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Link between mouthwash and oral cancer in dispute

A battle has broken out between dental health experts over claims by an academic researcher that the alcohol present in mouthwash products increases the risk of oral of cancer.

12 Jan 2009

Researchers find link between two aging pathways in mice

Two previously identified pathways associated with aging in mice are connected, say researchers at the Stanford University School of Medicine.

9 Jan 2009

Discovery of new molecule in blood-pressure control system

Researchers at Oregon Health & Science University's School of Dentistry have discovered that the nerve cells controlling heart rate and blood pressure synthesize a molecule known to be critically important for proper nervous system growth.

8 Jan 2009

Novel low-cost immunotherapy for cancer cells

Molecules of sugar sitting on the surface of cancer cells are keys to the development of a new vaccine aimed at both treating and stopping the spread of certain types of cancers called carcinomas, which include prostate, breast, ovarian and lung, among others.

8 Jan 2009

First artemisinin based malaria drug may meet resistance, expert says

This year, the U.S. Food and Drug Administration is expected to approve the first malaria drug to contain artemisinin, a wormwood derivative from China that has proven effective for malaria in Africa and Asia.

8 Jan 2009

New cataract early detection device

A compact fiber-optic probe developed for the space program has now proven valuable for patients in the clinic as the first non-invasive early detection device for cataracts, the leading cause of vision loss worldwide.

8 Jan 2009

Phase III studies of EXPAREL (DepoBupivacaine) from Pacira complete enrollment

Pacira Pharmaceuticals, Inc., an acute care specialty pharmaceutical company, announced today that enrollment has been completed in two pivotal Phase III SIMPLE trials to evaluate the safety and efficacy of a single intraoperative administration of EXPAREL(TM) (DepoBupivacaine) for prolonged postoperative analgesia.

6 Jan 2009

Sildenafil may help protect heart from high blood pressure damage

Johns Hopkins and other researchers report what is believed to be the first direct evidence in lab animals that the erectile dysfunction drug sildenafil amplifies the effects of a heart-protective protein.

5 Jan 2009

New insight into critical molecular mechanisms involved in aggressive childhood cancer

A new study reveals critical molecular mechanisms associated with the development and progression of human neuroblastoma, the most common cancer in young children.

5 Jan 2009

New methods for studying DNA repair and protein modification

This month's issue of Cold Spring Harbor Protocols features two articles detailing experimental methods for the analysis of molecular processes involved in DNA repair and post-translational modification of proteins.

5 Jan 2009

Cylene Pharmaceuticals starts CX-4945 trial - first-in class inhibitor of CK2

Cylene Pharmaceuticals announced today that it has initiated a Phase I clinical trial of its oral CK2 protein kinase inhibitor, CX-4945, in patients with advanced solid tumors, Castleman's disease, or multiple myeloma.

5 Jan 2009

Researchers use nanoparticles to make 3-D DNA nanotubes

Arizona State University researchers Hao Yan and Yan Liu imagine and assemble intricate structures on a scale almost unfathomably small.

1 Jan 2009

Study links MiR-29 molecule to muscle maturation, muscle cancer

Researchers at The Ohio State University Comprehensive Cancer Center have discovered that a molecule implicated in leukemia and lung cancer is also important in muscle repair and in a muscle cancer that strikes mainly children.

1 Jan 2009

Laminin-111 shows potential for congenital muscular dystrophy

Current research suggests laminin, a protein that helps cells stick together, may lead to enhanced muscle repair in muscular dystrophy.

1 Jan 2009

Discovery of molecule that targets brain tumors

UC Davis Cancer Center researchers report today the discovery of a molecule that targets glioblastoma, a highly deadly form of cancer.

30 Dec 2008

Matrix fragments trigger fatal excitement

Shredded extracellular matrix (ECM) is toxic to neurons. Chen et al. reveal a new mechanism for how ECM demolition causes brain damage. The study will appear in the December 29, 2008 issue of The Journal of Cell Biology (www.jcb.org).

30 Dec 2008

Measuring nanoparticle behavior in the body using MRI

One of the key steps in the development of any drug or imaging agent intended for human use is measurement of the adsorption, metabolism, and excretion of the drug.

29 Dec 2008

Cardiovascular system proteins play a role in Alzheimer's

Researchers have found that two proteins which work in tandem in the brain's blood vessels present a double whammy in Alzheimer's disease.

22 Dec 2008

Blocking mechanism found for antibiotic resistance in bacteria

It's as simple as A, T, G, C. Northwestern University scientists have exploited the Watson-Crick base pairing of DNA to provide a defensive tool that could be used to fight the spread of antibiotic resistance in bacteria -- one of the world's most pressing public health problems.

18 Dec 2008

Evidence that Alzheimer's disease affects women differently than men

Nearly 4.5 million people suffer from Alzheimer's disease (AD) in our country, and more than half of them are women, according to the National Institute on Aging in Bethesda, Md.

18 Dec 2008