Polymerase News and Research

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Increased resistance to human interferons could be a potential driver of SARS-CoV-2 evolution

Researchers compared the potency of 17 human interferons (IFNs) against multiple SARS-CoV-2 variants.

27 Jul 2022

Study shows SARS-CoV-2 impairs interferon production through NSP2-induced repression of mRNA translation

Researchers discovered a SARS-CoV-2 non-structural protein 2 (NSP2)-mediated mechanism by which it suppresses the production of interferon-beta (IFN-β) in host cells.

27 Jul 2022

Novel compound inhibits SARS-CoV-2 replication by binding a genome target

Researchers assessed the biodistribution and safety of SBCoV202, a novel antiviral agent based on antisense technology that can specifically and effectively bind to the SARS-CoV-2 genome target to inhibit SARS-CoV-2 replication.

27 Jul 2022

SARS-CoV-2 Omicron BA.5 neutralization in vaccinated individuals

Researchers assessed the duration of SARS-CoV-2 Omicron BA.5 neutralization in SARS-CoV-2 vaccinated persons.

27 Jul 2022

Sixteen countries reported monkeypox virus infection in humans between April and June 2022

Researchers have analyzed the recent cases related to the monkeypox virus infection.

27 Jul 2022

Population-based cohort study investigates the effect of SARS-CoV-2 infection on pregnancy outcomes

In a new study, researchers have focused on evaluating small-for-gestational-age rates and preterm birth in a large cohort.

27 Jul 2022

Study confirms efficacy of molnupiravir against COVID in a real-life cohort

Researchers report the efficacy and safety of molnupiravir in treating COVID-19.

26 Jul 2022

Naturally-infected, captive white-tailed deer in Texas have persistent anti-SARS-CoV-2 antibodies

Researchers performed a longitudinal study to examine the neutralizing antibody kinetics of a naturally-SARS-CoV-2 infected white-tailed deer population for around 16 months.

26 Jul 2022

BNT162b2 vaccination induces moderate immunity against Omicron variant in children

Researchers evaluated the effectiveness of the BNT162b2 vaccine against the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concern (VOC) Omicron in five to 11-year-old children.

26 Jul 2022

A VSV-based COVID vaccine effective against SARS-CoV-2 variants

A new study discusses the development of recombinant vesicular stomatitis virus COVID-19 vaccines.

25 Jul 2022

New method uses drones to quickly deliver at-home COVID-19 diagnostic tests

Researchers at the Texas A&M University School of Public Health have developed a new COVID-19 test distribution method that uses drones to quickly deliver at-home diagnostic tests to individuals who suspect they have COVID-19.

25 Jul 2022

How prepared are we for a widespread monkeypox outbreak?

In a new study, researchers summarized the epidemiology, etiology, clinical presentation, diagnosis and prevention and treatment strategies for monkeypox (MPX) caused by the monkeypox virus (MPXV).

25 Jul 2022

New RT-PCR platform gives results faster than other COVID-19 tests on the market

For more than 30 years, polymerase chain reaction (PCR) has been the gold standard in molecular diagnostic testing, detecting genetic material, such as those from a virus or from human DNA.

25 Jul 2022

Are Mexican free-tailed bats a SARS-CoV-2 reservoir?

In a new study, investigators analyzed whether Mexican free-tailed bats were a SARS-CoV-2 reservoir.

21 Jul 2022

Pigment epithelium-derived factor ablations may lead to eye aging

Researchers identified that loss of pigment epithelium-derived factor (PEDF) may cause aging in the eye.

21 Jul 2022

Anti-SARS-CoV-2 nucleocapsid antibodies and pre-existing lung diseases may be independent predictors of long COVID

Researchers evaluated the incidence of long coronavirus disease (long COVID) in a demographically diverse population with different disease severities to inform clinicians and future vaccine development strategies.

21 Jul 2022

Is monkeypox a global public-health emergency?

A summary of available knowledge on the monkeypox virus including pathogenicity, risk to the human population, and strategies that can help limit its spread.

20 Jul 2022

Scientists introduce SARS-CoV-2 phenotype screening for identifying novel antiviral drugs

Researchers introduced a phenotypic screening assay for identifying compounds with SARS-CoV-2 inhibition potential based on caspase 3/7 activation.

20 Jul 2022

The clinical, epidemiological, and evolutionary consequences of a potential SARS-CoV-2-related bat virus spillover into humans

A team of scientists from France has recently described the epidemiological and clinical consequences of a bat sarbecovirus infection in humanized mice.

20 Jul 2022

Researchers observe that a combination of oral and nasal swabs would yield better results for detecting SARS-CoV-2

Researchers observed that a combination of oral and nasal swabs would yield better results for detecting SARS-CoV-2.

20 Jul 2022

Polymerase News and Research

Increased resistance to human interferons could be a potential driver of SARS-CoV-2 evolution

Study shows SARS-CoV-2 impairs interferon production through NSP2-induced repression of mRNA translation

Novel compound inhibits SARS-CoV-2 replication by binding a genome target

SARS-CoV-2 Omicron BA.5 neutralization in vaccinated individuals

Sixteen countries reported monkeypox virus infection in humans between April and June 2022

Population-based cohort study investigates the effect of SARS-CoV-2 infection on pregnancy outcomes

Study confirms efficacy of molnupiravir against COVID in a real-life cohort

Naturally-infected, captive white-tailed deer in Texas have persistent anti-SARS-CoV-2 antibodies

BNT162b2 vaccination induces moderate immunity against Omicron variant in children

A VSV-based COVID vaccine effective against SARS-CoV-2 variants

New method uses drones to quickly deliver at-home COVID-19 diagnostic tests

How prepared are we for a widespread monkeypox outbreak?

New RT-PCR platform gives results faster than other COVID-19 tests on the market

Are Mexican free-tailed bats a SARS-CoV-2 reservoir?

Pigment epithelium-derived factor ablations may lead to eye aging

Anti-SARS-CoV-2 nucleocapsid antibodies and pre-existing lung diseases may be independent predictors of long COVID

Is monkeypox a global public-health emergency?

Scientists introduce SARS-CoV-2 phenotype screening for identifying novel antiviral drugs

The clinical, epidemiological, and evolutionary consequences of a potential SARS-CoV-2-related bat virus spillover into humans

Researchers observe that a combination of oral and nasal swabs would yield better results for detecting SARS-CoV-2

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The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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