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Single molecule FRET techniques combined with wavelet transforms give new view of AMPA receptor

A digital signal processing technique long used by statisticians to analyze data is helping Houston scientists understand the roots of memory and learning, Alzheimer's and Parkinson's diseases and stroke.

8 Feb 2011

Ansaris receives milestone payment for identification of kinase-related compound for cancer, autoimmune diseases

Ansaris announced today that it has received a milestone payment for the successful identification of a kinase-related compound under its drug discovery collaboration with Ono Pharmaceutical Co., Ltd. Ono will initiate the preclinical study of the identified compound. This collaboration between Ansaris and Ono was established to focus on the discovery of kinase-related compounds for the treatment of cancer, inflammatory and autoimmune diseases.

8 Feb 2011

Elan 2010 total revenue increases 5% to $1,169.7 million

Elan Corporation, plc today reported its fourth quarter and full-year 2010 financial results and provided financial guidance for 2011.

8 Feb 2011

Almac opens analytical facility at new 240,000 sq. ft. North American Headquarters

Almac's new 240,000 sq. ft. North American Headquarters, built on 40 acres in Souderton, PA, north of Philadelphia is part of the Almac Group's integrated services solutions strategy. The new facility delivers full-service, integrated clinical packaging, drug supply management and technology solutions to pharmaceutical and biotech clients.

8 Feb 2011

TREK1 activity offers a key target for fluoxetine and other antidepressant drugs

Using a unique and relatively simple cell-based fluorescent assay they developed, scientists with the U.S. Department of Energy's Lawrence Berkeley National Laboratory and the University of California, Berkeley have identified a means by which fluoxetine, the active ingredient in Prozac, suppresses the activity of the TREK1 potassium channel.

8 Feb 2011

Transition reports second quarter 2011 net income of $24.28M vs. $6.05M net loss for second quarter 2010

Transition Therapeutics Inc., a product-focused biopharmaceutical company developing therapeutics for disease indications with large markets, today announced its financial results for the quarter ended December 31, 2010.

8 Feb 2011

Researchers develop new method for drug discovery using math to combat HIV, other diseases

Using mathematical concepts, Princeton researchers have developed a method of discovering new drugs for a range of diseases by calculating which physical properties of biological molecules may predict their effectiveness as medicines.

8 Feb 2011

Munich research team provides promising alternative to DNA-based procedures

Defects in the genome are the cause of many diseases. Gene therapy - direct replacement of mutant genes by intact DNA copies - offers a means of correcting such defects. Now a research team based at the Medical Center of the University of Munich, and led by Privatdozent Dr. Carsten Rudolph, has taken a new approach that avoids DNA delivery.

8 Feb 2011

Two new sources of soybean may replace fish meal in weanling pig diets

Two new sources of soybean meal are capturing attention throughout the country. University of Illinois research indicates that fermented soybean meal and enzyme-treated soybean meal may replace fish meal in weanling pig diets.

7 Feb 2011

Researchers identify CHK1 protein may serve as treatment target for neuroblastoma

After analyzing hundreds of proteins produced by the DNA of tumor cells, researchers have identified one protein that may be central to a new treatment for the often-fatal childhood cancer neuroblastoma. Oncologists hope to translate the finding into pediatric clinical trials of a drug that blocks the protein's activity.

7 Feb 2011

Scientists develop low cost, nanometer-sized drug to treat chronic wounds

A low cost, nanometer-sized drug to treat chronic wounds, such as diabetic foot ulcers or burns, has been developed by a group of scientists from the Hebrew University of Jerusalem, Harvard Medical School and others in the U.S. and Japan.

7 Feb 2011

Human Vaccines journal publishes paper on Inovio's new DNA vaccine delivery technology

Inovio Pharmaceuticals, Inc., a leader in the development of therapeutic and preventive vaccines against cancers and infectious diseases, announced today that its new generation DNA vaccine delivery technology, which provides the powerful enabling capabilities of electroporation without contacting the skin, is highlighted in a paper published in the scientific journal Human Vaccines.

