Polymerase News and Research

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Is monkeypox a global public-health emergency?

A summary of available knowledge on the monkeypox virus including pathogenicity, risk to the human population, and strategies that can help limit its spread.

20 Jul 2022

Scientists introduce SARS-CoV-2 phenotype screening for identifying novel antiviral drugs

Researchers introduced a phenotypic screening assay for identifying compounds with SARS-CoV-2 inhibition potential based on caspase 3/7 activation.

20 Jul 2022

The clinical, epidemiological, and evolutionary consequences of a potential SARS-CoV-2-related bat virus spillover into humans

A team of scientists from France has recently described the epidemiological and clinical consequences of a bat sarbecovirus infection in humanized mice.

20 Jul 2022

Researchers observe that a combination of oral and nasal swabs would yield better results for detecting SARS-CoV-2

Researchers observed that a combination of oral and nasal swabs would yield better results for detecting SARS-CoV-2.

20 Jul 2022

Safety and immunogenicity of Moderna vaccines containing mRNA encoding the spike protein of different SARS-CoV-2 strains

Researchers evaluated the safety and immunogenicity of COVID-19 vaccines against SARS-CoV-2 variants of concern.

20 Jul 2022

Researchers describe viral shedding of monkeypox virus in patients to better understand the possible role of different bodily fluids in disease transmission

Researchers described the shedding of the monkeypox (MPX) virus (MPXV) in Barcelona city of Spain.

20 Jul 2022

Identifying a core human microbiome

Researchers provide a critical review of the concept of the core human microbiome.

19 Jul 2022

Molnupiravir does not induce resistance mutations in SARS-CoV-2 genome

A new study has pointed out that Molnupiravir treatment increases the ratio of transition to transversion mutations in COVID-19 patients and that the treatment does not appear to induce resistance mutations in the SARS-CoV-2 genome.

19 Jul 2022

Study shows how a critical Lassa virus protein drives infection

Lassa fever is a viral illness that is far too common in West Africa. Although it can have a mortality rate of 15 percent in severe cases, up to 90% in pregnant women, and causes deafness in a quarter of survivors, there is no vaccine or antiviral to protect against Lassa virus.

19 Jul 2022

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Researchers reviewed the consequences of infection with sSARS-CoVs on the host DNA damage response.

19 Jul 2022

How effective is previous infection in preventing reinfection with Omicron BA.4/BA.5?

Researchers investigated the protection conferred by previous SARS-CoV-2 infection in preventing reinfection with BA.4 or BA.5 Omicron subvariants in the residents of Qatar.

18 Jul 2022

Researchers develop a rapid, specific, and accurate RT-qPCR-based method to detect and distinguish between Omicron sublineages

Researchers developed a novel, rapid and accurate qRT-PCR-based method to detect Omicron sublineages BA.1/BA.1.1 and BA.2 in patient samples.

18 Jul 2022

Novel nanoligomer approach to treat severe COVID-19

Researchers discuss the biodistribution and safety of a novel nanoligomer SBCoV207, which was used to targeted miR-2392 in a murine model.

17 Jul 2022

Quest Diagnostics starts testing for monkeypox with a real-time PCR test

Starting today, Quest Diagnostics will begin testing for monkeypox. The company has developed a real-time polymerase chain reaction (PCR) test that uses patient swab specimens to qualitatively detect non-variola orthpoxviruses and monkeypox virus DNA.

15 Jul 2022

Polymerase News and Research

Is monkeypox a global public-health emergency?

Scientists introduce SARS-CoV-2 phenotype screening for identifying novel antiviral drugs

The clinical, epidemiological, and evolutionary consequences of a potential SARS-CoV-2-related bat virus spillover into humans

Researchers observe that a combination of oral and nasal swabs would yield better results for detecting SARS-CoV-2

Safety and immunogenicity of Moderna vaccines containing mRNA encoding the spike protein of different SARS-CoV-2 strains

Researchers describe viral shedding of monkeypox virus in patients to better understand the possible role of different bodily fluids in disease transmission

Identifying a core human microbiome

Molnupiravir does not induce resistance mutations in SARS-CoV-2 genome

Study shows how a critical Lassa virus protein drives infection

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

How effective is previous infection in preventing reinfection with Omicron BA.4/BA.5?

Researchers develop a rapid, specific, and accurate RT-qPCR-based method to detect and distinguish between Omicron sublineages

Novel nanoligomer approach to treat severe COVID-19

Quest Diagnostics starts testing for monkeypox with a real-time PCR test

Y chromosome loss in men can lead to deadly heart failure, research shows

Study detects ten avian influenza A viruses in poultry from four provinces in China

The disease burden and clinical severity of the SARS-CoV-2 Omicron BA.2 sublineage outbreak in Shanghai

Study finds SARS-CoV-2 transmission in children and adolescents is lower than adults

GenomeBits representation of SARS-CoV-2 Delta and Omicron genome sequences

Researchers conduct forensic analysis of SARS-CoV-2-related coronaviruses

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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