Blood Clot News and Research

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A Blood Clot is a mass of blood that forms when blood platelets, proteins, and cells stick together. When a blood clot is attached to the wall of a blood vessel, it is called a thrombus. When it moves through the bloodstream and blocks the flow of blood in another part of the body, it is called an embolus.

Study: Simultaneous knee replacement linked with higher risk of adverse cardiovascular outcomes within 30 days

Replacing both knees in one surgery, or simultaneous total knee replacement was associated with significantly fewer prosthetic joint infections as well as other revision knee operations within one year after surgery, compared with total knee replacements performed in two separate procedures.

17 Feb 2011

BCVI offers multidisciplinary approach to treat patients with atrial fibrillation

More than 2.6 million Americans suffer from atrial fibrillation —an erratic heartbeat. If left untreated, the condition can lead to stroke or heart failure. For three decades, 58 year old David Ryan was one of the millions of Americans suffering from the disease.

16 Feb 2011

Dabigatran drug helps prevent blood clots in patients with atrial fibrillation

The newly approved drug dabigatran is an alternative to warfarin to help prevent dangerous blood clots in patients with atrial fibrillation, according to updated guidelines from the American College of Cardiology, American Heart Association and the Heart Rhythm Society.

15 Feb 2011

Story of the heart: Literally as well as metaphorically

Stephen Amidon, a novelist and co-author of The Sublime Engine: A Biography of the Human Heart, writes about the story of the human heart through the world of science, history, culture and our bodies with his brother Thomas who is a practicing cardiologist in Montana and a former medical director of The Hope Heart Institute. Thomas said, “Ironically, I did an angiogram on a patient last week who had very calcified and hardened arteries that were almost precisely in the shape of the Valentine heart… But I don't think the early depicters of that heart shape had access to the same view of the heart that I have.”

14 Feb 2011

UH Case Stroke and Cerebrovascular Center increases tPA use for ischemic stroke by 13.5 times

University Hospitals Stroke and Cerebrovascular Center recently reported that it has increased the use of tPA or "clot busting therapy" for ischemic stroke by 13.5 times throughout UH system hospitals since implementing the System Stroke Program. Launched in 2008, SSP sought to increase access to the lifesaving treatment for acute ischemic stroke patients in the 15 counties surrounding Cleveland.

14 Feb 2011

JTH publishes positive TB-402 Phase II trial results for VTE treatment after orthopaedic surgery

ThromboGenics NV and co-development partner BioInvent International announce today that the positive TB-402 Phase II trial results, evaluating the product's efficacy and safety for the prevention of venous thromboembolism afterorthopaedic surgery, have been published in the Journal of Thrombosis and Haemostasis.

14 Feb 2011

Neurologic and neurosurgical patients do not receive therapy to prevent VTE: Study

Patients with strokes, brain tumors and spinal cord injuries are at high risk for life-threatening blood clots, but many do not receive preventive therapy, Loyola University Health System researchers report.

14 Feb 2011

Burden of stroke over next 40 years to skyrocket: Studies

Findings presented at the American Stroke Association’s International Stroke Conference in Los Angeles revealed that strokes are expected to rise by 350% over the next four decades.

13 Feb 2011

Daily diet soda raises stroke risk by 61%: Study

A new study suggests that regular intake of diet soda may be boosting the risk of stroke. Stroke is the third leading killer following heart disease and cancer, in the United States. More than 137,000 people a year die from stroke, according to the American Stroke Association.

13 Feb 2011

Athersys' MultiStem cell therapy provides multiple benefits in preclinical models of ischemic stroke

Medical researchers from The University of Texas Health Science Center at Houston (UTHealth) presented new research results at the American Heart Association International Stroke Conference that demonstrated how MultiStem-, a novel stem cell therapy being developed by Athersys, Inc. provided multiple benefits when administered in preclinical models of ischemic stroke.

11 Feb 2011

Alexion fourth quarter net product sales of Soliris increases to $156.0 million

Alexion Pharmaceuticals, Inc. today announced financial results for the quarter and year ended December 31, 2010. For the three months ended December 31, 2010, Alexion Pharmaceuticals, Inc. reported net product sales of Soliris® (eculizumab) of $156.0 million, reflecting strong additions of new patients, compared to $110.6 million for the same period in 2009.

10 Feb 2011

Luciferase enzyme offers promise for improved monitoring of heparin therapy: New study

The enzyme that makes fireflies glow is lighting up the scientific path toward a long-sought new medical imaging agent to better monitor treatment with heparin, the blood thinner that millions of people take to prevent or treat blood clots, scientists are reporting. Their study appears in the ACS' monthly journal Bioconjugate Chemistry.

