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Sangamo BioSciences starts trial of CCR5-ZFP therapeutic to treat HIV/AIDS

Sangamo BioSciences, Inc. has announced that its collaborators at the University of Pennsylvania have opened a Phase 1 clinical trial to evaluate SB-728-T for the treatment of HIV/AIDS.

5 Feb 2009

Molecule that suppresses immune response under study in type 1 diabetes

The idea is to teach the immune system of children at high risk for type 1 diabetes not to attack the insulin-producing cells of the pancreas.

5 Feb 2009

Discovery of crucial molecule in cancer rejection

Researchers at the Centenary Institute in Sydney have discovered a molecule on the surface of immune cells which plays a critical role in cancer rejection.

5 Feb 2009

Researchers find pathway and enzyme unique to tularemia organism

Researchers are closer to developing therapies to combat the deadly tularemia infection, according to a study published this week in the Proceedings of the National Academy of Sciences' online Early Edition.

3 Feb 2009

Capn4 protein predicts liver cancer recurrence and after transplantation

A new study suggests that Capn4, a protein involved in cell migration, is associated with liver cancer recurrence and metastasis after liver transplantation.

3 Feb 2009

New findings raise questions about process used to identify experimental drug

A study by National Institutes of Health (NIH) researchers has revealed surprising new insights into the process used to initially identify an experimental drug now being tested in people with cystic fibrosis and muscular dystrophy.

3 Feb 2009

Green tea may counteract anticancer effects of cancer therapy, bortezomib (Velcade)

Green tea products have become regarded as a valuable health supplement, as studies have shown evidence of its benefit against a variety of diseases, including cancer.

3 Feb 2009

New inhibitors could be new class of cancer drugs

A team of Vanderbilt University Medical Center investigators has developed a group of chemical compounds that could represent a new class of drugs for treating cancer.

3 Feb 2009

Heart drug improve learning and memory in middle-aged rats

A team of Arizona psychologists, geneticists and neuroscientists has reported that a safe and effective drug used to treat vascular problems in the brain has improved spatial learning and working memory in middle-aged rats.

2 Feb 2009

Fasudil could reduce risk of Alzheimer's

A drug used to improve blood flow to the brain also could help improve learning and memory and reduce the risk of Alzheimer's disease, according to a new study released today by investigators at the Translational Genomics Research Institute (TGen) and Arizona State University.

2 Feb 2009

Quantum dot hazards

Quantum dots have the potential to bring many good things into the world: efficient solar power, targeted gene and drug delivery, solid-state lighting and advances in biomedical imaging among them.

2 Feb 2009

Inflammation in colon may get doused before fueling cancer development

A tiny molecule found in most plant-based foods douses the flames before damaging lesions can form in the colon, according to a study by Texas AgriLife Research scientist Dr. Nancy Turner.

2 Feb 2009

Stress may speed growth of melanoma tumors

For patients with a particularly aggressive form of skin cancer - malignant melanoma - stress, including that which comes from simply hearing that diagnosis, might amplify the progression of their disease.

2 Feb 2009

Scientists develop sophisticated model to help researchers apply physics and mathematics concepts to cancer

Biology exists in a physical world. That's a fact cancer researchers are beginning to recognize as they look to include concepts of physics and mathematics in their efforts to understand how cancer develops -- and how to stop it.

2 Feb 2009

New compound shows potential as tuberculosis drug

Rajesh Gokhale has created a compound in his lab in India that stops tuberculosis in its tracks.

2 Feb 2009

Reduce the calories and increase that brain power!

According to a study conducted by researchers in Germany older people benefit from a calorie restricted diet in more ways than one - they lose weight but also improve their memories.

28 Jan 2009

Researchers create precise biosensor for detecting blood glucose

Researchers have created a precise biosensor for detecting blood glucose and potentially many other biological molecules by using hollow structures called single-wall carbon nanotubes anchored to gold-coated "nanocubes."

23 Jan 2009

First '3D movie' of tumour protein gives new drug hope

First '3D movie' of tumour protein gives new drug hope CANCER RESEARCH UK scientists have created the first complete model of a molecule which captains a key cell signalling network to prevent cancer - and exposed the secret of how a highly selective drug can intervene to control its activity, according to a study published in PLoS Biology.

23 Jan 2009

Lisofylline drug improves type 2 insulin action; reduces harm of fat in preclinical study

Results of a preclinical study involving DiaKine Therapeutics' lead drug candidate Lisofylline (LSF) indicate the compound may reduce two key risk factors for type 2 diabetes.

23 Jan 2009

Topical treatment wipes out herpes with RNAi

Whether condoms or abstinence, most efforts to prevent sexually transmitted diseases have a common logic: keep the pathogen out of your body altogether.

21 Jan 2009