Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

New study heightens concerns over detrimental impact of air pollution on gene associated with AD risk

A new study by researchers at the Universities of Montana, Valle de México, Boise State, and North Carolina, the Centro de Ciencias de la Atmósfera, Universidad Nacional Autónoma de México, Instituto Nacional de Pediatría, and Centro Médico Cozumel heightens concerns over the detrimental impact of air pollution on hippocampal metabolites as early markers of neurodegeneration in young urbanites carrying an allele 4 of the apolipoprotein E gene (APOE).

26 Sep 2015

Study identifies link between kidney stones in children and atherosclerosis

A recent study published in The Journal of Pediatrics is the first to examine and identify a link between kidney stones in children and thickened or hardened arteries — precursors to a wide variety of cardiovascular diseases. Understanding the connection between kidney stones and cardiovascular risk factors in children may help physicians and parents implement prevention measures to reduce future risk of stroke, heart attack or other forms of vascular disease for affected children.

21 Sep 2015

CardioDx announces national agreement with Quest Diagnostics to expand access to Corus CAD blood test

CardioDx, Inc., a molecular diagnostics company specializing in cardiovascular genomics, today announced a national specimen-draw agreement with Quest Diagnostics DGX, +1.23% the world's leading provider of diagnostic information services, that will expand patient and clinician access to the Corus CAD lab-developed blood test for aiding the assessment of obstructive coronary artery disease (CAD).

From Quest Diagnostics 18 Sep 2015

Studies show AHA's Life's Simple 7 and Diabetes Shared Care Program reduce lifetime risk of heart failure

One in four middle-aged adults who survive to age 85 will develop heart failure, according to current estimates.

15 Sep 2015

Researchers link molecular dots between periodontitis and heart disease

Periodontitis is a risk factor for heart disease. Now a team of researchers has shown that a periodontal pathogen causes changes in gene expression that boost inflammation and atherosclerosis in aortic smooth muscle cells. The research is published ahead of print in Infection and Immunity, a journal of the American Society for Microbiology.

14 Sep 2015

Researchers find answer to continuing debate in the cardiovascular scientific world

Researchers from the University of Ottawa Heart Institute, together with the teams of Dr. Martin Farrell at Oxford University, and Dr. Sekar Kathiresan at the Broad Institute, have found the answer to an ongoing debate in the cardiovascular scientific world. Dr. Ruth McPherson and Dr. Majid Nikpay, researchers at the UOHI's Ruddy Canadian Cardiovascular Genetics Centre, report that the genetic basis of heart disease is largely derived from the cumulative effect of multiple common genetic variants, rather than from a few rare variants with large effects.

9 Sep 2015

Novel approach to reduce 'bad' lipids in blood circulation

Xian-Cheng Jiang, PhD, professor of cell biology at SUNY Downstate Medical Center, has led a study identifying a new approach for lowering "bad" lipids in blood circulation, a critical means to combat devastating cardiovascular diseases such as atherosclerosis. The research was published in the online edition of Gastroenterology.

3 Sep 2015

Treatment with life-saving medications increases in IHD but levels still suboptimal

Treatment with life-saving medications has increased over the past ten years in ischaemic heart disease but levels are still suboptimal, according to the first results of the Chronic Ischaemic Cardiovascular Disease (CICD) Pilot Registry presented today at ESC Congress 2015 and published in European Heart Journal.

2 Sep 2015

Study: Retrieval of larger thrombi during IAT linked to improved neurological recovery after acute ischaemic stroke

Retrieval of larger thrombi during intra arterial treatment (IAT) is associated with improved neurological recovery after acute ischaemic stroke, according to a sub study of the MR CLEAN trial presented at ESC Congress today by Dr Anouchska Autar, PhD candidate at the Erasmus Medical Centre in Rotterdam, the Netherlands.

1 Sep 2015

Key modifiable Alzheimer’s risk factors pinpointed

A meta-analysis has identified the key modifiable factors associated with an increased or decreased risk of Alzheimer’s disease.

27 Aug 2015

Computational fluid dynamics modeling confirms better blood flow with new stent graft design

Vascular surgeon Pat Kelly of Sanford Health in Sioux Falls, South Dakota, knew his patients were doing better with the stent graft he designed, but he wanted a better understanding of the mechanics before testing the device more widely in a clinical trial. For that, he reached out to South Dakota State University.

27 Aug 2015

Commonly used heart attack blood test may identify people at risk for hypertension

Analysis of blood samples from more than 5,000 people suggests that a more sensitive version of a blood test long used to verify heart muscle damage from heart attacks could also identify people on their way to developing hypertension well before the so-called silent killer shows up on a blood pressure machine.

