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CRISPR-Cas12a assay to diagnose SARS-CoV-2 infection and detect strain-specific SNPs for variant identification

The multiplex detection approach outlined in this study has the potential to address the need to rapidly characterize the phenotype and clinical response to continually emerging SARS-CoV-2 variants as the COVID-19 pandemic continues.

16 Feb 2022

Features of platelet-immune crosstalk in healthy recipients of two doses of mRNA-based SARS-CoV-2 vaccine BNT162b2

Researchers investigated the role of platelets in the adverse immune response against a COVID-19 vaccine.

16 Feb 2022

The long-term consequences of SARS-CoV-2 infection in people with HIV

In a recent study posted to the medRxiv* preprint server, an interdisciplinary team of researchers from the United States (US) analyzed a cohort of patients with human immunodeficiency virus (HIV) (PWH) recovering from coronavirus disease 2019 (COVID-19) and characterized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific immune responses in these patients.

15 Feb 2022

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

In a recent study posted to the medRxiv* preprint server, researchers evaluated if folic acid or methotrexate use impacts the risk of coronavirus disease 2019 (COVID-19) diagnosis or associated mortality in the United Kingdom (UK).

15 Feb 2022

Use of immunosuppressants for inflammatory rheumatic diseases and the associated risk of severe COVID-19

A recent study posted to the medRxiv* preprint server investigated the risk of severe/fatal coronavirus disease 2019 (COVID-19) in patients treated with immunosuppressants for inflammatory rheumatic diseases (IRD).

15 Feb 2022

Stem cell infusion improves the survival of mice with sepsis

A one-time infusion of stem cells from bone marrow improves the survival of mice with sepsis, shows a study published today in eLife.

15 Feb 2022

Research suggests SARS-CoV-2 viral accessory proteins may play significant role in viral evolution

Researchers investigate SARS-CoV-2 mutations present across the whole genome of different SARS-CoV-2 variants.

15 Feb 2022

Prediction of SARS-CoV-2 epitope candidates for future vaccines

Researchers identify and investigate the presence and evolution of the SARS-CoV-2 N and S glycoprotein proteins.

15 Feb 2022

The in vitro selection of a remdesivir-resistant SARS-CoV-2 mutation

Researchers select and study an RDV-resistant virus by serial passaging of wild type SARS-CoV-2 in the presence of increasing concentrations of RDV.

15 Feb 2022

Researchers create a comprehensive atlas of cerebrovascular cell types

While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

15 Feb 2022

New approach to alter the skin microbiome and reduce acne lesions using bacteria

Acne on the face is often treated with topical antibiotics, which tend to be used for an extended period of time and contribute to the serious problem of antibiotic resistance.

15 Feb 2022

Researchers find potential new strategy to treat metastatic form of intra-abdominal cancer

Researchers from the National Cancer Centre Singapore (NCCS) have found a potential new strategy to treat peritoneal carcinomatosis, a metastatic form of intra-abdominal cancer, where patients are presented with limited treatment options and poor overall survival.

15 Feb 2022

Incomplete repair of the damaged lung may contribute to death from COVID-19 and non-COVID ARDS

Investigators studying lung cells have discovered that the normal repair process that occurs after lung disease or injury appears to be incomplete but still ongoing in patients who died of COVID-19 and non-COVID acute respiratory distress syndrome (ARDS).

15 Feb 2022

Study lays the groundwork for developing novel ways to promote tissue regeneration

A study conducted at the University of Helsinki lays the groundwork for the development of future ways to promote tissue regeneration in, for example, degenerative diseases or accelerate recovery from tissue damage.

15 Feb 2022

Novel combination therapeutic approach could increase survival of pancreatic cancer patients

A novel combination treatment approach extended survival in mice with pancreatic cancer, demonstrating a potential second-line therapy for patients, according to findings published in Proceedings of the National Academy of Sciences.

15 Feb 2022

A third known case of HIV remission involving stem cell transplant documented

A woman with HIV who received a cord blood stem cell transplant to treat acute myeloid leukemia has had no detectable levels of HIV for 14 months despite cessation of antiretroviral therapy (ART), according to a presentation at today's Conference on Retroviruses and Opportunistic Infections (CROI).

15 Feb 2022

B Cell News and Research

CRISPR-Cas12a assay to diagnose SARS-CoV-2 infection and detect strain-specific SNPs for variant identification

Features of platelet-immune crosstalk in healthy recipients of two doses of mRNA-based SARS-CoV-2 vaccine BNT162b2

The long-term consequences of SARS-CoV-2 infection in people with HIV

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

Use of immunosuppressants for inflammatory rheumatic diseases and the associated risk of severe COVID-19

Stem cell infusion improves the survival of mice with sepsis

Research suggests SARS-CoV-2 viral accessory proteins may play significant role in viral evolution

Prediction of SARS-CoV-2 epitope candidates for future vaccines

The in vitro selection of a remdesivir-resistant SARS-CoV-2 mutation

Researchers create a comprehensive atlas of cerebrovascular cell types

New approach to alter the skin microbiome and reduce acne lesions using bacteria

Researchers find potential new strategy to treat metastatic form of intra-abdominal cancer

Incomplete repair of the damaged lung may contribute to death from COVID-19 and non-COVID ARDS

Study lays the groundwork for developing novel ways to promote tissue regeneration

Novel combination therapeutic approach could increase survival of pancreatic cancer patients

A third known case of HIV remission involving stem cell transplant documented

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

Study investigates whether SARS-CoV-2 infection is associated with increased risk of incident type 1 diabetes

Study describes sequelae presenting more than six months after COVID-19 in non-hospitalized young adults

Novel glycation patterns help understand Omicron immune escape

Using single B cell screening to boost antibody discovery eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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