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Mildly stressing muscle metabolism reverses diabetes and obesity in mice

Mildly stressing muscle metabolism boosts levels of a beneficial hormone that prevents obesity and diabetes in mice, according to a new study by researchers at the University of Iowa.

28 Jun 2017

Chicken models may shed light on how humans develop sensitive daytime vision

Humans belong to a select club of species that enjoy crisp color vision in daylight, thanks to a small spot in the center of the retina at the back of the eye.

23 Jun 2017

Two-test combination accurately identifies benign pancreatic lesions

When performed in tandem, two molecular biology laboratory tests distinguish, with near certainty, pancreatic lesions that mimic early signs of cancer but are completely benign.

23 Jun 2017

Existing drugs could help subgroup of patients with osteosarcoma, suggest scientists

A subgroup of patients with osteosarcoma - a form of bone cancer - could be helped by an existing drug, suggest scientists from the Wellcome Trust Sanger Institute and their collaborators at University College London Cancer Institute and the Royal National Orthopaedic Hospital NHS Trust.

23 Jun 2017

Human colon organoids fill gap in effectively modeling common GI diseases

Scientists used human pluripotent stem cells to generate human embryonic colons in a laboratory that function much like natural human tissues when transplanted into mice, according to research published June 22 in Cell Stem Cell.

22 Jun 2017

Scientists design bioactive nanomaterial that excels at stimulating bone regeneration

There hasn't been a gold standard for how orthopaedic spine surgeons promote new bone growth in patients, but now Northwestern University scientists have designed a bioactive nanomaterial that is so good at stimulating bone regeneration it could become the method surgeons prefer.

19 Jun 2017

New approach could potentially prevent muscle wasting in muscular dystrophy and cancer

Monash University's Biomedicine Discovery Institute researchers have collaboratively developed a therapeutic approach that dramatically promotes the growth of muscle mass, which could potentially prevent muscle wasting in diseases including muscular dystrophy and cancer.

14 Jun 2017

Melbourne study offers hope for better lung cancer treatment

A Melbourne study is set to improve treatment options for patients with the second most common type of lung cancer, lung squamous cell carcinoma, a disease for which new anti-cancer drugs are urgently needed.

13 Jun 2017

New treatment strategy may destroy difficult-to-treat brain tumors

A new strategy for treating brain tumors may extend or save the lives of patients diagnosed with one of the deadliest forms of cancer, according to a study from UT Southwestern Medical Center.

13 Jun 2017

Single bout of exercise can have significant positive behavioral and cognitive effects

In a new review of the effects of acute exercise published in Brain Plasticity, researchers not only summarize the behavioral and cognitive effects of a single bout of exercise, but also summarize data from a large number of neurophysiological and neurochemical studies in both humans and animals showing the wide range of brain changes that result from a single session of physical exercise.

12 Jun 2017

Study suggests promising therapeutic strategy for childhood brain tumor

A study published in Molecular Cancer Research reveals that a tumor suppressor gene p16 is turned off by a histone mutation (H3.3K27M), which is found in up to 70 percent of childhood brain tumors called diffuse intrinsic pontine glioma (DIPG).

6 Jun 2017

Researcher discovers treatment strategy to attack metastatic cancers that have spread to the brain

Rakesh Jain, PhD, Director of the Edwin L. Steele Laboratory for Tumor Biology at the Massachusetts General Hospital and supported by the National Foundation for Cancer Research, has discovered a novel mechanism behind the resistance to HER2- or PI3K-targeted therapies, and a treatment strategy that may overcome treatment resistance.

6 Jun 2017

Findings point to potential new treatment for people with newly diagnosed EGFR-positive NSCLC

Findings from a phase III clinical trial point to a potential new treatment for patients newly diagnosed with advanced, epidermal growth factor receptor (EGFR)-positive non-small cell lung cancer (NSCLC).

5 Jun 2017

Scientists locate crucial off-switch for central cell control

As the cell's molecular control center, the mTor kinase regulates cellular metabolism, growth and division. However, in cells affected by pathological change, the regulation goes array.

2 Jun 2017

New therapeutic approach could save diabetics from amputation by promoting wound healing

Diabetic patients frequently have lesions on their feet that are very difficult to heal due to poor blood circulation. In cases of serious non-healing infections, a decision to amputate could be made. A new therapeutic approach, presented recently in the Journal of Investigative Dermatology by Canadian researchers affiliated with the University of Montreal Hospital Research Centre, could prevent these complications by promoting wound healing.

29 May 2017

NCCN ORP funds researchers to evaluate targeted treatment in EGFRm+ non-small cell lung cancer

The National Comprehensive Cancer Network Oncology Research Program has funded two investigators from NCCN Member Institutions through a collaborative scientific research relationship with AstraZeneca to further evaluate the clinical effectiveness of osimertinib in the treatment of epidermal growth factor receptor-positive (EGFRm+) non-small cell lung cancer (NSCLC).

25 May 2017

Study findings could lead to quick and new way for predicting efficacy of cancer treatments

Once hailed as a breakthrough in cancer treatment, immunotherapies are now raising concerns as doctors note new side effects like severe allergic reactions, acute-onset diabetes and heart damage.

23 May 2017

Research suggests potential of stem cells to improve tendon healing

New research published online in The FASEB Journal suggests that tendon stem (TSCs) may be able to significantly improve tendon healing by regulating inflammation, which contributes to scar-like tendon healing and chronic matrix degradation.

23 May 2017

IBS scientists uncover biological pathway that contributes to thyroid disorder

A team led by KOH Gou Young, director of the Center for Vascular Research, within the Institute for Basic Science, in collaboration with Chungnam National University, clarified the molecular mechanism to explain how the thyroid and surrounding vascular system change in the most common form of hyperthyroidism.

18 May 2017

Targeted therapy appears to be more effective in preventing lung cancer recurrence

The targeted therapy gefitinib appears more effective in preventing recurrence after lung cancer surgery than the standard of care, chemotherapy.

18 May 2017

Growth Factor News and Research

Mildly stressing muscle metabolism reverses diabetes and obesity in mice

Chicken models may shed light on how humans develop sensitive daytime vision

Two-test combination accurately identifies benign pancreatic lesions

Existing drugs could help subgroup of patients with osteosarcoma, suggest scientists

Human colon organoids fill gap in effectively modeling common GI diseases

Scientists design bioactive nanomaterial that excels at stimulating bone regeneration

New approach could potentially prevent muscle wasting in muscular dystrophy and cancer

Melbourne study offers hope for better lung cancer treatment

New treatment strategy may destroy difficult-to-treat brain tumors

Single bout of exercise can have significant positive behavioral and cognitive effects

Study suggests promising therapeutic strategy for childhood brain tumor

Researcher discovers treatment strategy to attack metastatic cancers that have spread to the brain

Findings point to potential new treatment for people with newly diagnosed EGFR-positive NSCLC

Scientists locate crucial off-switch for central cell control

New therapeutic approach could save diabetics from amputation by promoting wound healing

NCCN ORP funds researchers to evaluate targeted treatment in EGFRm+ non-small cell lung cancer

Study findings could lead to quick and new way for predicting efficacy of cancer treatments

Research suggests potential of stem cells to improve tendon healing

IBS scientists uncover biological pathway that contributes to thyroid disorder

Targeted therapy appears to be more effective in preventing lung cancer recurrence

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

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