10 Feb 2011

PolyMedix commences PMX-60056 Phase 2 clinical trial in patients undergoing PCI

PolyMedix, Inc., an emerging biotechnology company focused on developing new therapeutic drugs to treat infectious diseases and acute cardiovascular disorders, has initiated a Phase 2 clinical trial, following conclusion of a review by the United States Food and Drug Administration (FDA) of a protocol submitted by PolyMedix, to assess the safety and efficacy of its heptagonist, PMX-60056, in reversing heparin in patients undergoing Percutaneous Coronary Intervention (PCI) procedures.

9 Feb 2011

Pharmacist-directed anticoagulation service improves quality of care for HIT patients

A Henry Ford Hospital study has found that a pharmacist-directed anticoagulation service improves the way medication is managed for patients with heparin-induced thrombocytopenia, a common but life-threatening thromboembolic disorder.

9 Feb 2011

FDA approves Makena injection to reduce risk of preterm delivery

The U.S. Food and Drug Administration today approved Makena (hydroxyprogesterone caproate) injection to reduce the risk of preterm delivery before 37 weeks of pregnancy, in pregnant women with a history of at least one spontaneous preterm birth.

5 Feb 2011

Scientists discover how stressed cells boost thrombin production

In our not-so-distant evolutionary past, stress often meant imminent danger, and the risk of blood loss, so part of our body's stress response is to stock-pile blood-clotting factors. Scientists in the Molecular Medicine Partnership Unit, a collaboration between the European Molecular Biology Laboratory in Heidelberg, Germany, and the University of Heidelberg Medical Centre, have discovered how stressed cells boost the production of the key blood-clotting factor, thrombin.

4 Feb 2011

Scientists discover how stressed cells boost production of key blood-clotting factor, thrombin

Scientists in a collaboration between EMBL Heidelberg and the University of Heidelberg Medical Centre have discovered how stressed cells boost the production of the key blood-clotting factor, thrombin. Their work, published today in Molecular Cell, shows how cancer cells may be taking advantage of this process, and opens new possibilities for fighting back against cancer and septicaemia.

4 Feb 2011

CVT more common than previously thought, disproportionally affects pregnant women

A rare and often underreported form of stroke that involves veins instead of arteries is more common than previously thought, according to the American Heart Association's first scientific statement on diagnosing and managing cerebral venous thrombosis (CVT).

4 Feb 2011

Scientia Advisors: Unmet need for new medical technologies to treat CVI and blood clots

In light of an aging population and increasing chronic vascular disease, there is a tremendous unmet need for new medical technologies to treat potentially dangerous chronic venous insufficiency (CVI) and blood clots, according to a Scientia Advisors review of the vascular device market released today. Both the CVI and the thrombosis segments present significant opportunities for medical device innovators.

3 Feb 2011

Researchers design nanoparticles that make blood clots visible to CT scanner

For almost two decades, cardiologists have searched for ways to see dangerous blood clots before they cause heart attacks. Now, researchers at Washington University School of Medicine in St. Louis report that they have designed nanoparticles that find clots and make them visible to a new kind of X-ray technology.

3 Feb 2011

Blood Clot News and Research

Further Reading

Study: Simultaneous knee replacement linked with higher risk of adverse cardiovascular outcomes within 30 days

BCVI offers multidisciplinary approach to treat patients with atrial fibrillation

Dabigatran drug helps prevent blood clots in patients with atrial fibrillation

Story of the heart: Literally as well as metaphorically

UH Case Stroke and Cerebrovascular Center increases tPA use for ischemic stroke by 13.5 times

JTH publishes positive TB-402 Phase II trial results for VTE treatment after orthopaedic surgery

Neurologic and neurosurgical patients do not receive therapy to prevent VTE: Study

Burden of stroke over next 40 years to skyrocket: Studies

Daily diet soda raises stroke risk by 61%: Study

Athersys' MultiStem cell therapy provides multiple benefits in preclinical models of ischemic stroke

Alexion fourth quarter net product sales of Soliris increases to $156.0 million

Luciferase enzyme offers promise for improved monitoring of heparin therapy: New study

PolyMedix commences PMX-60056 Phase 2 clinical trial in patients undergoing PCI

Pharmacist-directed anticoagulation service improves quality of care for HIT patients

FDA approves Makena injection to reduce risk of preterm delivery

Scientists discover how stressed cells boost thrombin production

Scientists discover how stressed cells boost production of key blood-clotting factor, thrombin

CVT more common than previously thought, disproportionally affects pregnant women

Scientia Advisors: Unmet need for new medical technologies to treat CVI and blood clots

Researchers design nanoparticles that make blood clots visible to CT scanner

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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