause drug interactions, new research from Oregon State University's Linus Pauling Institute and College of Pharmacy shows.

19 May 2020

New technique produces pure therapeutic drugs without the associated side effects

Scientists from Hong Kong Baptist University (HKBU) have developed a novel technique that can produce pure therapeutic drugs without the associated side effects.

19 May 2020

SWOG scientists to deliver online presentations at ASCO20 Virtual Scientific Program

Researchers from SWOG, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health, will make 31 presentations as part of the ASCO20 Virtual Scientific Program, the online annual meeting of the American Society of Clinical Oncology (ASCO), which runs May 29-31.

19 May 2020

Study highlights need to focus on medications that address clot formation

Earlier this week, the BBC reported that one-third of COVID-19 patients developed dangerous blood clots.

19 May 2020

Common cytokine profile in ARDS, severe COVID-19 and sepsis

Many lives have been lost to the severe pneumonic disease COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), during the ongoing pandemic. The reason for the critical lung injury that results in a fatal outcome in a significant minority of patients has been supposed to be the dramatic oversecretion of pro-inflammatory cytokines and chemokines triggered by the virus.

19 May 2020

Multi-institutional clinical trial sheds new light on non-responsive tumors

Over the last decade, enzalutamide and similar drugs have led to significant tumor control and increased survival time for men who have metastatic prostate cancer that continues to grow despite treatments to reduce male hormone levels.

19 May 2020

Three FDA-approved drugs can block the replication of COVID-19 virus

Three drugs that are already approved by the Food and Drug Administration (FDA) or other international agencies can block the production of the novel coronavirus that causes COVID-19 in human cells, according to computational and pharmaceutical studies performed by UT Southwestern scientists.

19 May 2020

Coronavirus pandemic may spark mental health crisis, U.N. warns

A mental health crisis is looming as millions of people are affected by deaths, disease, poverty, and isolation. All of these factors could cause severe psychological distress. The U.N. warns that due to the stress faced by people in physical isolation, a mental health crisis is approaching.

18 May 2020

Scant clinical research for pregnant and lactating women with COVID-19

Pregnant and breastfeeding women have been excluded from clinical trials of drugs to treat COVID-19, and as result, there is no safety data to inform clinical decisions. Such drugs include remdesivir according to a new article in the peer-reviewed journal Breastfeeding Medicine.

18 May 2020

Tocilizumab improves survival in COVID-19 patients with ARDS

The current COVID-19 pandemic caused by the SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2), has already nearly 4.8 million confirmed cases and more than 318,000 deaths.

18 May 2020

Global study to test whether antimalaria drug can prevent COVID-19 in health-care workers

With $9 million in philanthropic support, an international group of physicians and scientists is establishing a research network to evaluate promising therapies for COVID-19.

18 May 2020

Novel microRNA biomarker could help detect lymph node metastases in pancreatic cancer patients

For years, surgeons have operated on pancreatic cancer patients to remove what they thought was a localized tumor only to discover that the disease had spread to other, inoperable parts of the body. Now, a City of Hope molecular scientist thinks he may have found a way to prevent ineffective surgeries and prolong the lives of these patients.

18 May 2020

Drugs News and Research

Immunologists propose possible molecular mechanism for the deadly respiratory syndrome

New technique determines lipid composition in a brain region

New study may eliminate dangerous side effects of drugs used for treating various conditions

New drug treatment can reduce risk of death from COVID-19 infection

MU researchers examine how menopause can impact cognitive function

Understanding why pancreatic ductal adenocarcinoma is so aggressive

DZD researchers discover additional genetic cause for non-alcoholic fatty liver disease

Phase IIB clinical trial initiated for treating hepatitis B-associated liver cancer

Hop supplements used by menopausal women are not likely to cause drug interactions

New technique produces pure therapeutic drugs without the associated side effects

SWOG scientists to deliver online presentations at ASCO20 Virtual Scientific Program

Study highlights need to focus on medications that address clot formation

Common cytokine profile in ARDS, severe COVID-19 and sepsis

Multi-institutional clinical trial sheds new light on non-responsive tumors

Three FDA-approved drugs can block the replication of COVID-19 virus

Coronavirus pandemic may spark mental health crisis, U.N. warns

Scant clinical research for pregnant and lactating women with COVID-19

Tocilizumab improves survival in COVID-19 patients with ARDS

Global study to test whether antimalaria drug can prevent COVID-19 in health-care workers

Novel microRNA biomarker could help detect lymph node metastases in pancreatic cancer patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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