7 Feb 2011

Study: Fluorescent probe may serve as useful tool in future surgeries to repair injured nerves

Accidental damage to thin or buried nerves during surgery can have severe consequences, from chronic pain to permanent paralysis. Scientists at the University of California, San Diego School of Medicine may have found a remedy: injectable fluorescent peptides that cause hard-to-see peripheral nerves to glow, alerting surgeons to their location even before the nerves are encountered.

6 Feb 2011

Maxygen distributes Codexis's shares to its stockholders for U.S. Federal income tax purposes

Maxygen, Inc., a biotechnology company focused on the development of improved protein drugs, today announced that its distributions of Codexis, Inc. common stock and cash in December 2010 will be classified as a return of capital to its stockholders for U.S. Federal income tax purposes.

5 Feb 2011

New understanding of how host and foreign structures are distinguished by front-line defence mechanism

This week, the highly-respected US Academy of Sciences journal (PNAS) published an article describing how the first line of defence of the human immune system distinguishes between microbes and the body's own structures.

5 Feb 2011

Dermatologist's tips to reverse damage and maintain healthy, lustrous hair

While the latest hairstyles and hair colors may look great, dermatologists warn that many women are subjecting their hair to harsh chemicals and heated styling devices that, in turn, can damage the hair. Over time, lustrous hair can look lackluster, become brittle and require a complete hair care overhaul to improve hair health and appearance.

5 Feb 2011

Novel study finds unexpected link between reproductive proteins in humans, invertebrates

A novel study in the scientific journal Molecular Biology and Evolution draws a completely unexpected link between reproductive proteins in humans and proteins involved in fertilization in invertebrates, as well as mating between haploid cells in yeast. Because human and yeast are separated by 1 billion years of evolution, these findings may have important implications for our understanding of the molecular mechanisms underlying sex, and how they originated.

5 Feb 2011

Research provides new clues to understand link between deficits of AGPO-3, depression

The link between deficits of omega-3 poly-unsaturated fatty acids and the onset of depressive disorders is not new in the medical field. However, what has not been known until now is the brain mechanism by which diet can condition mental health to a certain extent.

5 Feb 2011

Lack of DOT1L enzyme could lead to some types of heart disease: Study

Everyone knows chocolate is critical to a happy Valentine's Day. Now scientists are one step closer to knowing what makes a heart happy the rest of the year.

5 Feb 2011

Scientists discover how stressed cells boost thrombin production

In our not-so-distant evolutionary past, stress often meant imminent danger, and the risk of blood loss, so part of our body's stress response is to stock-pile blood-clotting factors. Scientists in the Molecular Medicine Partnership Unit, a collaboration between the European Molecular Biology Laboratory in Heidelberg, Germany, and the University of Heidelberg Medical Centre, have discovered how stressed cells boost the production of the key blood-clotting factor, thrombin.

4 Feb 2011

G Protein News and Research

Single molecule FRET techniques combined with wavelet transforms give new view of AMPA receptor

Ansaris receives milestone payment for identification of kinase-related compound for cancer, autoimmune diseases

Elan 2010 total revenue increases 5% to $1,169.7 million

Almac opens analytical facility at new 240,000 sq. ft. North American Headquarters

TREK1 activity offers a key target for fluoxetine and other antidepressant drugs

Transition reports second quarter 2011 net income of $24.28M vs. $6.05M net loss for second quarter 2010

Researchers develop new method for drug discovery using math to combat HIV, other diseases

Munich research team provides promising alternative to DNA-based procedures

Two new sources of soybean may replace fish meal in weanling pig diets

Researchers identify CHK1 protein may serve as treatment target for neuroblastoma

Scientists develop low cost, nanometer-sized drug to treat chronic wounds

Human Vaccines journal publishes paper on Inovio's new DNA vaccine delivery technology

Study: Fluorescent probe may serve as useful tool in future surgeries to repair injured nerves

Maxygen distributes Codexis's shares to its stockholders for U.S. Federal income tax purposes

New understanding of how host and foreign structures are distinguished by front-line defence mechanism

Dermatologist's tips to reverse damage and maintain healthy, lustrous hair

Novel study finds unexpected link between reproductive proteins in humans, invertebrates

Research provides new clues to understand link between deficits of AGPO-3, depression

Lack of DOT1L enzyme could lead to some types of heart disease: Study

Scientists discover how stressed cells boost thrombin production

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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