27 Aug 2015

Alpha lipoic acid can stimulate telomerase with positive effects in mouse model of atherosclerosis

In human cells, shortened telomeres, the protective caps at the ends of chromosomes, are both a sign of aging and contribute to it. Scientists at Emory University School of Medicine have found that the dietary supplement alpha lipoic acid (ALA) can stimulate telomerase, the enzyme that lengthens telomeres, with positive effects in a mouse model of atherosclerosis.

24 Aug 2015

New study explains why statins are more beneficial than others in some cases

Statins' success in reducing atherosclerosis-related events has elevated the medications to wonder-drug status, with some researchers advocating for their wider use as a preemptive therapy for cardiovascular disease.

13 Aug 2015

Depressive symptoms, stress, anxiety and anger in RA patients linked to atherosclerosis

New research reveals that depressive symptoms, stress, anxiety, and anger and lack of social support in patients with rheumatoid arthritis (RA) were linked to atherosclerosis--a build-up of fatty deposits in the arteries that contributes to cardiovascular disease. The study published in Arthritis Care & Research, a journal of the American College of Rheumatology, suggests that screening and treatment of psychosocial symptoms may curb the cardiovascular disease burden in RA patients.

13 Aug 2015

Testosterone administration not associated with atherosclerosis progression among older men

Among older men with low testosterone levels, testosterone administration for 3 years compared with placebo did not result in a significant difference in the rates of change in atherosclerosis (thickening and hardening of artery walls), nor was it associated with improved overall sexual function or health-related quality of life, according to a study in the August 11 issue of JAMA.

12 Aug 2015

TEAAM trial finds that testosterone has no effect on atherosclerosis progression

Testosterone sales have grown rapidly over the last decade, but few studies have examined the long-term effects of taking testosterone on cardiovascular health and other important outcomes. This week, investigators from Brigham and Women's Hospital report the results of the Testosterone's Effects on Atherosclerosis Progression in Aging Men (TEAAM) trial in the Journal of the American Medical Association.

12 Aug 2015

New Johns Hopkins study shows hepatitis C infection may spell heart trouble

People infected with the hepatitis C virus are at risk for liver damage, but the results of a new Johns Hopkins study now show the infection may also spell heart trouble.

12 Aug 2015

Results of IPC survey identifying 21 psoriasis research priorities published in British Journal of Dermatology

The British Journal of Dermatology has published online the results of an International Psoriasis Council (IPC) survey identifying 21 psoriasis research priorities. The results will also appear in a future print edition of the journal.

6 Aug 2015

Metformin drug has impact on blood fat levels

Besides affecting the blood sugar levels, the substance Metformin, also has an impact on blood fat levels. This was elucidated by an interdisciplinary team of the German Center for Diabetes Research headed by Dr. Rui Wang-Sattler of the Helmholtz Zentrum München. Especially the harmful LDL cholesterol can be reduced.

6 Aug 2015

Atherosclerosis News and Research

Further Reading

New study heightens concerns over detrimental impact of air pollution on gene associated with AD risk

Study identifies link between kidney stones in children and atherosclerosis

CardioDx announces national agreement with Quest Diagnostics to expand access to Corus CAD blood test

Studies show AHA's Life's Simple 7 and Diabetes Shared Care Program reduce lifetime risk of heart failure

Researchers link molecular dots between periodontitis and heart disease

Researchers find answer to continuing debate in the cardiovascular scientific world

Novel approach to reduce 'bad' lipids in blood circulation

Treatment with life-saving medications increases in IHD but levels still suboptimal

Study: Retrieval of larger thrombi during IAT linked to improved neurological recovery after acute ischaemic stroke

Key modifiable Alzheimer’s risk factors pinpointed

Computational fluid dynamics modeling confirms better blood flow with new stent graft design

Commonly used heart attack blood test may identify people at risk for hypertension

Alpha lipoic acid can stimulate telomerase with positive effects in mouse model of atherosclerosis

New study explains why statins are more beneficial than others in some cases

Depressive symptoms, stress, anxiety and anger in RA patients linked to atherosclerosis

Testosterone administration not associated with atherosclerosis progression among older men

TEAAM trial finds that testosterone has no effect on atherosclerosis progression

New Johns Hopkins study shows hepatitis C infection may spell heart trouble

Results of IPC survey identifying 21 psoriasis research priorities published in British Journal of Dermatology

Metformin drug has impact on blood fat levels

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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