Immunization News and Research

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Dominance of South African SARS-CoV-2 variant in the US is unlikely but possible

Researchers in the United States and Canada have conducted a study showing that the South African variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – is unlikely to become the dominant strain in the US.

13 May 2021

Single dose of Oxford-AstraZeneca vaccine protective in previously infected recipients, suggests study

A recent report on the medRxiv* preprint server suggests that a single dose of the Oxford-AstraZeneca (ChAdOx1 nCoV-19) vaccine could elicit higher titers of neutralizing antibodies, effectively acting as a booster dose, in people who have already been infected by the SARS-CoV-2.

13 May 2021

Rheumatologists develop a set of consensus statements on COVID-19 vaccination

Rheumatologists in Hong Kong joined hands to develop a set of consensus statements on COVID-19 vaccination for local adult patients with autoimmune rheumatic diseases. These timely statements would serve to be a guide for rheumatologists, other specialists, family physicians, specialty nurses, and the public regarding COVID-19 vaccination for patients with rheumatic diseases.

13 May 2021

Personalized vaccine can provide effective immunization against cancer

Marie-Claude Bourgeois-Daigneault and her team at the CRCHUM are using mice to show how a combination of peptides and oncolytic viruses, used as an adjuvant, can provide effective immunization against cancer.

11 May 2021

Combo COVID-flu vaccine protects against current and emerging variants in animal model

Now, in new research posted to the bioRxiv preprint server, scientists at Novavax, Inc. present a vaccine including recombinant influenza hemagglutinin (HA) antigen along with recombinant SARS-CoV-2 spike protein, with saponin Matrix-M adjuvant. Both have passed independent safety tests in phase 1 trials.

10 May 2021

Immunosuppression in COVID-19 promotes emergence of multiple immune escape mutants

An interesting new study describes the emergence of several such variants from a chronically immunosuppressed COVID-19 patient, who remained infected for over 170 days before clearing the virus.

7 May 2021

SARS-CoV-2 infection prolongs viral shedding and lymphocyte loss in patients with cancer

Patients with cancer have a more challenging time with infections while undergoing treatment — placing them as high-risk for severe COVID-19 illness and death. However, how the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts with cancer therapies remains poorly understood.

7 May 2021

Israeli study shows real-world efficacy of Pfizer-BioNTech’s COVID-19 vaccine

Researchers have conducted an analysis of nationwide surveillance data from Israel demonstrating the real-world effectiveness of Pfizer-BioNTech’s BNT162b2 vaccine at protecting against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

6 May 2021

Indian SARS-CoV-2 variant shows enhanced host cell entry and immune evasion

A study conducted by researchers in Germany has found that the B.1.617 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has emerged in India entered certain types of lung and intestine cells with slightly increased efficiency compared with the original wild-type strain.

6 May 2021

India's successful program to eliminate polio provides guidance for mass immunization initiatives

As India urgently scales up its vaccination campaign for the COVID-19 virus, a new study which examined the country's successful program to eliminate polio provides guidance on how this and future mass immunization campaigns can be successful, especially in vaccinating hard to reach groups.

6 May 2021

This small Canadian drugmaker wants to make J&J vaccines for poor nations. It needs more than a patent waiver.

Biolyse Pharma Corp., which makes a cancer medication, was gearing up to start making generic biologic drugs, made from living organisms. Then the pandemic hit.

6 May 2021

World Health Organization lists Moderna COVID-19 vaccine for emergency use

Today, WHO listed the Moderna COVID-19 vaccine (mRNA 1273) for emergency use, making it the fifth vaccine to receive emergency validation from WHO.

6 May 2021

Researchers reach new milestone in the development of effective malaria vaccine

Sanaria PfSPZ-CVac" is a live vaccine consisting of infectious Plasmodium falciparum (Pf) malaria parasites that are injected into the subject at the same time as they receive an antimalarial drug.

5 May 2021

Pfizer/BioNTech and Moderna vaccines induce T-cell immunity against SARS-CoV-2

Researchers in the United States have shown that the Pfizer/BioNTech and Moderna messenger RNA (mRNA) vaccines are effective at generating T-cell immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

5 May 2021

Moderna COVID-19 vaccine makes it on WHO Emergency Use Listing

Moderna has announced Emergency Use Listing granted by the World Health Organization for its COVID-19 mRNA vaccine.

4 May 2021

Researchers demonstrate real-world effectiveness of Johnson & Johnson COVID-19 vaccine

Researchers in the United States and India have conducted a study demonstrating the real-world effectiveness of a single dose of Johnson & Johnson’s Ad26.COV2.S vaccine at preventing infection with severe acute respiratory syndrome coronavirus 2 – the agent that causes coronavirus disease 2019 (COVID-19).

3 May 2021

Hopeaphenol inhibits entry of SARS-CoV-2 variants of concern into cells

A new study, released as a preprint on the bioRxiv* server, reports promising results with the natural product hopeaphenol, which successfully prevented the entry of the virus into host cells.

3 May 2021

Detecting rare blood clots was a win, but US vaccine safety system still has gaps

The quick detection of an ultra-rare blood clotting reaction in some Covid-19 vaccine recipients showed the power of a federal warning system for vaccine safety issues, but experts worry that blind spots in the program could hamper detection of other unexpected side effects.

3 May 2021

CVS and Walgreens have wasted more vaccine doses than most states combined

Two national pharmacy chains that the federal government entrusted to inoculate people against Covid-19 account for the lion's share of wasted vaccine doses, according to government data obtained by KHN.

3 May 2021

Vaccines can save lives and safeguard health and well-being

Effectively and safely protecting against disease--this is what makes vaccines a vital and successful public health tool that saves lives and safeguards health and well-being. Today, vaccines shield us from more than 20 life-threatening diseases.

30 Apr 2021

Immunization News and Research

Dominance of South African SARS-CoV-2 variant in the US is unlikely but possible

Single dose of Oxford-AstraZeneca vaccine protective in previously infected recipients, suggests study

Rheumatologists develop a set of consensus statements on COVID-19 vaccination

Personalized vaccine can provide effective immunization against cancer

Combo COVID-flu vaccine protects against current and emerging variants in animal model

Immunosuppression in COVID-19 promotes emergence of multiple immune escape mutants

SARS-CoV-2 infection prolongs viral shedding and lymphocyte loss in patients with cancer

Israeli study shows real-world efficacy of Pfizer-BioNTech’s COVID-19 vaccine

Indian SARS-CoV-2 variant shows enhanced host cell entry and immune evasion

India's successful program to eliminate polio provides guidance for mass immunization initiatives

This small Canadian drugmaker wants to make J&J vaccines for poor nations. It needs more than a patent waiver.

World Health Organization lists Moderna COVID-19 vaccine for emergency use

Researchers reach new milestone in the development of effective malaria vaccine

Pfizer/BioNTech and Moderna vaccines induce T-cell immunity against SARS-CoV-2

Moderna COVID-19 vaccine makes it on WHO Emergency Use Listing

Researchers demonstrate real-world effectiveness of Johnson & Johnson COVID-19 vaccine

Hopeaphenol inhibits entry of SARS-CoV-2 variants of concern into cells

Detecting rare blood clots was a win, but US vaccine safety system still has gaps

CVS and Walgreens have wasted more vaccine doses than most states combined

Vaccines can save lives and safeguard health and well-being

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