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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Research may provide new route to prevention and treatment of diabetes

An analysis of the genomes and epigenomes of lean and obese mice and humans has turned up a wealth of clues about how genes and the environment conspire to trigger diabetes, Johns Hopkins researchers say.

6 Jan 2015

Johns Hopkins scientists use genome editing technology to alter human stem cells

A powerful “genome editing” technology known as CRISPR has been used by researchers since 2012 to trim, disrupt, replace or add to sequences of an organism’s DNA.

6 Jan 2015

New findings may lay groundwork of novel treatment for people with Huntington's disease

By adjusting the levels of a key signaling protein, researchers improved motor function and brain abnormalities in experimental animals with a form of Huntington's disease, a severe neurodegenerative disorder.

5 Jan 2015

Luck is a key factor in cancer development

A statistical model that measures the proportion of cancers that develop as a result of random mutations occurring during cell division was published in Science today.

2 Jan 2015

Johns Hopkins scientists create statistical model to measure proportion of cancer incidence

Scientists from the Johns Hopkins Kimmel Cancer Center have created a statistical model that measures the proportion of cancer incidence, across many tissue types, caused mainly by random mutations that occur when stem cells divide.

2 Jan 2015

UT Southwestern researchers target cells' biological clock to kill cancer cells, shrink tumor growth

Cell biologists at UT Southwestern Medical Center have targeted telomeres with a small molecule called 6-thiodG that takes advantage of the cell's 'biological clock' to kill cancer cells and shrink tumor growth.

2 Jan 2015

Top cancer research and clinical developments at Dana-Farber Cancer Institute in 2014

Immunotherapy, genomic profiling, and investigating game-changing drug therapies topped the list of most important cancer research and clinical developments at Dana-Farber Cancer Institute in 2014.

1 Jan 2015

Study shows that reprogramming stem cells can prevent cancer following full body radiation

The body has evolved ways to get rid of faulty stem cells. A University of Colorado Cancer Center study published today in the journal Stem Cells shows that one of these ways is a "program" that makes stem cells damaged by radiation differentiate into other cells that can no longer survive forever.

31 Dec 2014

New therapeutic approach shows potential for treating cancer

Case Western Reserve researchers have identified a two-pronged therapeutic approach that shows great potential for weakening and then defeating cancer cells.

31 Dec 2014

Researchers identify mutations that destabilize DNA structure that turns a gene off

Researchers at the University of Louisville's James Graham Brown Cancer Center have identified for the first time mutations that destabilize a DNA structure that turns a gene off. These mutations occur at four specific sites in what is known as the "hTERT promoter" in more than 75 percent of glioblastomas and melanomas.

24 Dec 2014

Researchers describe key group of small DNA fragments in neurone regulation and maturity

A study led by researchers from the University of Toronto and involving the Centre for Genomic Regulation in Barcelona has described a group of small DNA fragments that are key in neurone regulation and maturity.

24 Dec 2014

Whole-genome sequencing can identify patients' risk for hereditary cancer

UT Southwestern Medical Center cancer researchers have demonstrated that whole-genome sequencing can be used to identify patients' risk for hereditary cancer, which can potentially lead to improvements in cancer prevention, diagnosis, and care.

24 Dec 2014

Next generation sequencing in malignant pleural mesothelioma tumors reveals complex mutational setting

Next generation sequencing in malignant pleural mesothelioma (MPM) tumors shows a complex mutational setting with a high number of genetic alterations in genes involved in DNA repair, cell survival and cell proliferation pathways. Increased accumulation of mutations correlates with early progression of the tumor and decreased survival.

23 Dec 2014

DNA News and Research

Further Reading

Research may provide new route to prevention and treatment of diabetes

Johns Hopkins scientists use genome editing technology to alter human stem cells

New findings may lay groundwork of novel treatment for people with Huntington's disease

Luck is a key factor in cancer development

Johns Hopkins scientists create statistical model to measure proportion of cancer incidence

UT Southwestern researchers target cells' biological clock to kill cancer cells, shrink tumor growth

Top cancer research and clinical developments at Dana-Farber Cancer Institute in 2014

Study shows that reprogramming stem cells can prevent cancer following full body radiation

New therapeutic approach shows potential for treating cancer

Researchers identify mutations that destabilize DNA structure that turns a gene off

Researchers describe key group of small DNA fragments in neurone regulation and maturity

Whole-genome sequencing can identify patients' risk for hereditary cancer

Next generation sequencing in malignant pleural mesothelioma tumors reveals complex mutational setting

Endogenous retroviruses play critical role in body's immune defense against bacterial, viral pathogens

Medical researchers at Saint Louis University bring hope to those in pain and sickness

Experimental Ebola vaccine safe and immunogenic in African population

Study reveals why older people are at higher risk for developing cancer

Offspring of mice treated with drug had delayed onset, reduced symptoms of Huntington's disease

Resveratrol activates ancient stress response in human cells, shows study

Researchers devise new technique to understand how neutrophils move in bodily tissues

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