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Therapies which boost the clearance of faulty proteins in cells may slow down ageing

Scientists say as people age, their cells become less efficient at getting rid of damaged protein and the result is a buildup of toxic material; this is particularly apparent in Alzheimer's, Parkinson's disease and other neurodegenerative disorders associated with ageing.

11 Aug 2008

Gab2 signalling protein switches off breast cancer and leukaemia

Australian scientists have identified a way to 'switch off' a molecule, a key player in the molecular processes that trigger breast cancer and certain forms of leukaemia.

10 Aug 2008

Researchers find a cancer-inhibiting cyanobacteria that grows on coral reefs

University of Florida College of Pharmacy researchers have discovered a marine compound off the coast of Key Largo that inhibits cancer cell growth in laboratory tests, a finding they hope will fuel the development of new drugs to better battle the disease.

10 Aug 2008

Scientists stop age-related decline in an entire organ

As people age, their cells become less efficient at getting rid of damaged protein - resulting in a buildup of toxic material that is especially pronounced in Alzheimer's, Parkinson's disease, and other neurodegenerative disorders.

10 Aug 2008

Nanowires from DNA

For millions of years nature has been optimizing DNA - in all living creatures this biomolecule is responsible for storing genetic information.

10 Aug 2008

BioNanomatrix awarded NIH grant for nanoscale platform for single-molecule DNA mapping

BioNanomatrix, Inc. has announced receipt of a grant from the National Human Genome Research Institute of the U.S. National Institutes of Health (NIH). Under the direction of BioNanomatrix principal investigator Dr. Ming Xiao, the two-year $399,020 project will develop a nanoscale platform for single-molecule haplotyping imaging and analysis of long strands of DNA at ultra-high resolution in a massively parallel format.

6 Aug 2008

Step forward in search for solution to Staphylococcus aureus infection

Scientists at the University of York have helped to reveal more about the way bacteria can attach to human tissues.

6 Aug 2008

Recipe for cell reprogramming adds protein

A drug-like molecule called Wnt can be substituted for the cancer gene c-Myc, one of four genes added to adult cells to reprogram them to an embryonic-stem-cell-like state, according to Whitehead researchers.

6 Aug 2008

How short RNAs influence many proteins

During the last decade, microRNAs have emerged somewhat surprisingly as key players in the way genes are regulated. These short snippets of RNA do their work by interacting with messenger RNAs, which act as blueprints for protein creation.

6 Aug 2008

A new target for malaria drugs

The malaria parasite has waged a successful guerrilla war against the human immune system for eons, but a study in this week's Journal of Biological Chemistry has exposed one of the tricks malaria uses to hide from the immune proteins, which may aid in future drug development.

4 Aug 2008

Cannabinoid cell surface receptor plays a tumor-suppressing role in human colorectal cancer

CB1 is well-established for relieving pain and nausea, elevating mood and stimulating appetite by serving as a docking station for the cannabinoid group of signaling molecules. It now may serve as a new path for cancer prevention or treatment.

3 Aug 2008

Scientists develop ultra-sensitive optical protein sensor, a first for a salivary diagnostic test

For people who dislike needles, medical tests that require a drop of saliva instead of a vial of blood will one day make a trip to a doctor or dentist much easier. But as scientists now construct the first of these saliva tests for early signs of cancer and other diseases, they continue to push the technological envelope in interesting ways.

3 Aug 2008

Newly identified risk factor for cardiovascular disease may lead to new treatments

Low levels of naturally occurring antibodies may represent an increased risk of developing cardiovascular disease, particularly stroke in men. This discovery, published in the academic journal Atherosclerosis, has now led to attempts to develop an immunization against cardiovascular disease.

31 Jul 2008

microRNA may influence development of alcohol tolerance

In recent years, a class of small molecules known as microRNAs have been found to play an important role in regulating gene products in most animal and plant species.

30 Jul 2008

ISU researchers find possible alternative adjuvant for alum to boost the effectiveness of vaccines

On the rocky road of cancer research, Indiana State University scientists have made important discoveries.

29 Jul 2008

Laboratory and mouse studies show targeted drug blocks the growth of breast cancer cells that spread to the brain

Using laboratory and mouse models of human breast cancer, researchers have found that a small molecule capable of targeting specific proteins on the surface of breast cancer cells can inhibit the growth of breast cancer cells that migrate to the brain.

29 Jul 2008

How anti-depressants and cocaine interact with brain

In a first, scientists from Weill Cornell Medical College and Columbia University Medical Center have described the specifics of how brain cells process antidepressant drugs, cocaine and amphetamines. These novel findings could prove useful in the development of more targeted medication therapies for a host of psychiatric diseases, most notably in the area of addiction.

28 Jul 2008

Lung inflammation from influenza and other infections could be turned off following new discovery

A new discovery could lead to treatments which turn off the inflammation in the lungs caused by influenza and other infections, according to a study published in the journal Nature Immunology.

27 Jul 2008

Researchers find key mechanism of cell damage in aging and disease

Researchers have taken a first snapshot of how a class of highly reactive molecules inflicts cellular damage as part of aging, heart disease, stroke, cancer, diabetes, kidney disease and Alzheimer's disease to name a few. According to a study published today in the journal Cell, researchers have discovered a tool that can monitor related damage and determine the degree to which antioxidant drugs effectively combat disease.

24 Jul 2008

New technique measures formation of clumps of proteins in protein-based pharmaceuticals

Scientists at the National Institute of Standards and Technology (NIST) have developed a technique to measure the formation of clumps of proteins in protein-based pharmaceuticals.

23 Jul 2008

Molecule News and Research

Therapies which boost the clearance of faulty proteins in cells may slow down ageing

Gab2 signalling protein switches off breast cancer and leukaemia

Researchers find a cancer-inhibiting cyanobacteria that grows on coral reefs

Scientists stop age-related decline in an entire organ

Nanowires from DNA

BioNanomatrix awarded NIH grant for nanoscale platform for single-molecule DNA mapping

Step forward in search for solution to Staphylococcus aureus infection

Recipe for cell reprogramming adds protein

How short RNAs influence many proteins

A new target for malaria drugs

Cannabinoid cell surface receptor plays a tumor-suppressing role in human colorectal cancer

Scientists develop ultra-sensitive optical protein sensor, a first for a salivary diagnostic test

Newly identified risk factor for cardiovascular disease may lead to new treatments

microRNA may influence development of alcohol tolerance

ISU researchers find possible alternative adjuvant for alum to boost the effectiveness of vaccines

Laboratory and mouse studies show targeted drug blocks the growth of breast cancer cells that spread to the brain

How anti-depressants and cocaine interact with brain

Lung inflammation from influenza and other infections could be turned off following new discovery

Researchers find key mechanism of cell damage in aging and disease

New technique measures formation of clumps of proteins in protein-based pharmaceuticals

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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