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Gold-containing drug auranofin kills 95% of SARS-CoV-2 virus in 48 hours in lab conditions

A drug called auranofin, approved for the treatment of rheumatoid arthritis, effectively inhibits severe acute respiratory syndrome coronavirus (SARS-CoV-2) in laboratory conditions, as described in a new study by Georgia State University researchers.

16 Apr 2020

New antiviral drug reduces transmission of influenza, study shows

The antiviral drug, baloxavir (tradename Xofluza), is the first treatment for influenza with a new mode of "action" to be licensed in nearly 20 years.

16 Apr 2020

Scripps Research establishes collaborative global effort to rapidly find drugs against COVID-19

With the COVID-19 pandemic continuing to spread across the globe, Scripps Research has quickly established an international network of collaborating scientific laboratories to leverage ReFRAME, the world's leading drug repurposing collection, to find antiviral compounds against the novel coronavirus.

16 Apr 2020

Super-resolution microscopy offers insight into the synapses

When people think of glutamate, the first thing they remember is the flavor enhancer that is often used in Asian cuisine.

16 Apr 2020

KHN’s ‘What the Health?’: How will we reopen the economy?

President Donald Trump wants to reopen the country soon. But public health experts from across the ideological spectrum insist that won't be safe until the country can dramatically ramp up testing and contact tracing stemming from those infected.

16 Apr 2020

With federal nod, consumers could lose the boost they get from drug ‘coupons’

Patients who get financial help from drug companies to cover their copayments for prescription drugs could owe a bigger chunk of their costs under a proposed federal rule.

16 Apr 2020

COPD lungs inundated by abnormal stem cells, research finds

Two internationally renowned stem cell experts have found an abundance of abnormal stem cells in the lungs of patients who suffer from Chronic Obstructive Pulmonary Disease, a leading cause of death worldwide.

16 Apr 2020

Remdesivir drug stops novel coronavirus from replicating

Scientists from the University of Alberta have published findings that the antiviral drug remdesivir prevents replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by inhibiting RNA replication. The study, published in April 2020 in the Journal of Biological Chemistry, follows on the heels of earlier reports from the same lab in February, showing the drug's effectiveness against the related Middle East Respiratory Syndrome (MERS) virus.

15 Apr 2020

Alzheimer's patients may need modified dosing regimens for selected drugs

Patients with Alzheimer's disease are often prescribed drugs for other conditions -- including diabetes or high blood pressure -- at the same doses as those without dementia.

15 Apr 2020

Bacterial metabolism of bile acids boosts generation of immune cells, study shows

A Ludwig Cancer Research study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells--immune cells that suppress autoimmune reactions and inflammation.

15 Apr 2020

Research Suggests Widespread Opioid Overprescribing has Lead to Opioid Epidemic

Research indicates that widespread opioid overprescribing contributed to the opioid epidemic.

15 Apr 2020

China with the world: COVID-19 experts dialogues - the 4th talk transcript

Q (Prof. Singer): What do you think about the comorbidities and the age of the patients in the treatment of COVID-19? Is the mortality higher in elderly patients as it is reported from recent papers?

From Mindray 15 Apr 2020

Study shows possible way to effectively deliver RNA drugs to tumors

In recent years, RNA molecules, with the ability to affect or turn off pathogenic genes, have become promising drug candidates in several areas.

15 Apr 2020

Autism in males may result from problems in brain-based immune cells

Many cases of autism spectrum disorders may result from problems in immune cells that normally work to trim back unneeded brain connections in early life, suggests a new study led by scientists at Scripps Research.

15 Apr 2020

Tarantula venom could be used as a potent pain reliever

Pain relief has come a long way, with many medicines developed to ease pain and promote comfort. Previous research has shown that venom can be a potent pain reliever. Snake venom has been widely studied as a potential source of pain relievers, especially for chronic and debilitating pain. Now, a team of scientists has found that spider venom, particularly from Tarantulas, could be used as a potent pain reliever for various conditions.

14 Apr 2020

The race is on for a coronavirus vaccine, 70 candidates, 3 at human trial stage

Amid the coronavirus disease (COVID-19) global pandemic that is infecting millions of people across the globe, hope sparks as the World Health Organization (WHO) reports that seventy vaccination trials for the novel coronavirus are underway, with three already at the human trial stage.

14 Apr 2020