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Researchers characterize antibody responses to COVID-19 mRNA-based vaccine

A team of scientists from the USA and Canada has recently characterized the antibodies developed against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in response to an mRNA-based coronavirus disease 2019 (COVID-19) vaccine.

10 Mar 2021

Researchers study prevalence of SARS-CoV-2 UK variant at University of Texas

Researchers at the University of Texas at Austin and Santa Fe Institute in the US used quantitative polymerase chain reaction (PCR) data from a surveillance testing program on a large university campus to estimate how fast the new variant spreads. The team used the data to provide local situational information on the COVID-19 pandemic.

10 Mar 2021

Single mRNA vaccine dose may be enough for those previously exposed to SARS-CoV-2

New research supports the notion that those who have recovered from COVID-19, caused by SARS-CoV-2 infection, may only need one dose of an mRNA vaccine to boost immunity.

10 Mar 2021

Neutralizing antibodies may be evolving to keep up with SARS-CoV-2 mutations

Viruses evolve under increased pressure, and new research from The Rockefeller University and University of Massachusetts Medical School in the U.S. suggests our antibodies can as well.

10 Mar 2021

Tiny antibodies naturally generated by llamas can be effective against COVID-19

As the fight against COVID-19 continues, scientists have turned to an unlikely source for a potentially effective treatment: tiny antibodies naturally generated by llamas.

10 Mar 2021

New compound can reduce overactivation without impairing the body's immunity response

When the body detects a pathogen, such as bacteria or viruses, it mounts an immune system response to fight this invader. In some people, the immune system overreacts, resulting in an overactive immune response that causes the body to injure itself, which may prove fatal in some cases.

10 Mar 2021

New SARS-CoV-2 vaccine candidate produces strong immune response, prevents SARS-CoV-2 infection

A new SARS-CoV-2 vaccine candidate, developed by giving a key protein's gene a ride into the body while encased in a measles vaccine, has been shown to produce a strong immune response and prevent SARS-CoV-2 infection and lung disease in multiple animal studies.

10 Mar 2021

Study examines m6A regulators and m6A-related genes through integrated bioinformatic analysis

Announcing a new article publication for BIO Integration journal. In this article the authors Jingdun Xie, Zhenhua Qi, Xiaolin Luo, Fang Yan, Wei Xing, Weian Zeng, Dongtai Chen and Qiang Li; from Sun Yat-sen University, Guangzhou, Guangdong, China discuss integration analysis of m6A regulators and m6A-related genes in hepatocellular carcinoma (HCC).

10 Mar 2021

Researchers discover new COVID-19 variants in three South African provinces

Variants of the coronavirus are appearing in different parts of the world, many of them spreading with alarming speed.

10 Mar 2021

Research demonstrates multivalent nanobodies overcome SARS-CoV-2 variant mutations

In a recent bioRxiv* preprint paper, researchers isolated anti-RBD nanobodies from llamas and “nanomice” (they engineered to produce VHHs cloned from alpacas, dromedaries and camels).

10 Mar 2021

Researchers develop AI-based tissue-section analysis system to diagnose breast cancer

Researchers at Charité - Universitätsmedizin Berlin and TU Berlin as well as the University of Oslo have developed a new tissue-section analysis system for diagnosing breast cancer based on artificial intelligence (AI).

10 Mar 2021

PRRT technology may offer new treatment approaches for neuroendocrine tumors

Neuroendocrine tumors are cancers that begin in specialized cells called neuroendocrine cells. These cells have traits similar to those of nerve cells and hormone-producing cells.

9 Mar 2021

New tumor-penetrating therapy may improve outcomes in patients with pancreatic cancer

Every 12 minutes, someone in the United States dies of pancreatic cancer, which is often diagnosed late, spreads rapidly and has a five-year survival rate at approximately 10 percent.

9 Mar 2021

SARS-CoV-2 variants rapidly arise in non-human hosts, potential risk for human reinfection

The study, published on the preprint server bioRxiv*, highlights the need to study viral evolution and pathogenesis in human and animal hosts. This could help prevent future outbreaks that may mimic the magnitude of the current COVID-19 pandemic.

9 Mar 2021

Scientists study seven human coronavirus envelope proteins using topology prediction and molecular modeling

A new study by researchers at the University of the Western Cape aimed to determine why some coronaviruses are more virulent than others. The team speculates that the increased flexibility of the PDZ-binding motif (PBM) of SARS-CoV, MERS-CoV, and SARS22 CoV-2 to be more flexible than the PBM of hCoVs 229E, NL63, OC43, and HKU1.

9 Mar 2021

First complete atlas of how mutations affect the formation of amyloid plaques in Alzheimer’s disease

A study published in the journal eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer's disease.

9 Mar 2021

Vaccine mRNA not found in breast milk after COVID mRNA vaccination

A study conducted by researchers in the United States has found no evidence to suggest that the messenger RNA (mRNA) present in the Pfizer-BioNTech and Moderna vaccines that protect against coronavirus disease 2019 (COVID-19) can be transferred to human breast milk.

9 Mar 2021

Phase 2 clinical trial is now open at Columbia to test gene therapy for dry macular degeneration

A phase 2 clinical trial is underway at Columbia University and NewYork-Presbyterian to test an investigational gene therapy for dry age-related macular degeneration, a progressive, chronic eye disease with no cure and a leading cause of blindness in the United States.

9 Mar 2021

Somatic gene mutations in brain cells could contribute to schizophrenia pathology

Schizophrenia is a neurodevelopmental disorder that disrupts brain activity producing hallucinations, delusions, and other cognitive disturbances. Researchers have long searched for genetic influences in the disease, but genetic mutations have been identified in only a small fraction--fewer than a quarter--of sequenced patients.

9 Mar 2021

Study describes the infection of human cells by intestinal pathogen during spaceflight

Astronauts face many challenges to their health, due to the exceptional conditions of spaceflight. Among these are a variety of infectious microbes that can attack their suppressed immune systems.

9 Mar 2021

Protein C News and Research

Researchers characterize antibody responses to COVID-19 mRNA-based vaccine

Researchers study prevalence of SARS-CoV-2 UK variant at University of Texas

Single mRNA vaccine dose may be enough for those previously exposed to SARS-CoV-2

Neutralizing antibodies may be evolving to keep up with SARS-CoV-2 mutations

Tiny antibodies naturally generated by llamas can be effective against COVID-19

New compound can reduce overactivation without impairing the body's immunity response

New SARS-CoV-2 vaccine candidate produces strong immune response, prevents SARS-CoV-2 infection

Study examines m6A regulators and m6A-related genes through integrated bioinformatic analysis

Researchers discover new COVID-19 variants in three South African provinces

Research demonstrates multivalent nanobodies overcome SARS-CoV-2 variant mutations

Researchers develop AI-based tissue-section analysis system to diagnose breast cancer

PRRT technology may offer new treatment approaches for neuroendocrine tumors

New tumor-penetrating therapy may improve outcomes in patients with pancreatic cancer

SARS-CoV-2 variants rapidly arise in non-human hosts, potential risk for human reinfection

Scientists study seven human coronavirus envelope proteins using topology prediction and molecular modeling

First complete atlas of how mutations affect the formation of amyloid plaques in Alzheimer’s disease

Vaccine mRNA not found in breast milk after COVID mRNA vaccination

Phase 2 clinical trial is now open at Columbia to test gene therapy for dry macular degeneration

Somatic gene mutations in brain cells could contribute to schizophrenia pathology

Study describes the infection of human cells by intestinal pathogen during spaceflight

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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