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Landmark RSI trial reshapes sedative selection for emergency airway management

Doctors treating seriously ill patients in an emergency setting may want to give the sedative etomidate, rather than ketamine, while placing a breathing tube, according to a randomized trial published in the New England Journal of Medicine.

9 Dec 2025

Prevention efforts for cannabis-impaired driving should also focus on older adults

With cannabis-related vehicle crashes on the rise, a new study suggests that prevention campaigns shouldn't focus just on young people.

9 Dec 2025

Small molecule discovery could open the door to new class of treatments for hard-to-treat cancers

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a small molecule that can inhibit a cancer-driving protein long considered impossible to target with drugs - a discovery that could open the door to a new class of treatments for leukemia and other hard-to-treat cancers.

9 Dec 2025

WSU researchers discover how a neural circuit drives relapse after opioid use

Washington State University researchers have discovered how a neural circuit – or a connection between two brain regions – drives relapse after opioid use, a finding that could lead to more effective treatments for opioid use disorders.

9 Dec 2025

Australian researchers pinpoint specific genetic changes linked to severe AMD

Australian researchers have for the first time pinpointed specific genetic changes that increase the risk of severe, sight-threatening forms of age-related macular degeneration (AMD).

9 Dec 2025

Online reference library provides a more accurate picture of drug exposure

Doctors and researchers try to understand what medications a person has taken by asking patients directly or by looking at medical records. But this information is often incomplete.

9 Dec 2025

Study reveals how brain protein KCC2 influences reward learning

A new finding from researchers at Georgetown University Medical Center shows that the learning process of associating cues with rewards can be altered by increased or decreased activity of a specific protein in the brain.

9 Dec 2025

Genome-edited immune cell therapy shows promise for treating aggressive blood cancer

A groundbreaking new treatment using genome-edited immune cells, developed by scientists at UCL (University College London) and Great Ormond Street Hospital (GOSH), has shown promising results in helping children and adults fight a rare and aggressive form of blood cancer called T-cell acute lymphoblastic leukemia (T-ALL).

8 Dec 2025

Older chemical libraries yield new leads for next-generation COVID-19 antivirals

SARS‑CoV‑2, the virus that causes COVID-19, continues to mutate, with some newer strains becoming less responsive to current antiviral treatments like Paxlovid.

8 Dec 2025

Study reveals new genetic insights into reticular pseudodrusen in people with AMD

A study funded in part by the National Institutes of Health (NIH) has revealed important insights into the genetics of deposits in the eye, known as reticular pseudodrusen (RPD), that are linked to greater risk of vision loss among people with age-related macular degeneration (AMD).

8 Dec 2025

Most T-cell/histocyte-rich large B-cell lymphoma patients can safely receive a less toxic treatment

Most patients with a rare and aggressive form of large B-cell lymphoma can safely receive a less toxic treatment than the intensive chemotherapy often used, according to new research from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.

8 Dec 2025

Understanding the heterogeneity in nicotine, tobacco, and cannabis use among young Americans

Young Americans use nicotine, tobacco and cannabis in multiple ways, but smoking those items––the most dangerous method––is still involved for most users, a new University of Michigan study found.

8 Dec 2025

AI method could help clinicians accurately identify brain tumors and radiation necrosis

While targeted radiation can be an effective treatment for brain tumors, subsequent potential necrosis of the treated areas can be hard to distinguish from the tumors on a standard MRI.

8 Dec 2025

Intellicule secures $217,941 SBIR Phase I grant to develop biomolecular modeling software

Intellicule, a software company whose solutions determine the 3D structures of biomolecules imaged with cryogenic-electron microscopy (cryo-EM), has received a $217,941 Small Business Innovation Research (SBIR) Phase I grant from the National Institutes of Health.

8 Dec 2025

NYS Medical Cannabis Program reduces chronic pain patients' reliance on opioids

Adults with chronic pain who participated in New York State's (NYS) Medical Cannabis Program were significantly less likely to require prescription opioids, according to a new study published today in JAMA Internal Medicine and led by researchers at Albert Einstein College of Medicine and Montefiore Health System.

8 Dec 2025

Researchers discover a surprising ally in the fight against insulin resistance and type 2 diabetes

An international research team led by Professor Marc-Emmanuel Dumas at Imperial College London & CNRS together with Prof. Patrice Cani (Imperial & University of Louvain, UCLouvain), Dr. Dominique Gauguier (Imperial & INSERM, Paris) and Prof. Peter Liu (University of Ottawa Heart Institute) has uncovered a surprising ally in the fight against insulin resistance and type 2 diabetes: a microbial metabolite called trimethylamine (TMA).

8 Dec 2025

Novel wireless device uses light to send information directly to the brain

In a new leap for neurobiology and bioelectronics, Northwestern University scientists have developed a wireless device that uses light to send information directly to the brain - bypassing the body's natural sensory pathways.

8 Dec 2025

JAX wins $30 million contract to create computational "digital twins" of the human heart

Developing new drugs is one of the riskiest and most expensive endeavors in science. Today, The Jackson Laboratory (JAX) announced a bold initiative to improve that trajectory, powered by an up to $30 million contract from the Advanced Research Projects Agency for Health (ARPA-H) Computational ADME-Tox and Physiology Analysis for Safer Therapeutics (CATALYST) program.

8 Dec 2025

Receiving immunotherapy earlier in the day may improve survival in cancer patients

Receiving anticancer immunotherapy earlier in the day may help individuals with cancer live longer. That's according to a study published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.

8 Dec 2025

Fixed-duration therapy works as effectively as continuous treatment for chronic lymphocytic leukemia

According to a new trial, patients with chronic lymphocytic leukemia (CLL) show comparable outcomes whether they receive a single-agent treatment indefinitely or a combination treatment for a fixed period of time.

7 Dec 2025

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Drugs News and Research

Landmark RSI trial reshapes sedative selection for emergency airway management

Prevention efforts for cannabis-impaired driving should also focus on older adults

Small molecule discovery could open the door to new class of treatments for hard-to-treat cancers

WSU researchers discover how a neural circuit drives relapse after opioid use

Australian researchers pinpoint specific genetic changes linked to severe AMD

Online reference library provides a more accurate picture of drug exposure

Study reveals how brain protein KCC2 influences reward learning

Genome-edited immune cell therapy shows promise for treating aggressive blood cancer

Older chemical libraries yield new leads for next-generation COVID-19 antivirals

Study reveals new genetic insights into reticular pseudodrusen in people with AMD

Most T-cell/histocyte-rich large B-cell lymphoma patients can safely receive a less toxic treatment

Understanding the heterogeneity in nicotine, tobacco, and cannabis use among young Americans

AI method could help clinicians accurately identify brain tumors and radiation necrosis

Intellicule secures $217,941 SBIR Phase I grant to develop biomolecular modeling software

NYS Medical Cannabis Program reduces chronic pain patients' reliance on opioids

Researchers discover a surprising ally in the fight against insulin resistance and type 2 diabetes

Novel wireless device uses light to send information directly to the brain

JAX wins $30 million contract to create computational "digital twins" of the human heart

Receiving immunotherapy earlier in the day may improve survival in cancer patients

Fixed-duration therapy works as effectively as continuous treatment for chronic lymphocytic leukemia

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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