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Study reveals potential therapeutic target for treating cocaine addiction

A new study explains how cocaine modifies functions in the brain revealing a potential target for therapies aimed at treating cocaine addiction.

22 Apr 2020

Study reveals a new, effective treatment for chronic insomnia

A new treatment for chronic insomnia, transcranial alternating corrent stimulation, has been found to be effective in a study published in Psychotherapy and Psychosomatics.

22 Apr 2020

Scripps Research established international network to find antiviral compounds against COVID-19

With the COVID-19 pandemic continuing to spread around the globe, Scripps Research has quickly established an international network of collaborating scientific laboratories to leverage ReFRAME, the world's leading drug repurposing collection, to find antiviral compounds against the novel coronavirus.

22 Apr 2020

Scientists find gene signature for poor response to standard therapy in rare uterine cancer

Women who don't survive a rare and aggressive uterine cancer called uterine serous carcinoma, have high expression of a group of 73 genes, a score scientists say can help identify these women and improve their outcome.

22 Apr 2020

Antibiotics linked to increased risk of opioid abuse

Taking antibiotics alongside opioids may increase the risk of opioid abuse, according to research in rats recently published in eNeuro.

22 Apr 2020

Scientists identify new mechanisms that offer protection against Marburg infection

A detailed study of the monoclonal antibodies from a person who survived a Marburg infection led researchers to identify novel mechanisms that contribute protection against the disease, according to the latest findings of a collaborative team led by The University of Texas Medical Branch at Galveston and Vanderbilt University Medical Center.

22 Apr 2020

Researchers uncover how cancer cells don their invisibility cloaks

Immunotherapy drugs that target a protein called programmed death ligand 1 (PD-L1) on the surface of cancer cells have quickly become a mainstay to treat many forms of cancer, often with dramatic results. But exactly how cancer cells turn on this protein was not completely understood.

22 Apr 2020

New database of 14,000 known macrolactones could support drug discovery and research

Researchers from North Carolina State University and Collaborations Pharmaceuticals have created a free-to-use database of 14,000 known macrolactones - large molecules used in drug development - which contains information about the molecular characteristics, chemical diversity and biological activities of this structural class.

22 Apr 2020

Research offers clues to how SARS-CoV-2 gets into respiratory tissue and exploits our defenses

What makes SARS-CoV-2, the virus behind COVID-19, such a threat? A new study, led by Jose Ordovas-Montanes, Ph.D. at Boston Children's Hospital and Alex K. Shalek, Ph.D. at MIT, pinpoints the likely cell types the virus infects.

22 Apr 2020

Making long-term research project a translational success

The Digital Health Accelerator (DHA) of the Berlin Institute of Health (BIH) is helping the scientists to make the long-term research project a translational success.

22 Apr 2020

Study shows how tumor cells respond to lack of nutrients

Some solid tumors have a very high growth rate, which often leads to a lack of vascularization due to the impossibility to develop, at the same time, the blood vessels that accompany and nourish it.

21 Apr 2020

Modeling the spread and influence of COVID-19 in China

The rapid spread of the COVID-19 pandemic led Chinese researchers to model the course of the epidemic early in the year. Their study was published in the Journal of Shanghai Jiao Tong University.

21 Apr 2020

Researchers develop new 3D multicomponent dissolvable vaccine platform

In parallel to their current work on a potential coronavirus vaccine, researchers at the University of Pittsburgh School of Medicine have developed a new vaccine delivery system for vaccines using live or attenuated viral vectors: a finger-tip sized patch that contains 400 tiny needles, each just half of one millimeter.

21 Apr 2020

Immunity to coronavirus infection may help stem the pandemic

The raging coronavirus pandemic is causing immense fear and uncertainty across the world. One of the most distressing aspects of COVID-19 disease is the seemingly large number of unknowns. These include the burning question of immunity. Does a person who was sick with the COVID-19 and then recovered or was infected without symptoms, have immunity against re-infection?

21 Apr 2020

USPTO grants patent to TAU scientist for innovative coronavirus vaccine design

Researchers worldwide are racing at breakneck speed to develop potential vaccines and drugs to fight the novel coronavirus, SARS-Cov-2.

21 Apr 2020

Study explores how tweets may influence substance abuse in youth

Substance use by youth remains a significant public health concern. While social media provides youth the opportunity to discuss and display substance use-related beliefs and behaviors, little is known about how posting drug-related content, or viewing posted content influences the beliefs and behaviors of youth relative to substance use.

21 Apr 2020

New study may offer a breakthrough in treating telomere diseases

Capping decades of research, a new study may offer a breakthrough in treating dyskeratosis congenita and other so-called telomere diseases, in which cells age prematurely.

21 Apr 2020

Study uncovers cause of blood-vessel leakiness in eye diseases

Scientists have identified a key step in the process that leads to leaky vessels and harmful swelling in eye diseases, according to a new study published today in eLife.

21 Apr 2020

Many phase II trials overestimate drug efficacy, pose a barrier in drug licensing

Based on a systematic analysis of trials related to rheumatoid arthritis and psoriasis arthritis, a MedUni Vienna study group at the Division of Rheumatology at MedUni Vienna/Vienna General Hospital was able to show that many clinical phase II trials systematically overestimate the efficacy of therapeutics, so that the results of subsequent phase III trials can often be disappointing. Essentially this situation also applies in many other areas.

21 Apr 2020

Antibodies against Imood could be potential treatment for OCD

Mental health conditions such as obsessive compulsive disorder could be treated in a new way using drugs that target the immune system, research suggests.

21 Apr 2020